10 Best Eye Drops Use With Contacts of 2025

Tested and Reviewed: Top 10 Eye Drops Use With Contacts deals with expert ratings from 8.1 to a perfect 10

August 2025 Edition

Editor's Choice

9.7

Biotrue

Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Naturally Inspired, 0.33 FL OZ (10 mL) 2 Count (Pack of 1)

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Editor's bottom line:

“This eye drops use with contacts is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.
EYE DROPS and MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, and ointments to help your eyes feel moisturized and protected.

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Picked by 178 people today

9.5

Refresh

REFRESH Contacts Contact Lens Comfort Moisture Drops 0.40 oz (Pack of 2)

Main Highlights

(pack of 2) 658880

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9.5

Save 6%

Biotrue

Biotrue Hydration Boost Rehydrating Contact Lens Eye Drops from Bausch + Lomb, Hydrating, Preservative Free, Naturally Inspired, 0.33 FL Oz (10 mL)

6% OffFree Shipping

Main Highlights

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost for Contacts are enhanced with HA (Hyaluronan), Antioxidant (Protects HA from free radicals), and Electrolyte.
LASTING MOISTURE: For up to 8 hours of moisture (based on a laboratory study) and to help prevent deposit buildup.
REWETTING DROPS FOR CONTACT LENSES: Biotrue Hydration Boost for Contacts are the first preservative free multi-dose contact lens drops.
BIOTRUE CONTACT LENS DROPS: Not only are Biotrue Hydration Boost for Contacts free of preservatives but they are also pH balanced for comfort.
EYE DROPS and MORE: Bausch plus Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, and ointments to help your contacts and eyes feel moisturized and protected.

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Best Value

9.2

Save 22%

Refresh

Refresh RELIEVA FOR CONTACTS Lubricant Eye Drops For Use with Contact Lenses, 0.27 fl oz (8 mL)

22% OffFree Shipping

Main Highlights

Innovative formula specially designed for contact lens wearers
Relieves mild to moderate symptoms of eye dryness, irritation, and discomfort associated with contact lens wear
Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
You may keep your contacts in upon application
May also be used to lubricate and rewet soft and rigid gas permeable (RGP) contact lenses and to cushion lenses prior to application

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9.0

Save 15%

TheraTears

TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

15% OffFree Shipping

Main Highlights

TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
TheraTears corrects the salt imbalance that can cause dry eye symptoms
Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness
Doctor recommended and created; TheraTears was created by an ophthalmologist after 18 years of research
Contains 1 box of TheraTears Dry Eye Therapy Lubricant Drops, Preservative Free, 30 vials
FSA- and HSA-eligible product in the U.S.

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8.8

Systane

Systane Contacts Soothing Drops-0.405 oz, 12mL

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Main Highlights

Systane Contacts Lubricant Eye Drops moisturizes and soothes dry eyes caused by wearing soft and RGP lenses
Alcon

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8.6

Save 7%

Refresh

Refresh Plus Lubricant Eye Drops, Preservative Free, Single Use Containers, 30 Count

7% OffFree Shipping

Main Highlights

Original strength, preservative-free formula
Relieves mild symptoms of eye dryness
Instantly moisturizes and lubricates
Designed to act like your own natural tears
Great for sensitive eyes
On-the-go single use vials
Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

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8.3

Clear Eyes

Clear Eyes Eye Drops, Contact Lens Multi-Action Relief,2 Count

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Main Highlights

Clear Eyes Contact lens multi-action relief eye drops. Use while wearing daily and extended-wear soft contact lenses
These soothing eye drops feature a sterile, buffered solution that refreshes and lubricates eyes for up to 12 hours
Moistens lenses and helps remove particulate matter that can cause irritation and discomfort
Pack of 2

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8.1

Save 18%

BLINK

Blink Contacts Lubricating Eye Drops for Soft & RGP Contact Lenses, Lubricant Eye Drops with Hyaluronate for Hydration, Moisturizing & Comforting Daily Eye Care, 0.34 fl oz

18% OffFree Shipping

Main Highlights

Relief with Every Blink: Blink Contacts Lubricating Eye Drops moisturize dry contact lenses to provide long-lasting comfort. These drops work with the eye's natural tears to help keep your contact lenses feeling fresh and comfortable all day
Hydration Boost with Hyaluronate: Our moisturizing eye drops instantly moisturize dry lenses. Our unique hyaluronate formulate works as a hydration booster to help contacts stay refreshed and comfortable through end of day
Comfort till End of Day: Blink Contacts Lubricating Eye Drops are formulated with beneficial electrolytes similar to those found in natural tears. Enjoy the freedom to wear your soft or RGP lenses while experiencing long-lasting comfort
Moisturizes Dry Lenses: The Blink Contacts Lubricating Eye Drops rewet and moisturize lenses before insertion and during wear, moisturizing and refreshing lenses. They reduce the feeling of contact lens dryness to help maintain comfort to the end of the day
Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated.

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8.1

Save 16%

Clear Eyes

Clear Eyes Contact Lens Relief Eye Drops, 0.5 Fl Oz

16% OffFree Shipping

Main Highlights

Clear Eyes Contact Lens Multi-Action Relief Eye Drops provide relief for dry and irritated eyes
Lubricating eye drops for contact lens wearers
Relieves dry eyes and soothes and moisturizes.Store at room temperature
Rewets lenses and removes particles from lenses
Provides up to 12 hours of soothing comfort
From the #1-selling eye drops brand* *Based on units sold per IRI MULO+C, calendar years 2014-2019 and L52 weeks ending 7/12/20
Contains 1 bottle of Clear Eyes Contact Lens Multi-Action Relief Eye Drops, 0.5 fl oz
FSA- and HSA-eligible product in the U.S.

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Our Best Overall Choice

Best Choice

9.7

Biotrue

Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Naturally Inspired, 0.33 FL OZ (10 mL) 2 Count (Pack of 1)

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.
EYE DROPS and MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, and ointments to help your eyes feel moisturized and protected.

Show Price

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Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

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Optase Allegro Eye Drops for Dry Eyes - Lubricating Drops for Dry, Red, and Itchy Eyes - Relief from Seasonal Irritants - Contact Lens Safe - .33 oz, 300 Drops

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