10 Best Oxymetazoline Hcl Nasal Spray of 2025

Main Highlights

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  ACTIVE INGREDIENT: This nasal spray contains oxymetazoline hydrochloride 0.05%, a nasal decongestant. Compare to the active ingredient in Afrin Original.
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  PURPOSE: This nasal spray temporarily relieves nasal congestion, sinus congestion and pressure due to the common cold, hay fever and upper respiratory allergies.
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  12 HOUR RELIEF: Amazon Basic Care Maximum Strength Nasal Spray provides fast, powerful congestion relief for allergies and colds for up to 12 hours.
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  FAST CONGESTION RELIEF: Provides fast and powerful nasal congestion relief for allergies and colds.
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  FAST-ACTING NASAL DECONGESTANT clears stuffy nose due to upper respiratory allergies and the common cold.

Main Highlights

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  NASAL DECONGESTANT SPRAY Contains 0.05% Oxymetazoline HCl to temporarily relieve nasal congestion from the common cold, hay fever, or upper respiratory allergies. Provides up to 12 hours of relief with a convenient nasal spray pump mist.
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  HELPS RELIEVE SINUS PRESSURE This nasal spray decongestant is formulated to temporarily reduce sinus pressure and swollen nasal membranes. Suitable for adults and children ages 6 to under 12, with adult supervision.
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  NON-DROWSY, NO DRIP NASAL SPRAY Quality non-drowsy, no-drip formula that wont run from the nose or down the throat. Designed for comfortable use to alleviate nasal congestion, cold, and allergy symptoms.
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  HOW TO USE - Shake well before use. 23 sprays per nostril every 1012 hours. Do not exceed 2 doses in 24 hours or for more than 3 days. Children under 6: Ask a doctor.
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  MAJOR PHARMACEUTICALS - At Major Pharmaceuticals, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering affordable, high-quality OTC and vitamin supplements, trusted by healthcare professionals and pharmacies across 50+ therapeutic categories.

Main Highlights

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  ACTIVE INGREDIENT: This nasal spray contains oxymetazoline HCl, a nasal decongestant and the doctor recommended adult nasal spray active ingredient (source: IQVIA physicians survey 2019), which compares to the active ingredient in Afrin No Drip. Offers maximum strength nasal congestion relief.
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  12 HOUR, MAXIMUM STRENGTH RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides 12 hours of maximum strength nasal congestion relief due to the common cold, hay fever and upper respiratory allergies.
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  FAST NASAL CONGESTION RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides fast and powerful relief for colds and allergies. Temporarily relieves sinus congestion and pressure.
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  NASAL RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides temporary nasal congestion relief by shrinking swollen nasal membranes so you can breathe more freely.
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  NO DRIP NASAL SPRAY: This cold and allergy relief nasal spray won't drip down your nose or throat. Severe congestion formula pump mist. Safety Sealed. This product is gluten free. Contains Menthol.

Main Highlights

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  ACTIVE INGREDIENT: This nasal spray contains oxymetazoline HCl, the #1 doctor recommended adult nasal spray active ingredient (of U.S. physicians surveyed by an independent market research firm). Compare to the active ingredient in Afrin No Drip.
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  SOOTHING 12 HOUR MAXIMUM STRENGTH RELIEF: Amazon Basic Care No Drip Nasal Spray, Oxymetazoline HCl provides 12 hours of maximum strength nasal congestion relief due to the common cold, hay fever and upper respiratory allergies.
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  FAST NASAL CONGESTION RELIEF: Amazon Basic Care No Drip Nasal Spray, Oxymetazoline HCl provides fast and powerful relief for colds and allergies. Temporarily relieves sinus congestion and pressure.
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  NASAL RELIEF: Amazon Basic Care No Drip Nasal Spray, Oxymetazoline HCl provides temporary nasal congestion relief by shrinking swollen nasal membranes so you can breathe more freely.
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  NO DRIP NASAL SPRAY: This cold and allergy relief nasal spray won't drip down your nose or throat. Nasal decongestant pump mist. This product is gluten free.

Main Highlights

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  POWERFUL CONGESTION RELIEF - Our nasal spray decongestant offers fast and powerful relief from nasal congestion and sinus pressure due to Allergies and Colds, providing a rapid solution to alleviate breathing discomfort.
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  MESS-FREE APPLICATION - With a no-drip mist pump applicator, this nose spray decongestant delivers effective relief without the inconvenience of the solution dripping down from the nose or throat.
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  LASTING EFFECTS - Don't let congestion mess up your day-to-day routine. Our sinus spray contains 0.05% oxymetazoline HCl and menthol, which provide 12 hours of relief from sinus congestion.
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  SUPERB VALUE - Each package contains two 1 fl. oz. bottles of our nasal spray congestion relief for adults. Keep one at home for your household, and bring one in your purse for when you're out and about.
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  YOUR WELLNESS IN MIND - We are committed to supplying premium wellness products to all our clients. Our decongestants for adults are made in a facility that complies with strict quality protocols.

Main Highlights

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  12 hour nasal relief
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  severe congestion
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  compare to afrin severe congestion
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  pump mist
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  anti-drip

Main Highlights

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  The information below is per-pack only
• 
  ACTIVE INGREDIENT: This nasal spray contains oxymetazoline hydrochloride 0.05%, a nasal decongestant. Compare to the active ingredient in Afrin Original.
• 
  PURPOSE: This nasal spray temporarily relieves nasal congestion, sinus congestion and pressure due to the common cold, hay fever and upper respiratory allergies.
• 
  12 HOUR RELIEF: Amazon Basic Care Maximum Strength Nasal Spray provides fast, powerful congestion relief for allergies and colds for up to 12 hours.
• 
  FAST CONGESTION RELIEF: Provides fast and powerful nasal congestion relief for allergies and colds.
• 
  FAST-ACTING NASAL DECONGESTANT clears stuffy nose due to upper respiratory allergies and the common cold.

Main Highlights

• 
  NASAL DECONGESTANT SPRAY Contains 0.05% Oxymetazoline HCl to temporarily relieve nasal congestion from the common cold, hay fever, or upper respiratory allergies. Provides up to 12 hours of relief with a convenient nasal spray pump mist.
• 
  HELPS RELIEVE SINUS PRESSURE This nasal spray decongestant is formulated to temporarily reduce sinus pressure and swollen nasal membranes. Suitable for adults and children ages 6 to under 12, with adult supervision.
• 
  NON-DROWSY, NO DRIP NASAL SPRAY Quality non-drowsy, no-drip formula that wont run from the nose or down the throat. Designed for comfortable use to alleviate nasal congestion, cold, and allergy symptoms.
• 
  HOW TO USE - Shake well before use. 23 sprays per nostril every 1012 hours. Do not exceed 2 doses in 24 hours or for more than 3 days. Children under 6: Ask a doctor.
• 
  MAJOR PHARMACEUTICALS - At Major Pharmaceuticals, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering affordable, high-quality OTC and vitamin supplements, trusted by healthcare professionals and pharmacies across 50+ therapeutic categories.

Main Highlights

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  Family Care Nasal Relief
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  Twelve bottles per order.

Main Highlights