10 Best Hypoallergenic Baby Formula of 2025

Tested and Reviewed: Top 10 Hypoallergenic Baby Formula deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 19.8 Oz Can

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Editor's bottom line:

“This hypoallergenic baby formula is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

HELPS TO EASE COLIC: Delivers Clinically-Proven Relief when managing colic due to cows milk allergy for a happier, better-rested baby & mom.Amino acid-based
FAST RELIEF NOW: As early as the first feeding, with 90% of infants improving within 48 hours
INCLUDES LGG: The most extensively studied probiotic for allergy management and supporting the digestive health of your baby
BRAIN SUPPORT: Nutramigen is a gentle, lactose free baby formula that has important nutrients found in breast milk such as Omega-3 DHA, ARA, and Choline that provide brain support
IMMUNE SUPPORT: Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response

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Picked by 397 people today

9.5

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz Can

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Main Highlights

HELPS TO EASE COLIC: Delivers Clinically-Proven Relief when managing colic due to cows milk allergy for a happier, better-rested baby & mom.Amino acid-based
FAST RELIEF NOW: As early as the first feeding, with 90% of infants improving within 48 hours
INCLUDES LGG: The most extensively studied probiotic for allergy management and supporting the digestive health of your baby
BRAIN SUPPORT: Nutramigen is a gentle, lactose free baby formula that has important nutrients found in breast milk such as Omega-3 DHA, ARA, and Choline that provide brain support
IMMUNE SUPPORT: Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response

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9.5

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 12.6 Oz Can

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Main Highlights

Fast relief NOW. Fewer allergy challenges LATER
Starts to manage colic in as early as the first feeding, with 90% of infants improving within 48 hours*+
Clinically demonstrated to help reduce future allergy challenges
Helps babies return to consuming milk protein without an allergic response

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9.2

NUTRICIA PEPTICATE

Pepticate Baby Formula, Hypoallergenic Powdered Infant Formula for Cow Milk Allergy, with Omega 3 DHA, ARA, Iron & Prebiotics, 13.2oz

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Main Highlights

HYPOALLERGENIC INFANT FORMULA: Pepticate is the leading extensively hydrolyzed infant formula (eHF) in Europe with over 30 years of experience in managing infants with cow milk allergy (CMA)
COW MILK ALLERGY SYMPTOM MANAGEMENT: Clinically shown to be effective in the nutritional management of CMA. Helps to provide relief from symptoms of CMA, such as eczema and colic
INSPIRED BY BREAST MILK: Pepticate is inspired by key components found in breast milk, including prebiotic oligosaccharides to support infant digestive health and immune system development, nucleotides to help support the immune system, and DHA and ARA to promote brain and eye development
MADE IN EUROPE: Nutritionally complete, safe, and well tolerated formula sold in over 75 countries
#1 EXTENSIVELY HYDROLYZED FORMULA (eHF) in Europe: Pepticate is the #1 eHF recommended by UK pediatricians (Most recommended brand on a 2022 survey of UK GPs, pediatricians, and dieticians: n =206)

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9.0

Similac

Similac Alimentum With 2'-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic Due to Protein Sensitivity, Baby Formula Powder, 19.8-oz Value Can

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Main Highlights

GET MORE REWARDS POINTS: Scan the MySimilac QR code on select products to earn points toward a Reward
HYPOALLERGENIC: Our formula contains a milk protein that is broken down into tiny pieces to virtually eliminate allergic reactions in most babies who are allergic to cows milk protein
START FEELING BETTER TODAY*: Similac Alimentum starts reducing colic symptoms due to protein sensitivity within 24 hours in most infants*
HAS AN IMMUNE-NOURISHING INGREDIENT: First and only hypoallergenic formula with 2'-FL HMO, an immune-nourishing ingredient
ALSO AVAILABLE IN CONVENIENT READY TO FEED: Great for on-the-go and late-night feeding; no mixing required
SIMILAC IS THE #1 INFANT FORMULA BRAND FED IN HOSPITALS
EBT ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits in select stores. The SNAP name is a service mark of the US Department of Agriculture. The USDA does not endorse any goods, services, or enterprises

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8.8

Similac

Similac Alimentum with 2'-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic Due to Protein Sensitivity, Ready-to-Feed Baby Formula, 8-fl-oz Bottle, Pack of 24

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Main Highlights

GET MORE REWARDS POINTS: Scan the MySimilac QR code on select products to earn points toward a bonus offer
HYPOALLERGENIC: Our formula contains a milk protein that is broken down into tiny pieces to virtually eliminate allergic reactions in most babies who are allergic to cows milk protein
START FEELING BETTER TODAY: Similac Alimentum starts reducing colic symptoms due to protein sensitivity within 24 hours in most infants
WITH AN IMMUNE-NOURISHING INGREDIENT: First and only hypoallergenic formula with 2'-FL HMO, an immune-nourishing ingredient
SIMILAC IS THE #1 INFANT FORMULA BRAND FED IN HOSPITALS
EBT ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits in select stores. The SNAP name is a service mark of the US Department of Agriculture. The USDA does not endorse any goods, services, or enterprises

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8.6

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz, 4 Count

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Main Highlights

HELPS TO EASE COLIC: Delivers Clinically-Proven Relief when managing colic due to cows milk allergy for a happier, better-rested baby & mom.Amino acid-based.
FAST RELIEF NOW: As early as the first feeding, with 90% of infants improving within 48 hours
INCLUDES LGG: The most extensively studied probiotic for allergy management and supporting the digestive health of your baby
BRAIN SUPPORT: Nutramigen is a gentle, lactose free baby formula that has important nutrients found in breast milk such as Omega-3 DHA, ARA, and Choline that provide brain support
IMMUNE SUPPORT: Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response

Show Price

8.3

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Concentrated Liquid, 8 Fl Oz, 24 Bottles

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Main Highlights

HELPS EASE YOUR LITTLE ONES COLIC: Delivers clinically proven relief when managing colic due to cows milk allergy for a happier, better-rested baby and mom
GENTLE, FAST RELIEF: As early as the first feeding, many babies experience improvement within just 48 hours a comforting solution for your little one
NOURISHING BRAIN DEVELOPMENT: Nutramigen, a gentle, lactose-free formula, has omega-3 DHA, ARA, and choline to support your baby's growing brain
IMMUNITY SUPPORT: Help your baby's immune system adapt to standard milk formula
READY-TO-FEED AT ANY TIME: Convivence with complete nutrition for your baby
TRUSTED BY PEDIATRICIANS : Nutramigen is the 1 Trusted Hypoallergenic Formula Brand By Pediatricians
SNAP ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits
SUBSCRIBE and SAVE: Choose Subscribe and Save for additional savings and convenience

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8.1

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 19.8 Oz, 4 Count

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Main Highlights

HELPS TO EASE COLIC: Delivers Clinically-Proven Relief when managing colic due to cows milk allergy for a happier, better-rested baby & mom
FAST RELIEF NOW: As early as the first feeding, with 90% of infants improving within 48 hours
INCLUDES LGG: The most extensively studied probiotic for allergy management and supporting the digestive health of your baby
BRAIN SUPPORT: Nutramigen is a gentle, lactose free baby formula that has important nutrients found in breast milk such as Omega-3 DHA, ARA, and Choline that provide brain support
IMMUNE SUPPORT: Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response

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8.1

Gerber

Extensive HA® Hypoallergenic Infant Formula with Iron, DHA & Probiotics, 14.1 oz

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Main Highlights

CLINICALLY PROVEN TO BE HYPOALLERGENIC: Extensive HA is designed for babies with cows milk protein allergy (CMPA);
HIGH QUALITY PROTEIN: Contains 100% whey protein broken down into tiny pieces designed to be well-tolerated by most babies with CMPA and ultra-filtered for low residual allergenicity
SUPPORT FOR TINY TUMMIES: Extensive HA is the only hypoallergenic formula made with probiotic B lactis; a probiotic similar to those found in breast milk to support digestive health
QUALITY FROM BRAIN TO BELLY: Complete nutrition for baby plus DHA; DHA is recommended by experts for brain and eye development
HELPS EASE FUSSINESS AND GAS: This lactose-free sensitive baby formula helps ease tummy troubles associated with lactose intolerance

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Our Best Overall Choice

Best Choice

9.7

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 19.8 Oz Can

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

HELPS TO EASE COLIC: Delivers Clinically-Proven Relief when managing colic due to cows milk allergy for a happier, better-rested baby & mom.Amino acid-based
FAST RELIEF NOW: As early as the first feeding, with 90% of infants improving within 48 hours
INCLUDES LGG: The most extensively studied probiotic for allergy management and supporting the digestive health of your baby
BRAIN SUPPORT: Nutramigen is a gentle, lactose free baby formula that has important nutrients found in breast milk such as Omega-3 DHA, ARA, and Choline that provide brain support
IMMUNE SUPPORT: Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response

Show Price

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