10 Best Vitamins Methylated of 2025

Tested and Reviewed: Top 10 Vitamins Methylated deals with expert ratings from 8.1 to a perfect 10

July 2025 Edition

Editor's Choice

9.7

Save 5%

Igennus Healthcare Nutrition

Igennus Super B-Complex Methylated B Vitamins, Sustained Release, Clean Label, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets

5% OffFree Shipping

Editor's bottom line:

“This vitamins methylated is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

METHYLATED B VITAMINS AND FOLATE that the body utilises immediately: bioavailable folate as methylfolate & methylcobalamin (Vit B12) - no poorly absorbed cyanocobalamin*
HIGH STRENGTH, SUPER ABSORBABLE B complex vitamins including thiamine (B1), Riboflavin-5-phosphate (B2), Nicotinamide (flush free Niacin - B3), Calcium D-pantothenate (B5) & D-Biotin (B7)*
SUSTAINED RELEASE technology gradually releases vitamins (important for optimising B12 levels), whilst twice daily dosing provides all-day nutrient coverage*
INTENSIVE HEALTH SUPPORT for energy metabolism, the immune and hormonal systems, homocysteine regulation, nutrient metabolism, heart function and psychological function*
PURE & CLEAN: vegan, non-GMO, hypoallergenic ingredients, no unpleasant fillers (silicon dioxide, magnesium stearate or titanium dioxide). Lab verified, USA & UK GMP manufactured. Small 9mm tablets

Show Price

Picked by 180 people today

Best Value

9.5

Save 15%

Igennus Healthcare Nutrition

Igennus Methylated Men's Multivitamin, MTHFR Supplement with Active B-Vitamins, 21 Highly Bioavailable Nutrients, Multivitamin for Sustained Release, Clean Label, Non-GMO & Halal 60 Tablets

15% OffFree Shipping

Main Highlights

METHYLATED & ACTIVE FORMS - each nutrient form has been carefully selected to optimize the journey from supplement to cell. Includes methylated B-vitamins, chelated minerals and gentle zinc (new label, same advanced formula, you may receive either label)*
SLOW-RELEASE FORMULA: blood nutrient levels are optimized with bioactive vitamin forms & slow-release formula. Take 1 tablet twice per day as a split dose
MULTIVITAMIN FOR MEN: 22 high-potency nutrients including bioactive B-complex, chelated minerals and antioxidant complex enhanced with lycopene; iron-free
MORE OF WHAT YOU NEED, LESS OF WHAT YOU DON'T - our nutritionists have formulated a comprehensive multivitamin for men, topping up nutrients often lacking in everyday diets, without unnecessary extras*
PURE & CLEAN: lab-verified ingredients; UK GMP manufactured; vegan; no silicon dioxide or magnesium stearate; fully recyclable packaging; easy-to-swallow oval tablets

Show Price

9.5

NUTRAHARMONY

Methylated Multivitamin - B-Complex with Methylfolate & B12 - for Men & Women - 9-in-1 MTHFR Supplement with TMG - for Energy, Brain & Mood - Vegan, Lab Tested - Made in USA - 120 Capsules, One/Day

Free Shipping

Main Highlights

9-in-1 Methylated Multivitamin power through your day with 9 essential methylation support vitamins B2, B6, B9, B12, C, D3, E, K2 & Trimethylglycine packed into a single, easy-to-take capsule. Methylated B Complex designed to deliver your daily nutritional needs, this formula features activated, bioavailable vitamin forms that fuel your wellness journey helping you thrive with just one capsule a day.
Active & Bioavailable Vitamins supercharge your body with L-Methylfolate the most bioavailable form of Folate to maintain optimal levels and enhance critical methylation processes. Feel the boost of potent Vitamin B12 Methylcobalamin for all-day energy, paired with activated Vitamins B2 and B6 to power your metabolism, support radiant skin, and strengthen your nervous system.
Methylation, Brain & Energy Support supports natural energy & vitality, helps reduce the feeling of fatigue with essential Methylated B Complex that aid healthy folate levels, balanced homocysteine, and the methylation process. Includes key vitamins to support cognitive function, sharpness, and a balanced mood for a calm, focused lifestyle.
Made in USA With Globally Sourced Ingredients our methylated multivitamin supplement is proudly manufactured in the USA under strict quality control standards. Non-GMO, DYE-free, No Gluten & Soy-Free, and GMP-certified, methylated multivitamin for men & women are produced with the most potent ingredients for maximum efficacy & purity in every batch.
Trustworthy Service at NUTRAHARMONY, we are committed to providing only premium-quality supplements, including our carefully crafted Methylated B Complex vitamins. Our exceptional customer service ensures that your satisfaction is our top priority, making your wellness journey as seamless and trustworthy as possible.

