10 Best Portable Medicine Small Refrigerator of 2025

Tested and Reviewed: Top 10 Portable Medicine Small Refrigerator deals with expert ratings from 8.1 to a perfect 10

May 2025 Edition

Editor's Choice

9.7

SECRETSBOX

SECRETSBOX Medication Cooler for Travel TSA Approved Medicine Cooler with 36-46℉ Digital Display Portable Mini Refrigerator for Medicine Diabetic Travel Case 1 Battery 20000mAh

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Editor's bottom line:

“This portable medicine small refrigerator is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Material: Aluminum+ ABS+Eco-friendly Plastic
Core Technology: AUTO Thermoregulation System + Precise Temperature Control+Anti-freeze
Product Infor9.4x5.7x3.7 inches (Lx Wx H) Weight: 4.3lb
Warrantees: Lifetime Maintenance+ 3 Monthes Free Change or Money Back
Newly Anti Freeze Technology Designed: This medication cooler equipped with the latest high-tech chip, has non stop cooling effect. Cooling fast when the box turn on, will automatically shut off when the temperature drops to 36/2 and will automatically turn on when the temperature reach to 46/8. This allows for better refrigeration, prevents overheat and freezing. It can put 4 normal insulin pens and more injections,or you can use it as a mini fridge
Long Time Endurance and Power Alarming: The new patented diabetic insulin cooler travel case box contains 1 original rechargeable battery, 1 battery can last 9-12 hours in summer. When the TSA approved insulin cooler machine is low on power, the cooler box will intermittently beep to remind you to charge or replace the battery. In addition, the battery also can be used as power bank to charge other electronic device
4 Power Modes Suit All Charging Occasion: The new design cooler machine can be powered by the equipped battery, 5V power bank, USB or plug. It allow you to take plane, train or bus with our medicine cooling box. Suitable for home, office,travel,trip, driving, camping and all other activity. Our diabetic supplies travel cooling case will secure your medication safety at any time
Portable Handbag and Multifunctional Digital Display : The new designed insulin cooing case equipped with digital display that shows the inner temperature in real time and remaining power, also allow you to set a alarming to remind you to eat half an hour later after insulin injection. Anti-loss card,you can put your information on it. Hand strap allow you to take it up and down. Portable bag can be carried on shoulder or back. Fashionable in appearance and useful for privacy protection
How to Use and After Sell Service: Press the switch key or plug in the power supply, let the cooling box work for a while, open the lid, put in insulin pens or other medicines that need to be refrigerated, and close the lid. We promise free change or money back if you are not satisfied with our product within 90 days. Please contact us first if you have any issues when using the insulin cooling case, We offer lifetime after sell service about tech issues

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Picked by 196 people today

9.5

CGOLDENWALL

CGOLDENWALL Portable Insulin Cooler Box for Max.12 Pens, 7.5 * 3 * 2.7inches Internal Capacity 32-64℉ Setting with 5V 13600MAH Battery Mini Medicine Refrigerator for Home &Outdoor Use

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Main Highlights

1.UPGRADED HUGE STORAGE SPACE: The internal space of the insulin cooler box (7.5*3*2.7inches) can accommodate approximately 12 insulin pens or 75 insulin cartridge replacements or 36 insulin vials. Even large growth hormone pens no longer pose a storage problem. (The external size: 9.3*7*4inches)
2. DUAL-LAYER DESIGN: Comes with a partition basket, the portable medicine refrigerator box has a slightly higher temperature in the upper layer than the bottom layer, suitable for storing different types of medicines and prevent freezing damage due to low temperature.
3. LONG STANDBY TIME: Equipped with one built-in batteries, the medicine refrigerator box with a capacity of 13600MAH, used alternately, can keep your medicines cool for a total of about 6 hours in an environment temperature of 95.
4. MULTIPLE POWER SUPPLY METHODS: Besides battery power, as long as the output current exceeds 3A, whether it's a USB socket in a hotel or airplane, or a car power supply, all can be used to supply power to the medicine refrigerator box.
5. LED BIG SCREEN DISPLAY: One-click setting of 46, with simple power-on and temperature adjustment buttons, making it easy for the elderly to operate. In case of any operational malfunctions, we will resolve them within 2 working days.
6. TEMPERATURE CONTROL BY CATEGORY: This insulin cooler box uses a brand-new powerful cooling chip, with the external power supply temperature control range of 32-64, and the lithium battery temperature control range of 39-64.
7. HANDLE DESIGN: The medicine refrigerator box is equipped with a side handle, ensuring portability while maintaining a large capacity. Perfect for outdoor workouts, business trips, or short travels.
8. FLIGHT APPROVAL: The CGOLDENWALL refrigerator box comes with a qualified battery flight certificate. If you need to travel by plane, please contact us for an electronic version of the certificate.

