10 Best Non Drowsy Zyrtec of 2025

Tested and Reviewed: Top 10 Non Drowsy Zyrtec deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

GenCare

GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

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Editor's bottom line:

“This non drowsy zyrtec is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

FULL 24 HOUR RELIEF - Enjoy non drowsy allergy relief that lasts for a full day. Cetirizine HCL over the counter medication helps alleviate symptoms of indoor and outdoor allergies like hay fever, pollen, dust, pet dander and seasonal allergies.
BULK SAVINGS - Each bottle contains 200 individual ready to swallow caplets so that you and your family can always have allergy support on hand. Our pills have a convenient indentation slot if you want to break the pill up into two 5 mg tabs for less severe symptoms or quick relief. Compare to generic Zyrtec active ingredients.
FAST ITCH RELIEF - Cetirizine HCL is a powerful antihistamine that helps relieve and prevent itchy watery eyes, runny nose, congestion and an irritated itchy throat. If you suffer from hives, cetirizine HCL 10mg may help reduce the itching and appearance of hives on your skin and face.
NON DROWSY FORMULA - Unlike most allergy medications, Cetirizine HCL tablets are non drowsy and can be taken at any time of day. Directions: Adults and children 6 years and older; one 10 mg tablet once daily; do not take more than 10 mg tablet in 24 hours.
100% SATISFACTION GUARANTEE - You don't have to suffer through indoor or outdoor allergies anymore! Get full non drowsy 24 hour allergy relief now and enjoy our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers...Click Add-to-Cart, Buy Now or Subscribe & Save Today!

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Picked by 397 people today

9.5

Zyrtec

Zyrtec 24 Hour Allergy Medicine Tablets, Indoor & Outdoor Allergy Pills, Non Drowsy Antihistamine, 10 mg Cetirizine HCI, Relief from Runny Nose, Sneezing, Itchy & Watery Eyes, 75 ct

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Main Highlights

24-Hour Allergy Relief: Zyrtec tablets provide fast, all-day relief from runny nose, sneezing, itchy, watery eyes, and itchy throat; non-drowsy formula starts working within 1 hour to block indoor and outdoor allergens.
Active Ingredient Precision: Each cetirizine 10 mg tablet delivers prescription-strength antihistamine action to treat hay fever, tree pollen, dust, mold, pet dander, weeds, and grasses; easy-swallow tablets for ages 6 and up.
Indoor & Outdoor Protection: These allergy pills target common indoor irritants like dust, mold, and pet dander as well as outdoor triggers including tree pollen, weeds, and grasses; versatile relief all season long.
Age & Usage Clarity: Allergy medicine for adults and kids ages 6 and up, our non drowsy allergy medicine offers convenient once-daily dosing in a 75-count bottle; HSA/FSA eligible for cost-effective care.
Trusted Brand Assurance: From the #1 allergist-recommended OTC allergy medicine, Zyrtec delivers prescription-strength, fast-acting, 24-hour effectiveness with proven reliability so you can breathe easy day after day.

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9.5

Amazon Basic Care

Amazon Basic Care 24 Hour Allergy Relief, Cetirizine Hydrochloride Tablets, 10 mg, 300 Count (Packaging may vary)

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Main Highlights

ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care All Day Allergy is cetirizine hydrochloride, an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms Compare to the active ingredient of Zyrtec
24-HOUR ALLERGY RELIEF: Temporarily provides relief of symptoms due to hay fever or other upper respiratory allergies: runny nose, sneezing, itching of the nose or throat and itchy, watery eyes
INDOOR AND OUTDOOR ALLERGY RELIEF: Temporarily relieves common indoor and outdoor allergy symptoms
EFFECTIVE: Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg are original prescription strength and gluten free These allergy pills are an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms
UNDERSTANDING ALLERGIES: An allergy is a sensitivity to a substance that is normally harmless Flowers, trees, a family pet, or dust are examples of things that can cause an allergy These allergy pills provide up to 24 hours of temporary relief
Product may be manufactured in India or U.S.

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9.2

Zyrtec

Zyrtec 24 Hour Allergy Relief Tablets, Fast-Acting Allergy Medicine for Indoor & Outdoor Allergies, Cetirizine 10 mg Tablet Antihistamine, 30 ct Bottle & 3 Single-Dose Travel Packs Bundle Pack

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Main Highlights

Bundle convenience: Includes one 30-count bottle and three 1-count travel packs; perfect for home and on-the-go allergy relief tablets with 24-hour coverage for indoor and outdoor allergies, dust, pollen, pet dander, and more
Powerful formula: Each cetirizine 10 mg tablet delivers prescription-strength antihistamine relief; starts working at hour one and provides all-day symptom control for runny nose, sneezing, itchy, watery eyes, and itching of the nose or throat
Comprehensive symptom relief: Antihistamine tablets target common allergy symptoms including runny nose, sneezing, itchy, watery eyes, and itching of the nose or throat; effective for pollen allergy medicine needs and indoor or outdoor triggers
Adult and family use: Allergy medicine for adults and children ages 6 and up; cetirizine allergy pills are suitable for daily use and help manage seasonal and year-round allergies with a single dose for 24-hour protection
Trusted brand: Zyrtec is the #1 allergist-recommended brand among over-the-counter antihistamines; rely on cetirizine 10mg for effective, long-lasting relief from indoor and outdoor allergies, hay fever, and upper respiratory symptoms

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9.0

Zyrtec

Zyrtec 24 HR Indoor & Outdoor Allergy Liquid Gels Capsules, Cetirizine HCI Antihistamine, 40 ct

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Main Highlights

40-count bottle of Zyrtec 24 Hour Allergy Liquid Gels for relief of your worst indoor and outdoor allergy symptoms, including runny nose, sneezing, itchy, watery eyes, and itchy nose and throat
Prescription-strength allergy relief capsules start working hard at hour one and work twice as hard when you take it again the next day, for all-day allergy relief that stays strong
Each allergy liquid gel contains powerful Cetirizine HCl 10 mg (antihistamine) allergy medicine and effectively treats indoor allergies caused by dust, mold, and pet dander, as well as outdoor allergies caused by tree pollen, weeds, and grasses
Get effective allergy relief caused by hay fever and other upper respiratory allergies from the #1 allergist-recommended brand among over the counter oral antihistamines
This powerful anti-allergy medicine is suitable for adults and children six years and older, with one dose providing powerful, effective relief for a full 24 hours

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8.8

Zyrtec

Zyrtec 24 Hour Allergy Relief Tablets, Indoor & Outdoor Allergy Medicine with 10 mg Cetirizine Hydrochloride Antihistamine, Value Bundle of one, 90 ct Bottle & Three, 1 ct Travel Packs

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Main Highlights

Bundle pack convenience: Includes 90-count bottle and three 1-count travel packs for 93 total tablets; perfect for home or on-the-go allergy relief with trusted Zyrtec quality and value in every dose
24-hour allergy relief: Fast*-acting cetirizine hydrochloride 10mg antihistamine tablets provide powerful, prescription-strength relief from indoor and outdoor allergies, including pollen, dust, pet dander, and more. *Starts working at hour 1
Relief of Allergy Symptoms: Delivers effective symptom relief for runny nose, sneezing, itchy, watery eyes, and itching of the nose or throat; starts working at hour one and is suitable for adults and children ages 6 and up
Allergy pills for adults: Each cetirizine 10 mg tablet is an over-the-counter medication designed for long-lasting relief from hay fever, upper respiratory allergies, and seasonal or year-round allergy symptoms
FSA eligible & trusted brand: Zyrtec allergy relief tablets are FSA eligible and from the #1 doctor-recommended over-the-counter oral antihistamine brand; bundle pack offers convenience and value for managing allergies anytime, anywhere

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8.6

Zyrtec

Zyrtec 24 Hour Allergy Relief Tablets, Indoor & Outdoor Allergy Medicine for Adults with 5 mg Cetirizine Hydrochloride, Relief of Runny Nose, Sneezing, Itchy Eyes, Plus Dust, Mold & Pet Dander, 35 ct

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Main Highlights

Flexible dosing for symptom control: take one 5 mg tablet for mild allergy days or two tablets for more severe days; provides up to 24-hour relief of runny nose, sneezing, itchy, watery eyes, and itching of the nose or throat.
Indoor & outdoor relief: relieves allergies from dust, mold, and pet dander indoors (including dog and cat), plus tree pollen, weeds, and grasses outdoors; suitable for adults and children ages 6 and up to help maintain day-to-day comfort.
Antihistamine with cetirizine hydrochloride: each tablet contains 5 mg to treat hay fever and upper respiratory allergy symptoms; once-daily dosing with flexible 12 tablet guidance; consistent daily use may be needed to maintain 24-hour relief.
Age & dosing guidance: for ages 6 and up, take 1 tablet for mild symptoms or 2 tablets for more severe days with once-daily dosing; choose the dose that matches your symptom severity to manage indoor and outdoor allergy symptoms.
Travel-friendly 35-count bottle: compact size fits purses, backpacks, and medicine cabinets; contains cetirizine tablets for once-daily dosing so youre prepared at home or on the go through changing seasons and varied allergy conditions.

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8.3

Amazon Basic Care

Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 90 Count (Packaging may vary)

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Main Highlights

ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care All Day Allergy is cetirizine hydrochloride, an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms Compare to the active ingredient of Zyrtec
24-HOUR ALLERGY RELIEF: Temporarily provides relief of symptoms due to hay fever or other upper respiratory allergies: runny nose, sneezing, itching of the nose or throat and itchy, watery eyes
INDOOR AND OUTDOOR ALLERGY RELIEF: Temporarily relieves common indoor and outdoor allergy symptoms
EFFECTIVE: Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg are original prescription strength and gluten free These allergy pills are an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms
UNDERSTANDING ALLERGIES: An allergy is a sensitivity to a substance that is normally harmless Flowers, trees, a family pet, or dust are examples of things that can cause an allergy These allergy pills provide up to 24 hours of temporary relief
Product may be manufactured in India or U.S.

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8.1

ValuMeds

ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count)

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Main Highlights

Relieve Allergy Symptoms: Experience effective and long-lasting relief from allergies with ValueMeds Allergy Medicine. Our carefully formulated cetirizine hydrochloride pills provide powerful relief from a wide range of allergens, so you can enjoy life without the discomfort of allergies.
Provides 24-Hour Relief: With the same active ingredient as the leading brands, our generic allergy pills offer a more affordable solution without compromising on quality. Don't let allergies hold you back tackle them head-on with our reliable and effective cetirizine formula.
Non-Drowsy Formula: Say goodbye to drowsiness. Our non-drowsy allergy medicine allows you to stay alert and focused throughout the day, making it ideal for work, school, or any activity that demands your full attention. Finally, you can experience allergy relief without feeling sleepy or sluggish.
Allergy Relief for the Whole Family: Suitable for adults and children alike, our allergy medicine offers relief for the whole family. From kids to adults, everyone can benefit from the non-drowsy, long-lasting relief of cetirizine. Allergy symptoms won't stand a chance against our trusted formula.
Buy from a Trusted Brand: Trust in our brand's commitment to quality and efficacy. ValuMeds Cetirizine HCl is produced in a state-of-the-art facility, ensuring that each tablet is of the highest standard. With our brand's reputation and your satisfaction in mind, we bring you reliable relief from allergies.

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8.1

Zyrtec

Zyrtec 24 Hour Allergy Relief Tablets, Indoor and Outdoor Allergy Medicine with 10 mg Cetirizine HCl per Antihistamine Tablet, Bundle Pack, 60 ct + 3 ct Travel Packs, 63 Count

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Main Highlights

Bundle pack with one, 60-count bottle plus three, single travel packs of Zyrtec 24 Hour Allergy Tablets with cetirizine HCl for powerful relief of your worst allergy symptoms like runny nose, sneezing, itchy, watery eyes, & itchy nose & throat
This powerful antihistamine contains 10mg of cetirizine hydrochloride in each allergy relief tablet to treat indoor allergies caused by dust, mold, & pet dander, as well as outdoor seasonal allergies caused by ragweed, tree pollen, weeds, & grasses
From the #1 allergist-recommended brand among over-the-counter oral antihistamines, these allergy relief tablets provide powerful relief from your worst allergy symptoms, plus, relief from hay fever & other upper respiratory allergies
Suitable for those 6 years of age & older, this allergy relief medication provides powerful, effective relief from your allergy symptoms. Zyrtec works fast* at hour one & provides 24-hour relief for indoor & outdoor allergies
These prescription-strength cetirizine HCl allergy medicine tablets work fast* & stay strong by providing all-day relief from your allergies. Zyrtec Allergy Tabs are HSA and FSA eligible, check with your plan for complete coverage details

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Our Best Overall Choice

Best Choice

9.7

GenCare

GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

FULL 24 HOUR RELIEF - Enjoy non drowsy allergy relief that lasts for a full day. Cetirizine HCL over the counter medication helps alleviate symptoms of indoor and outdoor allergies like hay fever, pollen, dust, pet dander and seasonal allergies.
BULK SAVINGS - Each bottle contains 200 individual ready to swallow caplets so that you and your family can always have allergy support on hand. Our pills have a convenient indentation slot if you want to break the pill up into two 5 mg tabs for less severe symptoms or quick relief. Compare to generic Zyrtec active ingredients.
FAST ITCH RELIEF - Cetirizine HCL is a powerful antihistamine that helps relieve and prevent itchy watery eyes, runny nose, congestion and an irritated itchy throat. If you suffer from hives, cetirizine HCL 10mg may help reduce the itching and appearance of hives on your skin and face.
NON DROWSY FORMULA - Unlike most allergy medications, Cetirizine HCL tablets are non drowsy and can be taken at any time of day. Directions: Adults and children 6 years and older; one 10 mg tablet once daily; do not take more than 10 mg tablet in 24 hours.
100% SATISFACTION GUARANTEE - You don't have to suffer through indoor or outdoor allergies anymore! Get full non drowsy 24 hour allergy relief now and enjoy our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers...Click Add-to-Cart, Buy Now or Subscribe & Save Today!

Show Price

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