Show Price

9.2

Double Wood Supplements

Methylated Multivitamin (Methylated and Activated Vitamins Only - B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood

Free Shipping

Main Highlights

METHYLATED FORMS OF VITAMINS: Double Wood's Methylated Multivitamin contains only methylated / activated forms of vitamins that are already usable by the body and do not need to be further converted in order to be bioavailable
METHYLATED B COMPLEX: Contains the Methylated / Activated Coenzyme form of Vitamin B2 (R-5-P), Vitamin B6 (P-5P) and Vitamin B12 (Methylcobalamin and Dibencozide)(Methyl B12)
SIX TOTAL METHYLATED VITAMINS: Contains trimethylglycine and calcium L-5-methyltetrahydrofolate (MTHFR multivitamin) to help support healthy folic acid levels and control homocysteine levels in the body. It is important to use methylated folic acid since standard folic acid is inert in the body and cannot be processed further by many people
CAN COMBINE WITH A NORMAL MULTIVITAMIN: Double Wood's Methylated Multivitamin can be combined with a regular multivitamin for those looking to also supplement with inactive vitamins or vitamins such as Magnesium and Vitamin D
WE BOTTLE WELLNESS: At Double Wood we provide pure, potent supplements that deliver exceptional value, all backed by careful sourcing and rigorous third-party testing

Show Price

9.0

Triquetra Health

L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioactive Forms of Vitamin B9 & B12 (60 Capsules – 60 Servings)

Free Shipping

Main Highlights

HIGH-POTENCY: Provides a high-potency serving of 15mg L-Methylfolate in the 5-MTHF calcium salt form. This bioactive form of folate is readily utilized by the body.
VITAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships that work together in the body's methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is vital for those with methylation issues that cannot properly process folic acid.
SUPPORTS BRAIN, MOOD & ENERGY HEALTH: Important for healthy neurotransmitter function linked to focus, energy, and a balanced mood.
SUPPORTS CARDIOVASCULAR, NITRIC OXIDE & NERVE HEALTH: Helps maintain healthy homocysteine levels, promotes normal heart function, and supports nitric oxide production for overall circulatory and nerve well-being.

Show Price

8.8

Micro Ingredients

Pure Methylated Multivitamin for Men & Women | 240 Capsules with Vitamins C, D, B12, Thiamin, Folate + Magnesium, Zinc, & More | High Absorption | Bioactive Vitamin & Mineral Complex | Filler Free

Free Shipping

Main Highlights

Micro Ingredients offers a Pure Methylated Multivitamin Complex. 19-in-1 support with high absorption bioactive forms. 240 capsules that feature raw, active ingredients with no fillers.
Each serving provides active methylated vitamins like fat-soluble vitamin C (ascorbyl palmitate), A (retinyl palmitate), D3 (cholecalciferol), E (d- alpha tocopherol), thiamin HCl, riboflavin (R5P), niacin (niacinamide), B6 (P5P), folate, B12 (methylcobalamin), biotin, and pantothenic acid.
An advanced multivitamin combined with key minerals for promoting various health benefits that include energy, cellular, heart, immune, and brain support for men and women.
Enjoy only active ingredients that use high bioavailable methylated vitamins and minerals for efficiently refilling key nutritional gaps over time.
Premium non-GMO multivitamins supplement. Made without fillers, soy, dairy, wheat, gluten, fish, shellfish, peanuts, and tree nuts. Ingredients must pass our 3rd party lab tests to ensure a product that is safe, pure, and potent.

Show Price

8.6

Livingood Daily

Livingood Daily Methylated Multivitamin for Women & Men, Multi Vitamin - Mineral Supplement Capsules with Iron, B Complex, Selenium, & Zinc - Non-GMO, Gluten-Free, Vegetarian Multi Vitamins for Adults

Free Shipping

Main Highlights

Complete Nourishment: Livingood Daily Multivitamin is a 25-in-1 formula that packs all your essential vitamins and minerals into one supplement you can take daily to promote energy levels, metabolism, brain health and more! 60 vegetarian capsules.
All of Your Essentials: Livingood Daily Multivitamin is loaded with optimal levels of necessities like B Vitamins and Zinc, critical for brain and immune health, Iron and Iodine, critical for supporting energy levels and metabolism, and Selenium, a powerful antioxidant
Easy to Take: If swallowing full capsules is difficult, Multivitamin can be opened, and the contents inside can be put into any food or beverage of choice.
Works With Any Lifestyle: Our supplements are perfect for vegetarian diets and are free from allergens, GMOs and gluten.
Experience Real Health: Founded by best-selling author Dr. Blake Livingood, Livingood Daily is dedicated to helping you take back your health with thoughtful and unique product combinations, so you can get more out of each dose and live good!

