10 Best Obagi Moisturizer And Serum of 2025

Tested and Reviewed: Top 10 Obagi Moisturizer And Serum deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Obagi Medical

Obagi Hydrate Facial Moisturizer – Non-Comedogenic Intensely Hydrating All Day Moisturizer that Combats Dryness with Tara Seed Extract, Shea Butter, Avocado Oil & Glycerin – All Skin Types – 1.7 oz

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Editor's bottom line:

“This obagi moisturizer and serum is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

All Day Moisturization: Obagi Hydrate Facial Moisturizer provides all day moisturization with an innovative hydration technology and natural ingredients such as shea butter, mango butter, avocado and glycerin, which further help combat dryness
For All Skin Types: Gentle, hypoallergenic and non-comedogenic, Obagi Hydrate is suitable for all skin types, including sensitive skin
Advanced Hydration: Tara Seed Extract matrix molecules help achieve and retain moisture and enhances your skins appearance and texture by allowing the epidermis to remain hydrated and to retain moisture
Dermatologist Tested, Physician Endorsed: Formulated with the purest, most effective ingredients, our portfolio of products are dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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Picked by 397 people today

9.5

Obagi Medical

Obagi Professional C Serum 20%, Vitamin C Facial Serum with Concentrated 20% L Ascorbic Acid for Normal to Oily Skin, 1.0 Fl Oz Pack of 1

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Main Highlights

Lighten skin discolorations, moisturize and hydrate skin to improve both texture and tone
Superior delivery system, resulting in greater penetration to all layers of the skin
Designed to stimulate collage to firm and support skin
Suitable for dry, sensitive or reactive skin types

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9.5

Obagi Medical

Obagi Hydrate Luxe Ultra-Rich Moisturizer – Night Face Cream Intensely Hydrates & Rejuvenates Complexion – Non-Comedogenic Skincare for Dry, Sensitive, or Aging Skin – 1.7 Oz

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Main Highlights

Overnight Restoration + Ultra-Rich Moisturization: Obagi Hydrate Luxe is specifically engineered with key biomimetic peptides; this non-comedogenic and hypoallergenic moisturizer provides ultra-rich moisturization and has a luxurious, balm-like texture
Ideal for Overnight Use: Non-comedogenic and hypoallergenic, use as part of your nightly skincare routine for long-lasting moisturization and a rejuvenated looking complexion
Advanced Hydration: Tara Seed Extract matrix molecules help achieve and retain moisture and enhances your skins appearance and texture by allowing the epidermis to remain hydrated and to retain moisture
Dermatologist Tested, Physician Endorsed: Formulated with the purest, most effective ingredients, our portfolio of products are dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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9.2

Obagi Medical

Obagi Hydrate Facial Moisturizer – Non-Comedogenic Intensely Hydrating All Day Moisturizer that Combats Dryness with Tara Seed Extract, Shea Butter & Avocado Oil – All Skin Types – 2-Pack, 1.7 oz ea

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Main Highlights

All Day Moisturization: Obagi Hydrate Facial Moisturizer provides all day moisturization with an innovative hydration technology and natural ingredients such as shea butter, mango butter, avocado and glycerin, which further help combat dryness
For All Skin Types: Gentle, hypoallergenic and non-comedogenic, Obagi Hydrate is suitable for all skin types, including sensitive skin
Advanced Hydration: Tara Seed Extract matrix molecules help achieve and retain moisture and enhances your skins appearance and texture by allowing the epidermis to remain hydrated and to retain moisture

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9.0

Obagi Medical

Obagi Daily Hydro-Drops Facial Serum – Hydrates & Helps Soften the Appearance of Fine Lines & Wrinkles – 1 oz

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Main Highlights

Hydrating Facial Serum: Our innovative Isoplentix Technology harnesses the power of Niacinamide, Abyssinian, & Hibiscus Oils in their purest forms to help soften the appearance of fine lines & wrinkles
Clinically Proven: 91% of participants said their skin felt smoother after the first use; results based on a blinded product usage test, data on file at Obagi Cosmeceuticals LLC
Dermatologist Tested, Physician Endorsed: Our portfolio of products is dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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8.8

Obagi Medical

Obagi Daily Hydro-Drops Hydrating Facial Serum for Dry Skin, Hypoallergenic, 1 fl oz- Pack of 2

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Main Highlights

Hydrating Facial Serum: Our innovative Isoplentix Technology harnesses the power of Niacinamide, Abyssinian, & Hibiscus Oils in their purest forms to help soften the appearance of fine lines & wrinkles
Clinically Proven: 91% of participants said their skin felt smoother after the first use; results based on a blinded product usage test, data on file at Obagi Cosmeceuticals LLC
Dermatologist Tested, Physician Endorsed: Our portfolio of products is dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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8.6

Obagi Medical

Obagi Professional-C 20% Vitamin C Serum – Helps Brighten Skin Tone and Minimize the Appearance of Fine Lines & Wrinkles – 0.42 oz

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Main Highlights

Supercharge Your Glow: Harnessing the power of L-ascorbic acid, the industry's gold standard of vitamin C our highest concentrated serum helps brighten skin tone, reduce signs of past skin damage and minimize the appearance of fine lines & wrinkles
Highly Concentrated Vitamin C: Known as the purest form of Vitamin C, L-ascorbic Acid is formulated at pH levels shown to optimize stability, permeability, and efficacy to help neutralize free radicals and fortify the skin barrier defenses
Clinically Tested: 91% of users reported skin appeared bright and more hydrated in a consumer study, data on file at Obagi Cosmeceuticals LLC
Dermatologist Tested, Physician Endorsed: Formulated with the purest, most effective ingredients, our portfolio of products are dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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8.3

Obagi Medical

Obagi ELASTIderm Lift Up & Sculpt Facial Moisturizer – Clinically Proven Anti-Aging Face Cream that Visibly Firms & Sculpts Facial Contours, & Reduces Fine Lines & Wrinkles with Peptides – 1.7 oz

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Main Highlights

Visibly Redefines & Transforms Facial Contours: Clinically proven to visibly lift and sculpt facial contours and restores the appearance of fullness
Advanced Ingredient Technology: Combines our Patented Bi-Mineral Contour Complex Zinc, Copper, and Malonic Acid with Polyglutamic Acid, a peptide found in dermal fillers known for its superior hydrating capabilities compared to Hyaluronic Acid
Clinically Proven: 100% of participants showed visible improvement in fine lines after 6 weeks and improved skin elasticity by up to 19% in as little as 3 weeks in a clinical test; data on file at Obagi Cosmeceuticals LLC
Dermatologist Tested, Physician Endorsed: Our portfolio of products are dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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8.1

Obagi Medical

Obagi Professional-C 20% Vitamin C Serum & Hydrate Facial Moisturizer Bundle – Brightens Skin Tone, Minimize the Appearance of Fine Lines & Wrinkles, & Combat Skin Dryness

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Main Highlights

SUPERCHARGE YOUR GLOW WITH VITAMIN C: This fast-absorbing serum strengthens antioxidant defenses for a radiant glow. Obagi Vitamin C Serum 20% harnesses the power of L-Ascorbic Acid to brighten skin tone, reduce dark spots, and minimize the appearance of fine lines and wrinkles
ALL-DAY MOISTURE: Hydrate has a lightweight formula with Tara Seed Extract, Shea Butter, and Mango Butter, clinically proven to improve skin moisture and combat dryness. It provides long-lasting hydration, reduces trans-epidermal water loss, and leaves skin nourished all day
DERMATOLOGIST TESTED, PHYSICIAN ENDORSED: Formulated with the purest, most effective ingredients, our portfolio of products are dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 YEARS OF TRANSFORMATIONAL SKINCARE: Obagi skincare originates in science and is backed by decades of clinical research leveraging cutting-edge technologies and pharma-grade ingredients that deliver transformative, visible results for all skin concerns, skin types, and skin tones
Serum c vitamin face acid la hyaluronic facial anti aging ageing retinol pearls derm korean natural rapid wrinkle lines clinical at home toner hydrating bio moisturizer skin care gel moisture hydrate moisturiser moisturization hydration dry dryness

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8.1

Obagi Medical

Obagi Daily Hydro-Drops Facial Serum & Rejuvenating Eye Gel Cream Set – 1oz Facial Serum Hydrates & Helps Soften the Appearance of Wrinkles & .5oz Eye Cream Instantly Brightens, Smooths, & Depuffs

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Main Highlights

Get Glowing Skin: This limited-edition Ultimate Hydration Duo includes our bestselling Daily Hydro-Drops Facial Serum & Rejuvenating Eye Gel Cream for a burst of lasting hydration that instantly delivers smoother, glowing skin
Facial Serum: Our innovative Isoplentix Technology harnesses the power of Niacinamide, Abyssinian, & Hibiscus Oils in their purest forms to help soften the appearance of fine lines & wrinkles; 91% of participants said skin felt smoother after the first use; results based on a blinded product usage test, data on file at Obagi Cosmeceuticals LLC
Eye Gel Cream: Instantly boost skins radiance, brightening the skin under the eyes while simultaneously refreshing the eye area with hydration that lasts for 24 hours; 100% of participants reported an immediate improvement in skin hydration after a single application; results based on a bio-instrumentation study, data on file at Obagi Cosmeceuticals LLC
Dermatologist Tested, Physician Endorsed: Our portfolio of products is dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
Over 35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

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Our Best Overall Choice

Best Choice

9.7

Obagi Medical

Obagi Hydrate Facial Moisturizer – Non-Comedogenic Intensely Hydrating All Day Moisturizer that Combats Dryness with Tara Seed Extract, Shea Butter, Avocado Oil & Glycerin – All Skin Types – 1.7 oz

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

All Day Moisturization: Obagi Hydrate Facial Moisturizer provides all day moisturization with an innovative hydration technology and natural ingredients such as shea butter, mango butter, avocado and glycerin, which further help combat dryness
For All Skin Types: Gentle, hypoallergenic and non-comedogenic, Obagi Hydrate is suitable for all skin types, including sensitive skin
Advanced Hydration: Tara Seed Extract matrix molecules help achieve and retain moisture and enhances your skins appearance and texture by allowing the epidermis to remain hydrated and to retain moisture
Dermatologist Tested, Physician Endorsed: Formulated with the purest, most effective ingredients, our portfolio of products are dermatologist tested and physician endorsed; thats why professionals trust us to provide superior skincare for their patients
35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, were proud to bring you effective & transformative solutions for every step of your skincare journey

Show Price

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