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9.5

HYUNLAI

HYUNLAI Insulin Cooler Case Portable Insulin Refrigerator with Temperature LED Display Screen Keeping Cooling 35℉ ~ 46 F, Insulin Fridge with Handle & Alarm USB Chargerable (White)

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Main Highlights

Insulin travel cooler makes it easy to operate and read. One-key setting to , you can reach the desired temperature without complicated settings for
The insulin refrigerator's precise storage at can satisfy most usage scenarios.
The medicine cooler is designed for travel and home. Insulin Refrigerator can be powered by USB cables, wall chargers, power banks,
This Insulin refrige could storage 4-5 insulin pens or 7 Insulin bottles or 15 insulin refills.
When the Insulin storage device is low on power, the cooler box will intermittently beep to remind you to charge or replace the battery.

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9.2

QIRDLP

QIRDLP （Upgraded version） Insulin Cooler Case portable Diabetic cooler Box Mini Drug Refrigerator Keeping Cooling 2-8℃ with handle, alarm & USB Chargerable（1 layer Celsius temperature

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Main Highlights

LED screen temperature touch control screen; Portable; 0~8° fast cooling;Easy using. Charge the battery fully for 7 hours can keep longer working time ! Insulin cooler travel case can put in 6-9 insulin pens, or 25 bottles,or 60 refills.
Multiple charging modes 110V-240V adapter,USB cable,portable batteries,/car/home/battery can be used,suitable for travel,home,commuting,business travel and office,etc.Suitable for various places such as travel, home, business, and office.
1 year warranty and TSA Approved. QIRDLP insulin cooler travel case is for diabetics.Thank you for choosing our products, we will serve you wholeheartedly.[ Don't forget to Close ] Avoid exposes medicines to extreme temperatures . Note: 1. Do not cover the ventilation slots. 2. Do not use in high temperature or immerse in water.Please contact us when any problem.

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9.0

Nother

Insulin Cooler Case USB Mini Medicine Refrigerator Portable Cooler Box, 13600mAh Battery & Bag, Constant Temperature Refrigerator

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Main Highlights

1.The high-definition LCD touch screen is simple and easy to understand,Power display and temperature display making it easier for the elderly to operate.The arc angle design of the inner tank prevents the drugs from bumping in the box during the journey. Sandblasting and anodizing process makes the refrigerating temperature lasting.
2.Cold storage temperature: 2-835.6-46.4, operating temperature below 2577If the room temperature over 25 the case can`t cooler below 8.
3.Insulin Notes:can put about 3 insulin pens or ,6 bottles or 20 refills; The cooler box can fast cooling in ten minutes,the portable battery standby time is more than 10 hours.
4.Power supply: USB cable,wall charger,power bank, car, home, storage battery can be used, suitable for travel, home, commuting, business trip and office.
5.Medicines need to be stored separately to avoid cross-infection, store separately for safe and healthyThank you for choosing our products, we will serve you wholeheartedly.[ Don't forget to Close ] Avoid exposes medicines to extreme temperatures .

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8.8

QIRDLP

Insulin Cooler Travel Box,Mini Drug Refrigerator Keeping Cooling 2-8℃ car Cooler Box, Portable Diabetic Box Cooler Box (Mini)

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Main Highlights

1. LED Intelligent Touch Screen --- The Medicine refrigerator has an LED intelligent touch screen temperature control screen, which can accurately display the temperature inside the box and adjust the temperature as needed anytime and anywhere. Very easy to operate and use, even for the elderly. Powered for use, no need any refrigerant or ice .
2. Fast Cooling in 15 mints --- The new upgraded medicine fridge can drop from room temperature to 2 ° C ~ 8 ° C in 15 minutes. Provide a constant temperature storage environment for insulin, eye drops, serum, and other items that require refrigeration.
3. Multiple Power supply --- QIRDLP insulin cooler for travel with: USB cable,wall charger,2 pcs rechargable battery easily used in car, home, hotel,suitable for travel, home, commuting, business trip and office.
4.Portable mini size ,easy going to everywhere you want. Can put 3 insulin pens.
5.Medicines need to be stored separately to avoid cross-infection, store separately for safe and health.Thank you for choosing our products, we will serve you wholeheartedly.[ Don't forget to Close ] Avoid exposes medicines to extreme temperatures . Note: 1. Do not cover the ventilation slots. 2. Do not use in high temperature or immerse in water.Please contact us when any problem.

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8.6

Save 5%

AstroAI

AstroAI Mini Fridge, 4 Liter/6 Can AC/DC Portable Thermoelectric Cooler Refrigerators for Skincare, Beverage, Food, Home, Office and Car, ETL Listed (Black)

5% OffFree Shipping

Main Highlights

Compact Mini Fridge: The AstroAI mini fridge is a small fridge built to store food, drinks, beer, snacks, breast milk, makeup, skincare products, and more. It is great for bedrooms, offices, dorms, travel, boating, camping, and beyond
4-Liter Capacity: This fridge easily stores 6 cans (12oz); its inner dimensions are 5.5 x 5.3 x 8.07. It also features a removable shelf that makes small items like drinks, beers, breast milk, skincare, cosmetics, or food easy to separate. Giving this mini fridge is an excellent way to express love to friends and family
AC/DC Adapters: You can connect the compact refrigerator to a 100-120V home power supply or a 12V car power supply. NOTE: Make sure to only run your cooler while your vehicles engine is on, running the fridge without the engine on risks draining your vehicles battery
Quiet & Safe: The fridges semiconductor refrigeration chip is freon-free. Noise-quieting technology keeps sound at a minimum (25dB), so you can rest easy- even with the fridge right next to you. Please note: 1. Users shouldnt frequently open the door and should promptly close the door after accessing their items. 2. It needs sufficient heat dissipation space; it should be placed in a location with at least 2 inches of clearance on all sides. 3. Dont directly put hot food inside of the fridge
Cooling: The lowest interior temperature of the fridge cannot be colder than 32°F (0). The cooling effect depends on the ambient temperature and cooling time. This fridge cools through the thermoelectric process (coolsup to 32-59°F), which has a different cooling effect from household fridges (freezes from -4-68°F). CE, FCC, ETL, RoHS certified

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8.3

Simple Deluxe

Simple Deluxe 4L/6 Can Mini, Portable Cooler & Warmer Freon-Free Small Refrigerator, Compact Fridge for Skincare, Beverage, Food, Cosmetics, Black

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Main Highlights

Compact and portable: 4-Liter capacity that can store up to six 12 oz cans. The interior size is 5.5*5.1*8.1 inches. Comes with a removable shelf and convenient carry handle, great for bedroom, offices, dorms, camping and more! Capacity: 4 liters
Multiple functions: Set the mini fridge to cool or warm just flip a switch! Cool up to 34°F (18-20°C below ambient temperature) and keep warm up to 131°F (55°C), great for the storage food, drinks, cosmetics and skincare. An ideal gift for women
Adapter: You can connect the fridge to a 100-120V home power supply, perfect for indoor and outdoor.
Eco-friendly and quiet operation: 100% Freon-Free. Use advanced semiconductors that are free of CFCs and refrigerants. And the chips are more powerful, long-lasting durability and energy efficient. With the ability to perform quietly (25 dB Sleep Mode)
Package include: 1*black mini refrigerator host, power cord, 1*internal partition storage room shelf, 1*storage box, 1*English manual

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8.1

VEVOR

VEVOR Mini Fridge, 4 Liter/6 Can Small Refrigerator for Beverage Skincare & Cosmetic, AC/DC Cooler & Warmer, Mute Portable Tiny Fridge for Bedroom Office Dorm Desk Car Travel, ETL Certified, Black

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Main Highlights

Cooling & Warming: Our mini fridge features both cooling and warming functions, allowing you to adjust the mode to your desired temperature. The cooling mode can reach below 64.4 ambient temperature, while the warming mode can go up to 122 ambient temperature. It only takes one hour to achieve the corresponding cooling effect.
User-friendly Design: No more worries about water leakage! We've upgraded our portable refrigerator with a water collection tank located at the bottom of the fridge to collect any condensed water inside the fridge. A towel is also included to wipe off any excess condensed water. Remember to drain the collected water regularly to keep your fridge clean and dry.
Quiet Operation: The considerate noise reduction technology ensures that the fridge operates at a noise level of less than 38bd, making it quieter and less disruptive to work and daily life. It won't disturb your rest and is perfect for any setting - be it your bedroom, office or nursery.
Compact but Spacious: Our mini-fridge features a small body, but it can hold up to six 330ml cans in its 4L capacity, weighing only 4.08lbs. Its soft PU handle makes it portable and easy to carry, ideal for storing food, drinks, breast milk, skincare products, medicine, and more.
Versatile and Convenient: The personal fridge comes with both a USB power cable and a household power adapter, making it suitable for self-driving and outdoor activities. Its sleek design and practical functions also make it a great gift for loved ones and friends who enjoy hiking, picnics, or camping trips.