Show Price

8.3

Inessa

Inessa Methylated Multivitamin for Men and Women - Advanced Natural Daily Mens Multivitamins with CoQ10 100mg, Vitamins D3, K2, A, B Complex Vitamins, Folic Acid & Zinc - 60 Vegan Tablets

Free Shipping

Main Highlights

[Feel Like You, But Better] You want to thrive, not just survive. You want best, not just better, health. So meet the cutting-edge multivitamin supplement designed with your optimal wellness in mind. This magical multivitamin with K2 and vitamin D3 is productivity powerhouse that keeps you feeling fresh and focused, all-day-long.
[Daily Wellness, Simplified] - Why take multiple supplements to get everything you need? This one-a-day wonder has 25 ingredients in highly bioavailable doses crammed into every dose. Its one of the only multivitamins that works like an antioxidant complex, B-complex, CoQ10, vitamin D3 and vitamin K2 supplement in one.
[Vegan Society Approved] Eating clean? We hear you. This women's and mens vegan multivitamin is also allergen, gluten and dairy free. But dont just take our word for it. We batch test our multivitamin supplement for purity and it contains no unnecessary additives, chemicals, flavorings or color.
[Fights Fatigue] Micronutrient deficiencies can impact your vitality, and even healthy diets may not give you everything you need for boundless energy. But with relevant doses of CoQ10, B-complex vitamins, D3, iodine and more, this women's and mens multivitamin will put the natural spring back into your step.
[Nature's Nourishment] - Embrace a natural approach to wellness with our gluten-free, vegan multivitamin. Crafted for modern men like you, it champions your dietary choices while enriching your health journey. Make every day a step toward a healthier, happier you!

Show Price

8.1

Pure Therapro Rx

Methyl Multi Without Iron Methylated Multivitamin for Men & Women, 120-Day Supply | Methyl B12 & Methylfolate (5-MTHF) for MTHFR Support | Pharma Grade Multivitamin & Multimineral For Health, 240 Caps

Free Shipping

Main Highlights

: Discussed on The Joe Rogan Experience with Gary Brecka, our Methyl Multi without Iron is a vegan-friendly, hypoallergenic, and meticulously-researched multivitamin and multimineral supplement made from high-quality ingredients with zero fillers. Our comprehensive formulation promotes healthy cognitive function and supports antioxidant protection and detoxication. Methyl Multi is the ultimate multivitamin to support total-body wellness and optimum vitality.
: When supplementing, absorption is key! Methyl Multi without Iron is formulated with Quatrefolic Folate (5-MTHF), Albion TRAACS mineral chelates, and other micronutrients in their pre-methylated and coenzyme forms for optimal absorption and bioavailability, all together in patented EMBOCAPS AP60 acid resistant vegetable capsules designed for a guaranteed 60 minutes of acid-protection.
: Millions of Americans have MTHFR and/or COMT mutations, making it difficult for their bodies to process key vitamins like B12 and Folate. Methyl Multi without Iron contains pre-methylated forms of B12 and Folate for increased bioavailability, which can help to support healthy metabolism, energy release from food, detoxification, and nervous system function.
? For those extremely sensitive or new to methylated vitamins, we recommend gradually increasing the amount you are taking so your body can adapt. A small percentage of customers can experience a temporary detoxification / Herxheimer response. Symptoms may include: headache, lethargy, skin rash / hives, respiratory symptoms (cough, sore throat). These are temporary and a sign that the supplement is working. However if your body detoxes too quickly at one time it can overload your detox pathways! Its imperative to lower the amount you are taking for a few days and work your way up slowly to the full dose LOW & SLOW
: Pure TheraPro Rx Methyl Multi without Iron contain no fillers such as rice flour, cornstarch, or wood pulp fibers. Our manufacturing facility adheres to strict NSF/cGMP guidelines. Consumer safety and satisfaction are our highest priority, which is why our products undergo rigorous third-party testing and screening to ensure product purity and potency.
: Pure TheraPro Rx was founded in Denver Colorado to formulate and manufacture the highest quality supplements available on the market today. Purity is our priority, which is why we insist on using patented, clinically studied ingredients, and never utilizing fillers, flow agents, excipients, or ingredients sourced from China. We also never use dairy, gluten, corn, soy, or other common allergens in any of our class-leading, practitioner-recommended formulas.

