10 Best Microneedling Serum of 2025

Tested and Reviewed: Top 10 Microneedling Serum deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

ZealSea

ZealSea Hyaluronic Acid Serum for Face, Hydrating Microneedling Serum, EWG Certified for Sensitive Skin, Vegan Fragrance Free Non-Comedogenic Absorb Quickly, Pure Hyaluronic Acid Anti-Aging 1 Oz

Free Shipping

Editor's bottom line:

“This microneedling serum is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Ultimate Hydtrating SerumEWG Certified): Zealsea Patent 4D Hyaluronic Acid Serum for face delivers an intense hydration boost for a radiant, plump, and youthful look. This powerful Acido Hialuronico Serum keeps your skin soft and supple all day long
Safe & Hypoallergenic Microneedling Serum: Our Pure Hyaluronic Acid Serum combined with B5, is specially for microneedling. It deeply moisturizes and soothes the skin, enhancing skin's natural barrier. Perfect for maximizing the benefits of microneedling
No Harsh Ingredients: This moisturizing face serum is certified by authoritative EWG. It is crulety free, phenoxyethanol free, paraben free, fragrance free. Clean ingredients make this Acido Hialuronico Serum suitable for all skin type even sensitive skin
Potent Anti-Aging Hyaluronic Acid: This innovative ingredient delivers a multi-dimensional approach to hydration. With regular use, you can expect a noticeable improvement in skin texture and elasticity. Say goodbye to dryness and hello to a dewy glow
Praised By Thousands of Influencers: Zealsea hyaluronic acid serum for face is viral on social medium, popular with women,teenagers. A perfect gift for friends, family. Enjoy the high-quality face serum as a skincare routine. Indulge in yourself everyday

Show Price

Picked by 397 people today

9.5

BRÜUN

BRÜUN SC - Control Botanical Stem Cell Ampoule - Korean Serum Booster for Face and Body Skin Care Serum 1.18 fl.oz

Free Shipping

Main Highlights

Usage: Our 1.18 oz serum ampule is enough for multiple usage. This serum is for external use only. After using the ampule keep the Serum collector inserted in bottle.
Absorption: Due to its low molecular weight our serum absorbs into your skin naturally. You will feel comfortable and relaxed after applying our ampule on your face skin. (Non-Injectable)
Economical product: Do not waste money on expensive skin care. Our Serum is economical and will shows multiple results including fresh and smooth skin.
Aesthetic look: Our Skin care serum makes your skin look attractive and enhance the aesthetic and you will be visible from others.
Made in South Korea: Our product is made in South Korea and 100 percent cruelty free. No animal is harmed for its production also it is not tested on animals.

Show Price

9.5

CELDYQUE

Salmon DNA PDRN 120,000 ppm EGF Peptide Microneedling Serum w/Volufiline, Phyto PDRN 12%, Growth Factor - Anti-Aging Face Serum with Niacinamide, Hyaluronic Acid 1 Fl Oz Korean Skincare

Free Shipping

Main Highlights

12% - Formulated with 120,000 ppm PDRN (Sodium( Salmon DNA ) DNA 2% + Phyto PDRN Solution 10%), this high-dose regenerative complex revitalizes damaged skin, boosts cellular turnover, and restores firmness.
- - - Targets wrinkles, sagging, and dullness with EGF(Epidermal Growth Factor) peptides, Volufiline, and niacinamide 20,000 ppmsupporting collagen synthesis and improving elasticity for visibly younger-looking skin.
& - A hyaluronic acid complex, ceramides, and panthenol deliver multi-layer hydration while reinforcing the skins natural barrier against environmental stressors.
& - Lightweight, non-sticky texture designed for both MTS roller treatments and daily serumsabsorbs fast and layers perfectly under moisturizer or makeup.
- Uses lecithin-based liposome encapsulation to drive active ingredients deeper into the skin, maximizing results without irritation. Suitable for sensitive skin types.

Show Price

9.2

medicube

medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz

Free Shipping

Main Highlights

Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicubes Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

Show Price

9.0

BRÜUN

BRÜUN SD - Control Salmon DNA Ampoule - Micro Needling Korean Serum Booster for Face and Body to Use with and without Derma Pen Microneedling Skin Care Serum 1.18 fl.oz

Free Shipping

Main Highlights

Usage: Our 1.18 oz serum ampule is enough for multiple usage. After using the ampule keep the collector inserted in bottle. You can use this booster serum with micro needling derma roller and pen.
Absorption: When it is used with derma roller it absorbs deep in your skin and give you better result. You will feel comfortable and relaxed after applying our ampule on your face skin.
Economical product: Do not waste money on expensive skin care treatments and therapies. Our Serum is economical and will shows multiple results including fresh and smooth skin.
Aesthetic look: Our Skin care serum makes your skin look attractive and enhance the aesthetic of your face and you will be visible from others.
Made in South Korea: Our product is made in South Korea and 100 percent cruelty free. No animal is harmed for its production also it is not tested on animals.

Show Price

8.8

TRSTAY LUXE

TRSTAY LUXE Stem Cell & Salmon DNA PDRN Serum – Microneedling Aftercare Anti-Aging Face Serum with Peptides & Hyaluronic Acid – 1.5 mL × 30 Vials, Korean Skincare Formula

Free Shipping

Main Highlights

Hydrating & Firming Support Infused with multi-molecular Hyaluronic Acid and Salmon DNA (PDRN), this microneedling serum helps replenish moisture and supports the look of plump, supple skin.
Advanced Stem Cell Complex Formulated with botanical stem cell extracts to promote skin vitality, leaving the complexion looking smoother, more refreshed, and revitalized.
Multi-Peptide Anti-Aging Blend Includes Acetyl Hexapeptide-8, Palmitoyl Tripeptide-5, and Acetyl Tetrapeptide-2, helping to minimize the appearance of fine lines and support firmer-looking skin.
Powerful Antioxidant Blend Enriched with peptides, adenosine, and astaxanthin to help protect against environmental stressors and support a youthful, radiant appearance.
Soothing & Protective Care Enriched with Niacinamide, Ceramides, Panthenol, and Madecassoside, this ampoule helps strengthen the skin barrier and reduce visible signs of stress after cosmetic procedures.
Microneedling Aftercare Serum Single-use ampoule format ensures freshness, ideal for post-cosmetic procedures and daily anti-aging routines.

Show Price

8.6

medicube

medicube Salmon DNA PDRN Pink One Day Serum | 99% Salmon DNA PDRN Intensive Ampoule, Collagen, Glutathione, Hyaluronic Acid - Improves skin radiance | Korean skincare 0.05 fl.oz x 10e

Free Shipping

Main Highlights

99% High-Purity Salmon PDRN: Enhanced absorption with minimal residue due to its small particle size. Uniform and stable concentration ensures better absorption and more effective skincare benefits.
Exclusive medicube Formula for Uneven Skin Tone: Combines salmon roe extract for uneven skintone, ultra-small 285Da collagen (1/1000 the size of regular collagen) for improved elasticity, and glutathione & elastin for healthy, glass glow skin.
Hydrating & Radiance-Boosting Salmon DNA Ampoule: Improves skin density with 58.7% hydration increase immediately after use and a 38.8% boost in radiance.
One-Day Pink Drop Ampoule: Each dose is individually packaged in a convenient, single-use vial inspired by eye drops. This design ensures the stability of the intensive ampoule formula and delivers maximum efficacy with every application.
How to Use: Open the vial and apply the ampoule after toner in your skincare routine. If any product remains, reseal and use within one day for maximum freshness. For best results, use immediately after opening to preserve potency.

Show Price

8.3

medicube

medicube Exosome Shot Zero 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz

Free Shipping

Main Highlights

Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicubes Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

Show Price

8.1

VT COSMETICS

VT COSMETICS CICA Reedle Shot 100, Spicule Microneedling Serum for Pore Care & Exfoliation, Exosome, Centella Asiatica for Glass Skin, Skin Texture, Korean Liquid Skin Booster (1.69 Fl Oz / 50ml)

Free Shipping

Main Highlights

Spicule Microneedling Serum for Pore Care VT COSMETICS Reedle Shot 100 is a spicule microneedling serum designed to support pore care, gentle exfoliation, and improved skin texture by helping active ingredients absorb more effectively than traditional skincare serums with topical application alone.
Daily Microneedling Exfoliating Serum Reedle Shot 100 delivers mild microneedling stimulation suitable for daily use, making it an ideal exfoliating serum for beginners seeking smoother skin, refined pores, and visible skin texture improvement without the harshness of professional microneedling treatments.
CICA, Centella Asiatica & Exosome Care Formulated with Centella Asiatica (CICA) and exosome-based ingredients to help calm sensitive skin, support the skin barrier, and maintain hydration while using a microneedling skincare product that focuses on the appearance of refined pores and skin texture refinement.
Glass Skin Texture Booster This Korean skincare liquid skin booster helps improve dull skin, uneven texture, and roughness by promoting gentle exfoliation and skin turnover, supporting a smooth, radiant glass skin appearance commonly associated with K-beauty skincare routines.
Korean Skincare for All Skin Types Suitable for oily, dry, and combination skin types, this microneedling face serum can be applied after cleansing and followed by moisturizer, providing an easy at-home Korean skincare solution for pore care, skin smoothing, and texture refinement.
Usage Tips & Precautions For best results, apply a small amount to cleansed skin and gently massage until absorbed, then follow with moisturizer; a patch test is recommended before first use, and discontinue use if irritation occurs, especially for sensitive skin types.

Show Price

8.1

medicube

medicube PDRN Pink Peptide Serum with Salmon DNA | Pink Glow Serum with Peptides & Niacinamide for Hydration & Firm-Looking Skin | Uneven Tone Care | Korean Skincare, 1.01 fl. Oz

Free Shipping

Main Highlights

KOREAN GLASS GLOW SKIN: This pink glow serum targets dull skin and boosts elasticity, helping to prevent future breakouts while enhancing the skin's glow and resilience.
SALMON DNA PDRN: Salmon DNA PDRN is a form of DNA extracted from salmon. It stimulates skin renewal and repair, giving your skin a clearer, more luminous complexion. It promotes a more even skin tone and a natural glow by improving skin health.
KEY INGREDIENTS: Containing Salmon DNA PDRN, five types of peptide complex, niacinamide, adenosine, and Ocimum Sanctum (Holy Basil) leaf extract, this formula provides effective care for uneven skin tone and elasticity.
LONG LASTING HYDRATION: Strengthens the skins barrier function, enhancing its resistance to external aggressors and pollutants. It provides deep hydration and smooths skin texture.
MILD FORMULA LIGHT TEXTURE: The formula is mild and gentle for all skin typesgentle enough to be used daily. Dermatologist-tested, low-irritating, and free from gluten and artificial colors.

Show Price

Our Best Overall Choice

Best Choice

9.7

ZealSea

ZealSea Hyaluronic Acid Serum for Face, Hydrating Microneedling Serum, EWG Certified for Sensitive Skin, Vegan Fragrance Free Non-Comedogenic Absorb Quickly, Pure Hyaluronic Acid Anti-Aging 1 Oz

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Ultimate Hydtrating SerumEWG Certified): Zealsea Patent 4D Hyaluronic Acid Serum for face delivers an intense hydration boost for a radiant, plump, and youthful look. This powerful Acido Hialuronico Serum keeps your skin soft and supple all day long
Safe & Hypoallergenic Microneedling Serum: Our Pure Hyaluronic Acid Serum combined with B5, is specially for microneedling. It deeply moisturizes and soothes the skin, enhancing skin's natural barrier. Perfect for maximizing the benefits of microneedling
No Harsh Ingredients: This moisturizing face serum is certified by authoritative EWG. It is crulety free, phenoxyethanol free, paraben free, fragrance free. Clean ingredients make this Acido Hialuronico Serum suitable for all skin type even sensitive skin
Potent Anti-Aging Hyaluronic Acid: This innovative ingredient delivers a multi-dimensional approach to hydration. With regular use, you can expect a noticeable improvement in skin texture and elasticity. Say goodbye to dryness and hello to a dewy glow
Praised By Thousands of Influencers: Zealsea hyaluronic acid serum for face is viral on social medium, popular with women,teenagers. A perfect gift for friends, family. Enjoy the high-quality face serum as a skincare routine. Indulge in yourself everyday

Show Price

Deals are Live

Special Amazon deal ends in: