10 Best Gel Eye Drops Preservative Free of 2025

Tested and Reviewed: Top 10 Gel Eye Drops Preservative Free deals with expert ratings from 8.1 to a perfect 10

July 2025 Edition

Editor's Choice

9.7

TheraTears

TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Vials, 30 Count (Pack of 2)

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Editor's bottom line:

“This gel eye drops preservative free is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

IMMEDIATE DRY EYE RELIEF: TheraTears Lubricating Liquid Gel Eye Drops provide immediate, long-lasting relief of dry eye symptoms
HYDRATING EYE DROPS: TheraTears Nighttime dry eye drops have 4X the lubrication* for a subtly thicker, extra hydrating experience for tired, dry eyes while you sleep; *vs. TheraTears Original
PRESERVATIVE FREE EYE DROPS: These eye drops for dry eyes are formulated with the 5 vital electrolytes found in natural tears and are individually sealed for preservative free eye drops in a single-use vial
CREATED BY AN OPHTHALMOLOGIST: TheraTears was created by an ophthalmologist after 18 years of research for a one-of-a-kind eye drop
DOCTOR RECOMMENDED: Doctor recommended and created to bring balance and hydration to dry eyes

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Picked by 334 people today

9.5

Save 20%

Refresh

Refresh Optive Gel Drops Lubricant Eye Gel For Dry Eyes, 0.33 Oz Sterile

20% OffFree Shipping

Main Highlights

Extended relief plus protection for dry, irritated eyes
Our most comprehensive gel formula
Anytime relief, day or night
Feels like a drop but works like a gel for lasting comfort
Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
#1 doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

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9.5

Save 35%

Refresh

Refresh Celluvisc Lubricant Eye Gel Preservative-Free Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

35% OffFree Shipping

Main Highlights

Original strength gel formula
Relieves dry, burning, irritated eyes
Alleviates discomfort
Keeps eyes feeling better longer
doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey

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9.2

Save 20%

iVIZIA

iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary

20% OffFree Shipping

Main Highlights

Your Dry Eyes Deserve Better: Thicker formula for overnight use, our gel provides more lubrication and moisture than our daytime formula and is ideal to relieve severe dry eye symptoms.
Free of Irritating Preservatives: Sterile, preservative-free, and can be used before or after eye surgery.
Sterile Single-Use Vials: iVIZIA Lubricant Eye Gel is offered in preservative-free sterile, single-use vials that are convenient and easy to use for severe dry eye or nighttime use.
iVIZIA We See a Better Way: for healthy, comfortable eyelids

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9.0

Save 15%

Systane

Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)

15% OffFree Shipping

Main Highlights

#1 Dr Recommended Brand of Artificial Tears*
Thicker eye drop formulation that creates a protective shield over your eyes.
Convenience of a drop with a protection of a gel.
For the temporary relief of burning and irritation due to dryness of the eye
NOTE: PRODUCT PACKAGING MAY VARY

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8.8

Save 11%

Refresh

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

11% OffFree Shipping

Main Highlights

Original strength gel formula
Relieves dry, burning, irritated eyes
Alleviates discomfort
Keeps eyes feeling better longer
Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

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8.6

Save 8%

TheraTears

TheraTears Liquid Gel Nighttime Lubricating Eye Drops for Dry Eyes, Single-Use Vials, 30 Count

8% OffFree Shipping

Main Highlights

IMMEDIATE DRY EYE RELIEF: TheraTears Lubricating Liquid Gel Eye Drops provide immediate, long-lasting relief of dry eye symptoms
HYDRATING EYE DROPS: TheraTears Nighttime dry eye drops have 4X the lubrication* for a subtly thicker, extra hydrating experience for tired, dry eyes while you sleep; *vs. TheraTears Original
PRESERVATIVE FREE EYE DROPS: These eye drops for dry eyes are formulated with the 5 vital electrolytes found in natural tears and are individually sealed for preservative free eye drops in a single-use vial
CREATED BY AN OPHTHALMOLOGIST: TheraTears was created by an ophthalmologist after 18 years of research for a one-of-a-kind eye drop
DOCTOR RECOMMENDED: Doctor recommended and created to bring balance and hydration to dry eyes

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8.3

Save 19%

Genteal

Genteal Tears Gel Drops, 8 ml

19% OffFree Shipping

Main Highlights

Product Type:Medication
Item Package Dimension:1.75 " L X1.25 " W X3.88 " H X
Item Package Quantity:1
Country Of Origin: United States

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8.1

Save 15%

TheraTears

TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

15% OffFree Shipping

Main Highlights

IMMEDIATE DRY EYE RELIEF: TheraTears Lubricating Eye Drops provide immediate, long-lasting relief of dry eye symptoms
INSTANT HYDRATING EYE DROPS: TheraTears dry eye drops provide instant, fast silky hydration for tired, dry eyes
ELECTROLYTE FORMULA: These eye drops for dry eyes are formulated with the 5 vital electrolytes found in natural tears
PRESERVATIVE FREE EYE DROPS: These eye drops come in a single-use vial and are preservative free
CREATED BY AN OPHTHALMOLOGIST: TheraTears was created by an ophthalmologist after 18 years of research for a one-of-a-kind eye drop

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Best Value

8.1

Save 54%

Refresh

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

54% Off

Main Highlights

FAST-ACTING: Rapid relief to comfort dry, irritated eyes
LASTING RELIEF: Soothes and prevents further irritation
TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
ON-THE-GO VIALS: 30 sterile single-use vials per carton that are easy and safe to use as often as needed
TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan

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Our Best Overall Choice

Best Choice

9.7

TheraTears

TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Vials, 30 Count (Pack of 2)

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

IMMEDIATE DRY EYE RELIEF: TheraTears Lubricating Liquid Gel Eye Drops provide immediate, long-lasting relief of dry eye symptoms
HYDRATING EYE DROPS: TheraTears Nighttime dry eye drops have 4X the lubrication* for a subtly thicker, extra hydrating experience for tired, dry eyes while you sleep; *vs. TheraTears Original
PRESERVATIVE FREE EYE DROPS: These eye drops for dry eyes are formulated with the 5 vital electrolytes found in natural tears and are individually sealed for preservative free eye drops in a single-use vial
CREATED BY AN OPHTHALMOLOGIST: TheraTears was created by an ophthalmologist after 18 years of research for a one-of-a-kind eye drop
DOCTOR RECOMMENDED: Doctor recommended and created to bring balance and hydration to dry eyes

Show Price