10 Best Preservative Free Contact Lens Rewetting Drops of 2025

Tested and Reviewed: Top 10 Preservative Free Contact Lens Rewetting Drops deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Biotrue

Biotrue Hydration Boost for Contacts, Rehydrating Eye Drops for Dry Eyes, Preservative Free, Refreshes, Lubricates & Moisturizes Lenses, Rewetting Eye Drops, 0.33 FL Oz (Pack of 1)

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Editor's bottom line:

“This preservative free contact lens rewetting drops is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost for Contacts are enhanced with HA (Hyaluronan), Antioxidant (Protects HA from free radicals), and Electrolyte.
LASTING MOISTURE: For up to 8 hours of moisture (based on a laboratory study) and to help prevent deposit buildup.
REWETTING DROPS FOR CONTACT LENSES: Biotrue Hydration Boost for Contacts are the first preservative free multi-dose contact lens drops.
BIOTRUE CONTACT LENS DROPS: Not only are Biotrue Hydration Boost for Contacts free of preservatives but they are also pH balanced for comfort.
EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, & ointments to help your contacts and eyes feel moisturized and protected.

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Picked by 397 people today

9.5

Biotrue

Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 1)

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Main Highlights

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
Special preservative free, multi-dose bottle.
BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced for comfort.
EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.

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9.5

Opti-Free

Opti-Free Puremoist Rewetting Drops, 12-mL

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Main Highlights

Opti-Free Puremoist Rewetting Drops give you a refreshing burst of moisture for added comfort when wearing contact lenses
Removes particles that cause irritation
Helps prevent deposit build-up
For Use with all Silicone Hydrogel and other Soft Contact Lenses

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9.2

BLINK

Blink-N-Clean Contact Lens Drop, Rewetting Drops for Soft & RGP Contact Lenses, Instantly Moisturizes, Removes Lens Build-Up, Cleans Lenses and Hydrates Eyes During Wear, 0.5 Fl Oz

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Main Highlights

Relief with Every Blink: Over the course of the day, a film of protein and other material can build up on your contact lenses, irritating your eyes. Blink eye drops for contact lenses provide convenient and gentle in-eye contact lens cleaning
Clean & Moisturize: Blink sterile, preserved rewetting drops for contact lenses do more than just moisturize, they clean too. The dual cleansing formula gently removes build up and moisturizes your contact lenses while you wear them
On-the-Go Cleaning: Experience the convenience of in-eye cleaning. These contact lens eye drops gently remove particles and material that can cause irritation and discomfort, keeping your lenses feeling fresh and your vision clear
Works for All Lenses: Whether you wear soft or rigid gas permeable lenses, our contact rewetting drops instantly moisturize and gently cleanse your lenses. Enjoy the benefits of a moisturizing and cleansing solution that suits your contact lens type
Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated. Blink products provide comfort and hydration, to help your eyes and contacts feel moisturized

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9.0

Refresh

Refresh Relieva for Contacts Lubricant Eye Drops For Dry Eyes, 0.27 Fl Oz Sterile

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Main Highlights

ENHANCED FORMULA: Dry eye relief scientifically designed for contact lens wearers
FAST ACTING: Instantly lubricates and wets contact lenses to relieve dryness, burning, irritation, and discomfort in the eye
EASY TO USE: You may keep your contacts in during application
INNOVATIVE: The only artificial tears for contact lens wearers with carboxymethylcellulose (CMC), glycerin, hyaluronic acid (HA) (inactive ingredient), and HydroCell technology
SOOTHING: Safe to use as often as needed and as a contact lens rewetter
FEATURING PURITE: Preservative that eliminates bacteria, is gentle enough for use as needed, and breaks down into natural tear components when administered in the eye
FAVORED: The #1 selling brand in contact lens rewetters (Data on file, Abbvie, Inc. REF-132086)
TRUSTED: #1 doctor recommended artificial tears from the brand with over 35 years of experience (Data on file, AbbVie, Inc. REF-113774)
FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense, depending on your plan

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8.8

Refresh

Refresh Contacts, Eye Drops For Dry Eyes, Contact Lens Comfort, 0.4 Fl Oz Sterile

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Main Highlights

MOISTURE-RICH RELIEF: Soothes contact lens dryness
INNOVATIVE: Cushions lenses prior to application as it lubricates and rewets contacts
EASY TO USE: You may keep your contacts in during application
RELIABLE PROTECTION: Active ingredients provide lasting lubrication for dry eyes
ORIGINAL STRENGTH FORMULA: Lubricates and rewets soft and rigid gas permeable (RGP) lenses. Silicone acrylate and fluorosilicone acrylate rigid gas permeable lenses are recommended for use with REFRESH CONTACTS. Consult your eye care practitioner to identify the lens you wear. May also be used to lubricate and rewet soft contact lenses and to cushion lenses prior to application
FEATURING PURITE: Preservative that eliminates bacteria, is gentle enough for use as needed, and breaks down into natural tear components when administered in the eye
SOOTHING: Safe to use as often as needed and as a contact lens rewetter
TRUSTED: #1 doctor recommended for artificial tears from the brand with over 35 years of experience (Data on file, AbbVie, Inc. REF-113774)
FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense, depending on your plan

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8.6

Renu

Renu Lubricant Eye Drops, Rewetting Drops for Contact Lenses, Rehydrates Soft & Disposable Lenses, Soothes & Moisturizes Eyes for Comfort, 0.27 Fl Oz (Pack of 1)

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Main Highlights

Rewetting contact eye drops: Lubricates and rewets while you wear your contact lenses. Ideal for extended wear, frequent replacement, and disposable soft lenses. Helps keep eyes comfortable.
Comfort and moisture: Solution that soothes, and moisturizes, and refreshes lenses. Helps relieve dryness and irritation caused by contact lens wear.
Bausch + Lomb Eye Care: Trusted by eye care professionals since 1853, Bausch + Lomb offers a complete range of solutions including eye drops, supplements, lens care, and contact lens solution. Each product supports and maintains overall eye health.
Renu Value: Trusted by over millions households nationwide, Renu offers everyday value in contact lens solution and rewetting drops from the eye care experts at Bausch + Lomb.
Please review all label information upon delivery to ensure proper handling and use.

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8.3

BLINK

Blink Contacts Lubricating Eye Drops with Hyaluronate, Moisturizing & Soothing for Soft & RGP Contact Lenses, Refreshes Lenses, Hydrating & Comforting Daily Eye Care, 0.34 Fl Oz

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Main Highlights

Relief with Every Blink: Blink Contacts Lubricating Eye Drops moisturize dry contact lenses to provide long-lasting comfort. These drops work with the eye's natural tears to help keep your contact lenses feeling fresh and comfortable all day
Hydration Boost with Hyaluronate: Our moisturizing eye drops instantly moisturize dry lenses. Our unique hyaluronate formulate works as a hydration booster to help contacts stay refreshed and comfortable through end of day
Comfort till End of Day: Blink Contacts Lubricating Eye Drops are formulated with beneficial electrolytes similar to those found in natural tears. Enjoy the freedom to wear your soft or RGP lenses while experiencing long-lasting comfort
Moisturizes Dry Lenses: The Blink Contacts Lubricating Eye Drops rewet and moisturize lenses before insertion and during wear, moisturizing and refreshing lenses. They reduce the feeling of contact lens dryness to help maintain comfort to the end of the day and reduce discomfort that may lead to removing your lenses early
Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated. Blink products provide comfort and hydration, to help your eyes and contacts feel moisturized

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8.1

Refresh

Refresh Relieva PF Lubricant Eye Drops for Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count

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Main Highlights

Preservative free formula relieves discomfort due to dry, irritated eyes
Prevents further irritation
Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
Recommended for sensitive eyes
Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.

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8.1

Systane

Systane Contacts Soothing Drops-0.405 oz, 12mL

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Main Highlights

Moisturize and soothe dry eyes caused by wearing soft and RGP lenses.

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Our Best Overall Choice

Best Choice

9.7

Biotrue

Biotrue Hydration Boost for Contacts, Rehydrating Eye Drops for Dry Eyes, Preservative Free, Refreshes, Lubricates & Moisturizes Lenses, Rewetting Eye Drops, 0.33 FL Oz (Pack of 1)

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Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost for Contacts are enhanced with HA (Hyaluronan), Antioxidant (Protects HA from free radicals), and Electrolyte.
LASTING MOISTURE: For up to 8 hours of moisture (based on a laboratory study) and to help prevent deposit buildup.
REWETTING DROPS FOR CONTACT LENSES: Biotrue Hydration Boost for Contacts are the first preservative free multi-dose contact lens drops.
BIOTRUE CONTACT LENS DROPS: Not only are Biotrue Hydration Boost for Contacts free of preservatives but they are also pH balanced for comfort.
EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, & ointments to help your contacts and eyes feel moisturized and protected.

Show Price

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