10 Best Weed Vine Killer of 2025

Tested and Reviewed: Top 10 Weed Vine Killer deals with expert ratings from 8.1 to a perfect 10

May 2025 Edition

Editor's Choice

9.7

Bonide

Bonide 2746 Stump & Vine Killer Concentrate, 8 oz Stumps and Vines Without harming Turf. Contains Brush Easy Application. Kills Oak, Poison Ivy and More, 1

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Editor's bottom line:

“This weed vine killer is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

CONTROL WOODY PLANTS & VINES-Stop undesirable listed woody vines, plants and broadleaf weeds.
ALSO USED AS STUMP KILLER-Use undiluted to kill stumps and prevent sprouting.
USE AS FOLIAR SPRAY-Can be applied using a hose-end or tank sprayer.
FOR OUTDOOR USE-Around homes, cabins, fences & walkways.
WORKS QUICKLY-Eliminates weeds within 1-6 weeks.

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Picked by 317 people today

9.5

Save 16%

BioAdvanced

BioAdvanced Brush Killer Plus, Ready-to-Use, 1 Gal – Kills Tough Brush Roots & All, Kills Poison Ivy

16% Off

Main Highlights

POISON IVY KILLER: Plus it kills Kudzu, Poison Oak, Blackberry and 75+ types of listed weeds and brush
KILLS DOWN TO THE ROOT: Kills listed weeds above and the root below
RESULTS: Start seeing visual results in 1- 6 weeks
RAINPROOF PROTECTION: Rainproof in 4 hours

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9.5

Save 29%

Southern Ag

Southern AG 01113 Brush Weed Killer, 1 Quart (32 oz)

29% OffFree Shipping

Main Highlights

This brush control herbicide is easy to use
Kills vines and many hard to control plants
Prevents sprouting on clean-cut stumps
Use on non-crop areas like road sides, rangeland, pastures and fences

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9.2

Pulverize

Pulverize Weed Brush and Vine Killer, Fast Acting, Non-Staining, Safe for People and Pets, All Year Round, Herbicide for Poison Ivy, Vines, and Weeds, Concentrate - 32 oz.

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Main Highlights

FAST-ACTING formula that targets weeds, brush and vine all year round with results within 20 minutes
ACTIVE INGREDIENTS: Includes active ingredients Ammoniated Soap of Fatty Acids and Maleic Hydrazide that eliminates poison ivy, poison oak, and other unwanted garden pests
NON-STAINING formula - making it safe to spray on your concrete, pavement, and other outdoor surfaces with no fear of residue
SAFE TO USE around kids, pets, and vegetable gardens, Pulverize is strong enough to handle deep-rooted weeds without harming soil
EASY TO USE simply mix concentrate and apply to pulverize unwanted weeds, brush, and vines

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9.0

Pulverize

Pulverize Weed, Brush & Vine Killer Ready to Use

Free Shipping

Main Highlights

Kills the toughtest weeds
Roots and all!
Non staining
works quickly / Kills the roots!
use anytime of the year

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8.8

Save 14%

Roundup

Roundup Weed & Grass Killer₄ with Pump 'N Go 2 Sprayer, Use In and Around Flower Beds, Trees & More, 1.33 gal.

14% OffFree Shipping

Main Highlights

Roundup Weed & Grass Killer kills tough weeds and grasses to the root, including dandelion, crabgrass, poison ivy, clover (red & white), spotted spurge, and other broadleaf weeds
It is rainproof in as fast as 30 minutes and produces visible results in hours
Allows for planting 1 to 30 days after application (see booklet for details)
Use in or around flower beds and perennial landscape plants, around trees and shrubs, on patios, walkways, and driveways, gravel, or mulch beds, along fences and foundations, and edging around foundations and retaining walls
The Pump N Go 2 Sprayer with an extendable wand provides up to 10 minutes of continuous spray and provides greater accuracy without bending over

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Best Value

8.6

Save 31%

Pulverize

Pulverize PWBV-B-128-S, Brush & Vine Ready to Use Weed Killer, Clear

31% OffFree Shipping

Main Highlights

Kills the toughtest weeds
Roots and all!
Non staining
works quickly / Kills the roots!
use anytime of the year

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8.3

Bonide

Bonide Vine & Stump Killer With Applicator Concentrate 8 Oz, 2 Pack

Free Shipping

Main Highlights

KILLS TOUGH BRUSH: Kills Stumps, Brush, Suckers & More!
EASY TO USE: Trim your tree or shrub & simply paint on!
VALUE 2 PACK: 2 PACK VALUE

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8.1

Save 25%

Roundup

Roundup Poison Ivy Plus Tough Brush Killer₂ Concentrate, Visible Results in Hours, 32 fl. oz.

25% OffFree Shipping

Main Highlights

Roundup Poison Ivy Plus Tough Brush Killer Concentrate is an exclusive formula that kills poison ivy, poison oak, poison sumac, wild blackberry, kudzu, and all types of tough weeds
Rainproof in as fast as 30 minutes and produces visible results in hours
Allows for planting 1 to 30 days after application (see booklet for details)
Use this weed control in residential fields and trails, around trees or shrubs, around homes, buildings, cabins, lodges, and camp sites, along fences and foundations, on vines growing up poles or mature trees, freshly cut woody stumps, and other areas where tough weed are invading your yard
Mix Roundup Poison Ivy Plus Tough Brush Killer Concentrate according to label directions and spot treat or spray evenly each gallon of spray solution over 300 sq. ft. with a tank or hose-end sprayer

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8.1

Save 11%

Ortho

Ortho GroundClear Poison Ivy and Tough Brush Killer3 with Comfort Wand, Ready-To-Use Weed Killer with Results in 1 Hour, 1 gal.

11% OffFree Shipping

Main Highlights

Ortho GroundClear Poison Ivy & Tough Brush Killer3 controls over 60 types of listed tough weeds and brush, including poison ivy, poison oak, kudzu and wild blackberry
This weed killer gets to work immediately to produce visible results in just 1 hour, and is rainproof in 2 hours
Use this poison ivy killer around homes, cabins, buildings, fences and trails; not recommended for use in lawns or gardens with desirable plants
Apply this brush killer to weed and brush foliage, stems and trunks when weeds are actively growing and leafed out
This 1 gal. container of Ortho GroundClear Poison Ivy & Tough Brush Killer3 comes with the battery-powered Comfort Wand applicator to accurately target weeds and brush

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Our Best Overall Choice

Best Choice

9.7

Bonide

Bonide 2746 Stump & Vine Killer Concentrate, 8 oz Stumps and Vines Without harming Turf. Contains Brush Easy Application. Kills Oak, Poison Ivy and More, 1

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

CONTROL WOODY PLANTS & VINES-Stop undesirable listed woody vines, plants and broadleaf weeds.
ALSO USED AS STUMP KILLER-Use undiluted to kill stumps and prevent sprouting.
USE AS FOLIAR SPRAY-Can be applied using a hose-end or tank sprayer.
FOR OUTDOOR USE-Around homes, cabins, fences & walkways.
WORKS QUICKLY-Eliminates weeds within 1-6 weeks.

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Roundup Poison Ivy Plus Tough Brush Killer₂ Concentrate, Visible Results in Hours, 32 fl. oz.

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Spruce Weed Killer Spray - Snap & Spray Weed & Grass Killer₂ Powered Starter Kit - Reusable Sprayer with Wand for Spot-Treating Driveways, Gardens & More - Results in 1 Hour (64 Oz Bottle)

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