10 Best Slow Release Melatonin of 2025

Tested and Reviewed: Top 10 Slow Release Melatonin deals with expert ratings from 8.1 to a perfect 10

September 2025 Edition

Editor's Choice

9.7

Pure Encapsulations

Pure Encapsulations Melatonin-SR - Extended Release Melatonin - Supports Restful Sleep* - Sleep Supplement - Gluten Free & Vegan - 60 Capsules

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Editor's bottom line:

“This slow release melatonin is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Sleep Support: Our Pure Encapsulations Melatonin-SR ensures prolonged absorption for a 6-hour sleep supplement support*
Restful Sleep Support: Melatonin SR aids relaxation and sleep patterns to support a peaceful nights sleep*
Pure Ingredients for Natural Support: Supports the body's circadian rhythm and endocrine secretions for high-quality gluten-free sleep supplementation*
Suggested Use: As a dietary supplement, take 1 sleep supplement capsule 30-60 minutes before bedtime
Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs

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Picked by 267 people today

9.5

Save 16%

Nature Made

Nature Made Wellblends Sleep Longer, Melatonin 10mg, L theanine 100 mg, and GABA 100mg, Sleep Supplement, 35 Tri-Layer Tablets

16% Off

Main Highlights

SLEEP BLEND WITH RESULTS YOU CAN FEEL(3): Nature Made Wellblends Sleep Longer Tablets provide 3 benefits in 1 blend with ingredients to improve your sleep quality (1)
POWERED BY SCIENCE(1): Maximum Strength Melatonin 10mg (2), L theanine 100 mg and GABA 100 mg for restful sleep support
BLEND OF L THEANINE AND GABA: Unwind by relaxing your mind with L-theanine and help support a calm and relaxed mental state with GABA
TIME RELEASE TECHNOLOGY: Immediate-release Melatonin helps you fall asleep faster and extended-release Melatonin supports a restful nights sleep
SCIENCE-BACKED SOLUTIONS YOU CAN TRUST: Blended by Nature Made, powered by science(1)
HIGH QUALITY INGREDIENTS: This gluten-free occasional use sleep aid is 100% drug free and non-habit forming; Adults, take 1 tablet one hour before bedtime with water
#1 PHARMACIST RECOMMENDED VITAMIN & SUPPLEMENT BRAND: Based on a survey of pharmacists who recommend branded vitamins and supplements
These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease

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9.5

Save 16%

Natrol

Natrol 10 mg Melatonin Gummies, Time Release Sleep Gummies for Adults, Minimize Wake Ups, Strawberry-Flavored, 55 Count, 55 Day Supply

16% OffFree Shipping

Main Highlights

SLEEP SUPPORT THROUGH THE NIGHT: Experience better sleep with melatonin 10mg gummies for adults, formulated as a time release melatonin supplement to help minimize wake-ups and promote restful sleep (1)
TIME RELEASE MELATONIN: These melatonin gummies 10mg are formulated with quick release melatonin combined with melatonin extended release for continuous sleep support (1)
ANTIOXIDANT DEFENSE: Natrol melatonin 10mg gummies offers antioxidant properties to combat free radicals while supporting adult melatonin needs (1)
100% DRUG-FREE AND NON-HABIT FORMING: Adult melatonin gummies are 100% drug-free, non habit-forming, vegetarian and gelatin-free, made without synthetic dyes or artificial flavors
DELICIOUS STRAWBERRY FLAVOR: These Melatonin 10 mg feature a delicious strawberry flavor and are a pectin-based melatonin gummy, providing an easy addition to your nightly sleep support routine
#1 DRUG FREE SLEEP AID BRAND IN AMERICA(2): As the #1 drug free sleep aid brand, we not only have formulas to help you fall asleep faster, we also offer fast-acting and effective formulas that can help calm your mind and body and maintain good health

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9.2

Save 39%

Natrol

Natrol Melatonin 10mg Tablets, Advanced Sleep Dietary Supplement for Restful Sleep, 100 Melatonin Time Release Tablets, 100 Servings

39% OffFree Shipping

Main Highlights

PROMOTES BETTER SLEEP: Natrol Melatonin 10mg Time Release offers a nighttime sleep aid supplement that releases Melatonin quickly to help you fall asleep faster, and a release of melatonin extended release to support sleep through the night (1)
TIME RELEASE FORMULA: The dual-layer tablet in Natrol 10mg Melatonin provides quick dissolving outer layer to help you fall asleep faster and a controlled release inner layer of melatonin extended release to help you stay asleep through the night (1)
100-DAY SUPPLY: Each bottle of Natrol 10 mg Melatonin has 100 non-habit forming time release tablets, giving you up to a 100 night supply
100% DRUG-FREE: This adult melatonin sleep aid supplement are 100% drug-free and non-habit forming
SUPPORTS SLEEP CYCLES: Melatonin 10 mg supports sleep cycles disrupted by stress with elements like Vitamin B6, making it a great choice for sleeping aids for adults

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9.0

Save 39%

NOW Foods

NOW Foods Supplements, Melatonin 5 mg, Sustained Release, Formulated for a 4-Hour Release Period, 120 Tablets

39% OffFree Shipping

Main Highlights

HEALTHY SLEEP CYCLE*: Melatonin is a potent free radical scavenger naturally produced in the pineal gland and present in high amounts in the gastrointestinal tract*
GI SUPPORT*: It is involved in many of the body, brain and glandular biological functions including regulation of normal sleep/wake cycles, regulation of the immune system and maintenance of a healthy gastrointestinal lining*
VEGAN: This sustained release tablet is formulated to release over a 4-hour period
GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
Packaged in the USA by a family owned and operated company since 1968

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8.8

Life Extension

Life Extension Melatonin 6 Hour Timed Release, 300 mcg, Extended-Release Formula for Gentle Sleep Support, Healthy circadian Rhythms, Cellular Defense, Gluten-Free, Non-GMO, Vegetarian, 100 Tablets

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Main Highlights

Long lasting sleep support Melatonin is a hormone that your body releases, mostly at night, to help you sleep. It encourages falling asleep and staying asleep for a good nights rest.
Circadian rhythms Modern lifestyles, aging and other factors can disrupt our circadian clocks, which can affect our health. Melatonin helps restore optimal sleep-wake cycles.
Circadian rhythms Modern lifestyles, aging and other factors can disrupt our circadian clocks, which can affect our health. Melatonin helps restore optimal sleep-wake cycles.
Ingredients matter We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USAand a Certificate of Analysis is available for every one.
Live your healthiest life We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. Thats why so many of our formulas feature specific ingredients and amounts based on scientific studies.

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8.6

Save 15%

21st Century

21st Century Melatonin 10 Mg Prolonged Release, 120 Count

15% OffFree Shipping

Main Highlights

Dietary Supplement
Prolonged release
Sleep support

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8.3

Save 24%

Nature's Bounty

Nature's Bounty Melatonin 5mg Dual Spectrum, 100% Drug Free Sleep Supplement, Quick Release and Extended Release, Promotes Relaxation and Sleep Health, 60 Bi-Layer Tablets

24% OffFree Shipping

Main Highlights

A DRUG-FREE SLEEP AID (1): Melatonin is a hormone naturally found in the body, offering a 100% drug-free way to support relaxation and restful sleep (1)
BI-LAYER TECHNOLOGY: Natures Bounty Dual Spectrum Melatonin tablets include quick release and time release Melatonin layers, helping you fall asleep faster and stay asleep longer (1)
PROMOTES SOUND, CALM SLEEP (1): Melatonin nutritionally supports rest and relaxation to aid with occasional sleeplessness, so you can enjoy sound sleep and wake up feeling refreshed (1)
GLUTEN, DAIRY, AND WHEAT FREE: Natures Bounty Dual-Spectrum Melatonin tablets are gluten free, dairy free, wheat free, and contain no artificial flavors or sweeteners
UNSURPASSED QUALITY AND VALUE: Using the latest breakthroughs in nutritional science and the finest ingredients, Natures Bounty provides supplements of unsurpassed quality and value

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8.1

Save 26%

Natrol

Natrol Melatonin 3 mg Time Release, Dietary Supplement to Minimize Wake Ups, Nighttime Sleep Aid, 100 Tablets, Up to a 100 Day Supply

26% OffFree Shipping

Main Highlights

#1 DRUG FREE SLEEP AID BRAND IN AMERICA(2): As the #1 drug free sleep aid brand, we not only have formulas to help you fall asleep faster, we also offer fast-acting and effective formulas that can help calm your mind and body and maintain good health
SLEEP SUPPORT THROUGH THE NIGHT: Two-layer melatonin tablet is formulated with a quick dissolving outer layer to help you fall asleep fast and a controlled release inner layer to help you sleep through the night by minimizing wake-ups(1)
HELP WITH OCCASIONAL SLEEPLESSNESS: Natrol Melatonin supplements for occasional sleeplessness contain 3 mg of melatonin and 10 mg of Vitamin B6 to help you fall asleep faster, stay asleep longer, and wake up feeling refreshed(1)
FALL ASLEEP FASTER, STAY ASLEEP LONGER: Natrol time release melatonin for sleep support promotes sleep in as little as 15 minutes(1)
100% DRUG-FREE SLEEP AID SUPPLEMENT: These time release sleep aid melatonin dietary supplements are 100% drug-free, and non-habit forming

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Best Value

8.1

Save 43%

Nature's Bounty

Melatonin by Nature's Bounty, Sleep3 Maximum Strength 100% Drug Free Sleep Aid, Dietary Supplement, L-Theanine & Nighttime Herbal Blend Time Release Technology, 10mg, 30 Tri-Layered Tablets

43% OffFree Shipping

Main Highlights

100% DRUG-FREE SLEEP AID: Nature's Bounty Sleep3 is a maximum-strength, 100% drug-free sleep aid that uses Triple Action Time Release Technology with 10mg of Melatonin
L-THEANINE & NIGHTTIME HERBAL BLEND: Calming L-Theanine combined with a blend of nighttime herbs chamomile, lavender, lemon balm and valerian root extracts help you relax and unwind
MAXIMUM STRENGTH WITH 10 MG OF MELATONIN: Natures Bounty Sleep3 features 10 mg melatonin with triple action time release technology which works with your bodys natural sleep cycle to help you stay asleep longer (1)
SLEEP SUPPORT SUPPLEMENT (1): Natures Bounty Sleep3 is non-GMO and contains no artificial flavor or sweetener; no sugar; no milk; no lactose; no soy; no yeast; and no fish; is sodium free; gluten free; and suitable for vegetarians
TRUSTED QUALITY AND LABORATORY TESTED: For 50 years we have been making trusted productsbacked by science made with only the best ingredients and delivering unsurpassed quality and value

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Our Best Overall Choice

Best Choice

9.7

Pure Encapsulations

Pure Encapsulations Melatonin-SR - Extended Release Melatonin - Supports Restful Sleep* - Sleep Supplement - Gluten Free & Vegan - 60 Capsules

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Sleep Support: Our Pure Encapsulations Melatonin-SR ensures prolonged absorption for a 6-hour sleep supplement support*
Restful Sleep Support: Melatonin SR aids relaxation and sleep patterns to support a peaceful nights sleep*
Pure Ingredients for Natural Support: Supports the body's circadian rhythm and endocrine secretions for high-quality gluten-free sleep supplementation*
Suggested Use: As a dietary supplement, take 1 sleep supplement capsule 30-60 minutes before bedtime
Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs

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