Show Price

8.1

10X Health System

10X Health Optimize Methylated Multivitamin for Men & Women - 34 in 1 Formula with 800 mcg of Vitamin B12, Vitamin E, 5-MTHF, B Complex, NAC, Magnesium & Zinc Multivitamins - 90 Capsules

Free Shipping

Main Highlights

Targeted Nutritional Support: 10x Optimize methylated multivitamins offer the ultimate multivitamin and mineral formula to address genetic deficits in your methylation pathway. This impacts your overall wellness and supports optimal health.
Essential Methylated Nutrients: This includes crucial methylated vitamins like 5-MTHF (methylated folic acid), methylated B12, riboflavin (B2), and pyridoxine (B6). This multivitamin-methylated formula supports your body's natural methylation processes.
Vital Minerals for Balance: Formulated with optimized minerals such as magnesium and zinc, 10X Optimize multivitamins for women and men help to maintain essential mineral balance and support the immune system, energy production, and cognitive function.
Additional Methylation Support: Contains NAC (N-acetyl L-cysteine), a powerful amino acid known for its excellent support of the methylation pathway. NAC helps boost your body's ability to boost antioxidant levels and promote cellular health.
Quality and Safety Focused: The 10X Optimize methylated multivitamin from 10X Health System is proudly made in the USA using premium, carefully sourced ingredients. Each batch undergoes rigorous quality and purity testing, ensuring your wellness.

Show Price

Our Best Overall Choice

Best Choice

9.7

Igennus Healthcare Nutrition

Igennus Super B-Complex Methylated B Vitamins, Sustained Release, Clean Label, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets

5% OffFree Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

METHYLATED B VITAMINS AND FOLATE that the body utilises immediately: bioavailable folate as methylfolate & methylcobalamin (Vit B12) - no poorly absorbed cyanocobalamin*
HIGH STRENGTH, SUPER ABSORBABLE B complex vitamins including thiamine (B1), Riboflavin-5-phosphate (B2), Nicotinamide (flush free Niacin - B3), Calcium D-pantothenate (B5) & D-Biotin (B7)*
SUSTAINED RELEASE technology gradually releases vitamins (important for optimising B12 levels), whilst twice daily dosing provides all-day nutrient coverage*
INTENSIVE HEALTH SUPPORT for energy metabolism, the immune and hormonal systems, homocysteine regulation, nutrient metabolism, heart function and psychological function*
PURE & CLEAN: vegan, non-GMO, hypoallergenic ingredients, no unpleasant fillers (silicon dioxide, magnesium stearate or titanium dioxide). Lab verified, USA & UK GMP manufactured. Small 9mm tablets

Show Price

Related Deals You Might Like for Vitamins Methylated

Methylated Multivitamin Women Men, Vitamin D3 K2 5000IU / 10,000IU, B12 5000 mcg 2500mcg, K2 (MK-7) 240mcg- ADK+Methyl Vitamin B12, Vegan D3,Vitamin A,C,Zinc Eye,Bone,Energy,Immune, Sugar-Free Gummies

Show PriceView

Igennus Methylated Kids Multivitamin Gummy, MTHFR Supplement with B-Vitamins & Vitamin D, No Artificial Sweeteners or Flavors, Sugar Free, Age 4+, 90 Berry Gummies, Non-GMO, Halal, Clean Label

16% Off

Show PriceView

envitamin Methylated Multivitamin Multimineral Complex L Methylfolate

Show PriceView

Eliixr Methylated Multivitamin Supplement for Men and Women with Active Methyl B12 and 5-MTHF Methylfolate 60 Vegetable Capsules Iron Free Made in The USA

Show PriceView

Sugar-Free Methylated Multivitamin for Women Gummies w/Algae Calcium, Vitamin A, C, D3, E, K, B12, Iron, Folate, Biotin, Inositol - Multi Vitamins & Minerals for Skin, Hair, Energy, Immune, Bone Vegan

Show PriceView

Power By Naturals Methyl Multi One - Iron-Free Methylated Multivitamin with Quatrefolic 5-MTHF, Active B12, P5P, CoQ10 & Zinc for MTHFR Support - Energy & Focus Formula - 60 Capsules (2-Month Supply)

15% Off

Show PriceView

NatureGenX Just One Daily Methylated Multivitamin - 60 Caps Pure Methyl B12, Methylfolate MTHFR Support Supplement Iron Free Methylated Vitamins for Men & Women 2 Months Supply Gluten Free

15% Off

Show PriceView

Pure Encapsulations O.N.E. Multivitamin - Once Daily Multivitamin with Antioxidant Complex Metafolin, CoQ10, and Lutein to Support Vision, Cognitive Function, and Cellular Health* - 60 Capsules

Show PriceView

Pure TheraPro Rx Methylated B Complex Vitamins Made in USA, 4 Month Supply | Methyl B Complete Quatrefolic 5-MTHF Folate, B12 Methylcobalamin, TMG Trimethylglycine, Methylfolate | Pharm Grade

Show PriceView

THORNE Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12-180 Capsules

Show PriceView

Deals are Live

Special Amazon deal ends in: