10 Best Hydrolyzed Protein Cat Food of 2025

Tested and Reviewed: Top 10 Hydrolyzed Protein Cat Food deals with expert ratings from 8.1 to a perfect 10

September 2025 Edition

Editor's Choice

9.7

HILL'S PRESCRIPTION DIET

Hill's Prescription Diet z/d Skin/Food Sensitivities Wet Cat Food, Veterinary Diet, 5.5 oz. Cans, 24-Pack

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Editor's bottom line:

“This hydrolyzed protein cat food is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Hill's Prescription Diet z/d Food Sensitivities Canned Cat Food is specially formulated by Hills nutritionists and veterinarians to support your cats food sensitivities
Helps remove food related causes of skin irritation
Very tasty hydrolyzed animal protein designed to help avoid common food allergens
Promotes a healthy skin barrier
Natural fiber to help normalize stool

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Picked by 287 people today

9.5

Generic

Hill- s z/d Skin/Food Sensitivities Hydrolyzed Protein Dry Cat Food 8.5 lb

Main Highlights

Hill- s z/d Skin/Food Sensitivities Hydrolyzed Protein Dry Cat Food 8.5 lb

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9.5

Blue Buffalo

Blue Buffalo Natural Veterinary Diet HF Hydrolyzed for Food Intolerance Dry Cat Food, Veterinarian Prescription Required, Salmon, 7-lb. Bag

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Main Highlights

REAL MEAT FIRST: This Blue Buffalo dry cat food is made with real hydrolyzed salmon as the first ingredient
VETERINARY-PRESCRIBED FORMULA: Formulated for cats with special dietary needs, this dry cat food is packed with nutrition and flavor
IDEAL FOR CATS WITH FOOD SENSITIVITIES: Features easily digestible hydrolyzed ingredients for cats with food intolerance
HEALTHY, WHOLESOME INGREDIENTS: This natural cat food is made with no chicken (or poultry) by-product meals, and no corn, wheat, or soy
Contains: One (1) 7-lb. bag of BLUE Natural Veterinary Diet HF Hydrolyzed for Food Intolerance Dry Cat Food, Salmon
ENHANCED IMAGERY: We have enhanced our digital product packaging to highlight our products ingredients and essential benefits; While the physical packaging will differ slightly, all information is accurate

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9.2

Royal Canin

Royal Canin Veterinary Diet Feline Hydrolyzed Protein Adult HP Dry Cat Food, 12 oz

Main Highlights

Helps reduce skin and GI reactions that may be a result of sensitivities to common proteins found in pet foods
Helps minimize risk of reaction with proteins that are broken down to a size thats less likely to be recognized by the immune system
Reinforces the skin barrier with essential nutrients to support healthy skin in cats with skin sensitivity and irritation
Helps support healthy digestion with an exclusive blend of fibers and prebiotics

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9.0

HILL'S PRESCRIPTION DIET

Hill's Prescription Diet z/d Skin/Food Sensitivities Dry Cat Food, Veterinary Diet, 4 lb. Bag

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Main Highlights

Hill's Prescription Diet z/d Food Sensitivities Dry Cat Food is specially formulated by Hills nutritionists and veterinarians to avoid causes of food sensitivities
Helps remove food related causes of skin irritation
Very tasty hydrolyzed animal protein designed to help avoid common food allergens
Promotes a healthy skin barrier
Natural fiber to help normalize stool

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8.8

Royal Canin

Royal Canin Digestive Care Dry Cat Food, 6 lb bag

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Main Highlights

FOR CATS WITH SENSITIVE STOMACHS: Royal Canin Digestive Care Dry Cat Food is formulated for cats 1 year and older with sensitive stomachs
HEALTHY DIGESTION: An optimal blend of prebiotics and dietary fibers promotes digestive health
OPTIMAL STOOL: This precise diet is proven to be effective after 10 days with over 95% healthy stool quality
SPECIALIZED KIBBLE: Exclusive ring-shaped kibble encourages slower eating to help support healthy digestion
MIX WITH WET FOOD: Perfect complement to Royal Canin Digest Sensitive Wet Cat Food formulas

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8.6

Natural Balance

Natural Balance Limited Ingredient Adult Grain-Free Dry Cat Food, Reserve Duck & Green Pea Recipe, 10 Pound (Pack of 1)

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Main Highlights

DUCK IS THE SINGLE ANIMAL PROTEIN SOURCE providing essential protein and amino acids to help maintain strong muscles; Green Peas are included as a grain-free source of fiber to help support digestive health; Contains (1) 10-Pound Bag
WITH SENSITIVE PETS IN MIND weve carefully chosen a simplified list of premium ingredients to help support a healthy coat, skin & digestive system; made with a single animal protein source, and no added grain, soy, gluten, or artificial colors or flavors
NUTRIENTS FROM OUR GREEN PEA & DUCK CAT FOOD RECIPE crafted with nutritious ingredients such as green peas and fish oil; Complete and balanced with essential nutrients to help maintain your cat's healthy immune system
NUTRITION FOR EVERY TYPE OF CAT Any cat can enjoy our delicious recipes, not just cats with sensitive stomachs, irritable skin or allergies; Our purposefully crafted formulas reduce the number of ingredients without sacrificing taste or nutrition
SAFETY & TRANSPARENCY Natural Balance's 'Feed with Confidence' program tests every batch of food from start to finish, ensuring safety with every bite; Validate bag on our site or call our Customer Care Team of Registered Veterinary Technicians

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8.3

Pro Plan Veterinary Diets

Purina Pro Plan Veterinary Diets HA Hydrolyzed Feline Formula Dry Cat Food - 4 lb. Bag

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Main Highlights

Sensitive stomach cat food containing hydrolyzed protein sources
Hydrolyzed protein cat food includes a single carbohydrate source
Highly digestible Purina Pro Plan Veterinary Diets cat food formula to promote optimal nutrient absorption
Great-tasting Purina Pro Plan Veterinary Diets dry cat food formula featuring high-quality protein and antioxidants to support immune health
St/Ox Defense: This cat kibble promotes a urinary environment unfavorable to the development of both struvite and calcium oxalate crystals

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8.1

Instinct

Instinct Limited Ingredient Diet, Natural Dry Cat Food, Grain Free Recipe - Real Rabbit, 4.5 lb. Bag

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Main Highlights

GRAIN FREE CAT FOOD FOR CATS WITH SENSITIVITIES: Instinct Limited Ingredient cat food is made with 1 protein & 1 vegetable. No grain, dairy, eggs, chicken, beef, fish, sweet potato, potato, chickpeas, corn, wheat, soy, artificial colors or preservatives.
NATURAL CAT FOOD WITH FARM RAISED RABBIT: Crafted for cats with food allergy, our Limited Ingredient Diet is made with simple ingredients like farm raised rabbit, a healthy, easily digestible protein that provides all the essential amino acids.
THE FIRST RAW COATED KIBBLE: Instinct Limited Ingredient dry cat food is cat food where every piece of kibble is coated in freeze dried raw for nutrition and taste. Delicious, healthy flavor that cats to kittens crave.
POWER OF RAW INGREDIENTS: Our cat food is made with the pure, real nutrition of raw. Raw is natural, made from real meat & whole food ingredients, protein packed & minimally processed. Made in the USA with the finest ingredients from around the world.
OUR BEST CAT FOOD FOR ALLERGIES: We craft dry & wet cat food from real ingredients. Compare Instinct to Blue Buffalo, Fancy Feast, Hills Science Diet, Royal Canin, Rachel Ray, Natural Balance, Merrick, Purina One, Friskies, Wellness, Iams, Beyond & Weruva

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Best Value

8.1

Save 5%

Purina ONE

Purina ONE Sensitive Stomach, Sensitive Skin, Natural Dry Cat Food, +Plus Sensitive Skin and Stomach Formula - 7 lb. Bag

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Main Highlights

Real turkey is the first ingredient in our high protein cat food to help support strong muscles, including a healthy heart in adult cats
Made for cats with sensitive systems, this Purina ONE sensitive stomach cat food features an easily digestible formula with added prebiotic fiber
Crunchy cat food with calcium supports strong teeth and healthy gums, and four antioxidant sources help support a healthy immune system
With deliciously crunchy bites, this turkey cat food delivers a great taste and is made with no artificial flavors or preservatives
Purina sensitive skin and stomach cat food is crafted in Purina-owned, U.S. facilities

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Our Best Overall Choice

Best Choice

9.7

HILL'S PRESCRIPTION DIET

Hill's Prescription Diet z/d Skin/Food Sensitivities Wet Cat Food, Veterinary Diet, 5.5 oz. Cans, 24-Pack

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Hill's Prescription Diet z/d Food Sensitivities Canned Cat Food is specially formulated by Hills nutritionists and veterinarians to support your cats food sensitivities
Helps remove food related causes of skin irritation
Very tasty hydrolyzed animal protein designed to help avoid common food allergens
Promotes a healthy skin barrier
Natural fiber to help normalize stool

Show Price

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Pur-ina HA Hydrolyzed Dry Cat Food 4 lb

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Dr. Elsey's Cleanprotein Salmon Formula Dry Cat Food, 6.6 Lb

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Royal Canin Veterinary Diet Feline Multifunction Renal Support + Hydrolyzed Protein Dry Cat Food, 6.6 lb

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