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Best Value

8.1

Save 33%

Sweetcrispy

Sweetcrispy Mini Fridge, Portable Small Refrigerator 4L/6 Can Cooler & Warmer Compact Fridges for SkinCare, Food and Drinks, Bedroom, Dorm, Car, Office, White

33% OffFree Shipping

Main Highlights

MULTIFUNCTION SMALL FRIDGE: This mini refrigerator is ideal for storing lunch, drinks, breast milk, cosmetics, and skincare products. It's versatile and practical, making it a must-have for any home, office, dormitory, or on-the-go travel situation.
COMPACT AND PORTABLE MINI FRIDGE: With a 4-liter capacity that can hold up to 6 cans of 12-ounce soda, this compact fridge is everything you need for convenient storage. Its interior dimensions are 5.3x6x8 inches and it features a removable shelf and handy carry handle for added convenience.
ADJUSTABLE THERMOSTAT CONTROL: This mini fridge offers precise temperature control. Simply flip a switch to make the fridge either cool or warm. It can cool down to 32°F (0°C) and maintain warmth up to 131°F (55°C), it works both in summer and winter.
ECO-FRIENDLY & QUIET: Benefiting from an advanced semiconductor that's free of freon and refrigerants, this car fridge is environmentally conscious. Plugs into an AC (home) outlet and comes with a 12V car adapter. It operates quietly with a 25dB sleep mode, ensuring minimal disturbance.
EXCELLENT AFTER-SALES SERVICE: We care about our customers. That's why we make sure to provide responsive and efficient customer service, assisting you with any queries or issues you might have with the product. Your satisfaction is our priority.

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Our Best Overall Choice

Best Choice

9.7

SECRETSBOX

SECRETSBOX Medication Cooler for Travel TSA Approved Medicine Cooler with 36-46℉ Digital Display Portable Mini Refrigerator for Medicine Diabetic Travel Case 1 Battery 20000mAh

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Material: Aluminum+ ABS+Eco-friendly Plastic
Core Technology: AUTO Thermoregulation System + Precise Temperature Control+Anti-freeze
Product Infor9.4x5.7x3.7 inches (Lx Wx H) Weight: 4.3lb
Warrantees: Lifetime Maintenance+ 3 Monthes Free Change or Money Back
Newly Anti Freeze Technology Designed: This medication cooler equipped with the latest high-tech chip, has non stop cooling effect. Cooling fast when the box turn on, will automatically shut off when the temperature drops to 36/2 and will automatically turn on when the temperature reach to 46/8. This allows for better refrigeration, prevents overheat and freezing. It can put 4 normal insulin pens and more injections,or you can use it as a mini fridge
Long Time Endurance and Power Alarming: The new patented diabetic insulin cooler travel case box contains 1 original rechargeable battery, 1 battery can last 9-12 hours in summer. When the TSA approved insulin cooler machine is low on power, the cooler box will intermittently beep to remind you to charge or replace the battery. In addition, the battery also can be used as power bank to charge other electronic device
4 Power Modes Suit All Charging Occasion: The new design cooler machine can be powered by the equipped battery, 5V power bank, USB or plug. It allow you to take plane, train or bus with our medicine cooling box. Suitable for home, office,travel,trip, driving, camping and all other activity. Our diabetic supplies travel cooling case will secure your medication safety at any time
Portable Handbag and Multifunctional Digital Display : The new designed insulin cooing case equipped with digital display that shows the inner temperature in real time and remaining power, also allow you to set a alarming to remind you to eat half an hour later after insulin injection. Anti-loss card,you can put your information on it. Hand strap allow you to take it up and down. Portable bag can be carried on shoulder or back. Fashionable in appearance and useful for privacy protection
How to Use and After Sell Service: Press the switch key or plug in the power supply, let the cooling box work for a while, open the lid, put in insulin pens or other medicines that need to be refrigerated, and close the lid. We promise free change or money back if you are not satisfied with our product within 90 days. Please contact us first if you have any issues when using the insulin cooling case, We offer lifetime after sell service about tech issues

Show Price

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