10 Best Kleenex Ultra Soft Hypoallergenic Tissues of 2025

Tested and Reviewed: Top 10 Kleenex Ultra Soft Hypoallergenic Tissues deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Kleenex

Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box, 3-Ply, Packaging May Vary

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Editor's bottom line:

“This kleenex ultra soft hypoallergenic tissues is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

WHAT'S INCLUDED 8 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 80 tissues per box (640 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

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Picked by 397 people today

9.5

Kleenex

Kleenex Ultra Soft Facial Tissues, 8 Flat Boxes, 180 Tissues per Box, 3-Ply, Packaging May Vary

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Main Highlights

WHAT'S INCLUDED 8 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 180 tissues per box (1,440 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

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9.5

Kleenex

Kleenex Ultra Soft Facial Tissues, 4 Cube Boxes, 60 Tissues per Box, 3-Ply (240 Total), Packaging May Vary

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Main Highlights

WHAT'S INCLUDED 4 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 60 tissues per box (240 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

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9.2

Kleenex

Kleenex Ultra Soft Facial Tissues, 3 Flat Boxes, 120 Tissues per Box, 3-Ply (360 Total), Packaging May Vary

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Main Highlights

WHAT'S INCLUDED 3 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 120 tissues per box (360 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

Show Price

9.0

Kleenex

Kleenex Ultra Soft Facial Tissues, 18 Flat Boxes, 120 Tissues per Box, 3-Ply (2,160 Total), Packaging May Vary

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Main Highlights

WHAT'S INCLUDED 18 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 120 tissues per box (2,160 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

Show Price

8.8

Kleenex

Kleenex Ultra Soft Facial Tissues, 1 Flat Box, 120 Tissues per Box, 3-Ply, Packaging May Vary

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Main Highlights

1 FLAT BOX: Each box of Kleenex Ultra Soft contains 120 tissuespackaging may vary from what is shown.
SOFT FACIAL TISSUE: Americas #1 preferred Ultra Tissue (vs Ultra national brands) softly comforts skin with 3 thick layers.
3-LAYER FACIAL TISSUE: 3 thick layers to comfort face and help protect hands for everyday use and during allergy season, back-to-school season, and cold and flu season.
HYPOALLERGENIC FACIAL TISSUE: Each box of hypoallergenic facial tissues has designs that can fit your homecontains various colors and designs.
GET FACIAL TISSUES DELIVERED: Skip the store and get Kleenex Ultra Soft delivered right to your door.

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8.6

Kleenex

Kleenex Ultra Soft Facial Tissues, 4 Flat Boxes, 180 Tissues per Box, 3-Ply, Packaging May Vary

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Main Highlights

WHAT'S INCLUDED 4 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 180 tissues per box (720 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

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8.3

Kleenex

Kleenex® Ultra Soft 3-Ply Unscented Tissues, 8-1/4" x 8-7/16", 65 Per Box, Pack Of 4 Boxes

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Main Highlights

Enjoy softness and strength when you choose the Kleenex Ultra Soft 3-Ply Unscented Tissues. These hypoallergenic tissues are great for those with sensitive skin and feature a dependable 3-ply design.
Ultra soft to feel good against the skin.
3-ply design offers dependable strength.
Helps provide relief for sore noses and sensitive skin.

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8.1

Kleenex

Kleenex Expressions Ultra Soft Facial Tissues, 8 Flat Boxes, 120 Tissues per Box, 3-Ply, Packaging May Vary

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Main Highlights

This product has been discontinued by the manufacturer
Each box of Kleenex Expressions Ultra Soft contains 120 tissues
Americas #1 preferred Ultra Tissue (vs Ultra national brands) softly comforts skin with 3 thick layers

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8.1

Kleenex

Kleenex Ultra Soft Facial Tissues - Pack of 12 Cube Tissue Boxes

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Main Highlights

Gentle for your skin - Sick of rough tissues making your cold feel even worse? Give your skin the comfort you deserve with Kleenex Ultra Soft tissues.
Silky soft and luxurious - Kleenex Ultra Soft tissues are one of the UK's softest facial tissues. Designed with luxury in mind Kleenex Ultra Soft Tissues will leave your skin feeling beautiful
From a brand you can trust Kleenex Ultra Soft tissues are made by Kimberly-Clark, the manufacturer of Andrex toilet roll and Huggies baby wipes - so you can be sure that youre buying the highest quality product.
A sustainable choice Out tissue boxes now made with paper baffle meaning they are fully recyclable, making Kleenex UltraSoft Tissues a sustainable choice.
Buy a pack of 12 cube boxes - Bulk buy 12 cube boxes of our tissues so you and your family never run out when you need them most.

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Our Best Overall Choice

Best Choice

9.7

Kleenex

Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box, 3-Ply, Packaging May Vary

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

WHAT'S INCLUDED 8 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 80 tissues per box (640 tissues total)
FOR THE BIG AND LITTLE MOMENTS Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
SILKY SOFTNESS These facial tissues are made with 3 layers of silky-soft strength thats gentle on watery eyes and runny noses for an extra bit of comfort when you need it
ALLERGIST APPROVED Our tissues are hypoallergenic, dermatologist tested, and allergist approved
SAVE YOUR TOILET PAPER When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
THE #1 ULTRA TISSUE* Were the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

Show Price

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