10 Best Enzymatic Odor Eliminator of 2025

Tested and Reviewed: Top 10 Enzymatic Odor Eliminator deals with expert ratings from 8.1 to a perfect 10

April 2026 Edition

Editor's Choice

9.7

Rocco & Roxie Supply Co.

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

Editor's bottom line:

“This enzymatic odor eliminator is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Certified Gentle & Safe Pet Carpet Cleaner Solution: Chlorine free, color safe, no hazardous propellants or residue; safe to use around pets and children; certified safe for all carpets with a Seal of Approval by the Carpet and Rug Institute (CRI)
Pet Enzyme Carpet Cleaner for Stains, Odors, Residue: If it's gross, it's gone; the stain and the stink; from stinky yellow pet urine, feces to vomit or other organic spills, Rocco & Roxie professional strength stain & odor eliminator tackles it all
Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areasanywhere stains happen enzyme cleaner for dog urine
Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areasanywhere stains happen enzyme cleaner for dog urine
Buy With Confidence: You want the best for your best friend; we do, too; if you are not satisfied with the performance of this Rocco & Roxie stain & odor eliminator, contact us; we are determined to make it rightx

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Picked by 397 people today

9.5

Save 15%

Nature's Miracle

Nature’s Miracle Advanced Stain and Odor Eliminator Dog Spray, Fresh Scent, Severe Mess Enzymatic Formula for Tough Pet Messes, 32 Ounces,red

15% Off

Main Highlights

FOR SEVERE DOG MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from dog urine, diarrhea, vomit and other bio-based accidents.
LIGHT FRESH SCENT: Dog odor control formula gets your home smelling clean again.
ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
DISCOURAGES RESOILING: Removes the odor from even the toughest dog messes.
TRUSTED BRAND: From the maker of Natures Miracle products, the pet stain and odor removing brand you trust because it works!

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Best Value

9.5

Save 17%

Nature's Miracle

Nature’s Miracle Stain and Odor Remover Dog, 32 Ounces, Everyday Mess Enzymatic Odor Control Formula

17% Off

Main Highlights

SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
TRUSTED BRAND: From the maker of Natures Miracle products, the pet stain and odor removing brand you trust because it works!
SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.

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9.2

Save 10%

POOPH

POOPH Pet Odor Eliminator, 32oz - Eliminates Odors at The Molecular Level, Dogs, Cats, Freshener, Eliminator, Urine, Poop, Pee, Deodorizer, Natures, Puppy, Fresh, Clean, Furniture, Potty

10% Off

Main Highlights

POOPH SAFELY eliminates the toughest odors WITHOUT fragrances or harmful ingredients. Its smarter to ELIMINATE odors instead of COVERING THEM UP with fragrances Fragrances can be particularly irritating for dogs and cats who have 10,000X greater sense of smell than people! Even fragrances that smell good in household products have been characterized as potentially dangerous indoor air pollutants associated with a wide range of unexpected health consequencesso choose the products that get into your home wisely!
Proprietary technology eliminates odors at the source, leaving NO chemical residuals or fragrances behind just clean, fresh air.
POOPH SAFELY eliminates stink from carpets, rugs, upholstery, drapes or hard surfaces and leaves no NO chemical residuals or fragrances behind just clean, fresh air.
Ideal for urine, feces, vomit, sour, spoiled and nasty food odors, garbage cans, stinky upholstery and more.
POOPH is eco-conscious and SAFE for people, pets, and plants because it contains no fragrances harmful ingredients.
POOPH, Inc. is an official sponsor of Best Friends Animal Society, a national organization committed to saving homeless pets by connecting them with loving homes. POOPH, Inc., a leading manufacturer and distributor of pet odor eliminating products, is committed to supporting the organizations Bring Happy Home fundraising campaign, slated for National Pet Month in May 2025, as well as throughout the rest of the year.

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9.0

Bioda

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

Main Highlights

THE POWER OF ONE: This versatile product is the only probiotic cleaner you need, providing powerful cleaning performance in a wide variety of applications. Multipurpose use: Maintain clean drain lines and septic tanks to prevent clogs and potential buildup. Clean and deodorize trash bins, stains and odors on floors, carpets, bathroom surfaces, kitchen surfaces, and more.
ACTIVE UP TO 21 DAYS: Our specialized probiotics continue to clean soils in cracks, grout and tough to reach places. Simply spray & let the probiotics do the dirty work!
NATURALLY, SUPERIOR RESULTS: A special blend of enzyme-producing probiotics break down complex proteins, fats, oils, greases, and other organic waste. The enzymes digest the soils until they have been eliminated, providing a long-lasting, continuous clean without leaving a residue or harmful by-products behind.
ELIMINATE ODOR: Provide total odor control by eliminating the actual source of even the most pungent organic malodors naturally, including rotting food, urine, feces, vomit, and trash. Plus, the fresh lemon and sage fragrance leaves behind a light, pleasant scent that rejuvenates the air of any environment.
MADE IN THE USA - 1 Gallon Bottle

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8.8

Odorcide

Odorcide K.O.E Kennel Odor Eliminator Concentrate – For Cages, Runs & More – For Home & Kennel w/Safe, Non-Enzymatic Formula (Fresh Scent, 16 oz)

Main Highlights

Use What the Pros Use: Thornell is the top provider of pet smell odor eliminator products to the veterinary industry in North America. This powerful K.O.E. pet odor exterminator with a new fresh scent is designed to remove offensive odors from cages, runs, kennels, floors, tables, walls, and other large areas.
Tough on Odors: Use this pet odor remover to permanently and immediately remove odors in the first application, saving you time and money. This odor remover for house, clinics, groomers, and kennels penetrates to the source of the odor where other odor neutralizer sprays and concentrates only treat surface problems.
Not an Enzyme, not a Mask: Our dog and cat odor eliminator features a unique non-enzymatic formula that works regardless of what application you have used before. K.O.E. cat and dog odor remover concentrate works where other odor enzyme cleaner products havent and cannot.
Easy to Use: Dilute KOE kennel odor eliminator concentrate with the recommended amount of water or cleaning solution. To reach the odor source, saturate the soiled area. The same dilution may be applied with a pump-up sprayer. Let air dry. If the odor persists after the concentrated deodorizer odor eliminator has dried, then reapply.
Safe for Small Pets & Children: No need to fear, pets and children can safely be around areas treated with K.O.E. dog and cat pee odor eliminator immediately after use. Our kennel and home odor eliminator products are non-harmful, non-allergenic, biodegradable, and safe for use on any surface.

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8.6

Zero Odor

Zero Odor Pro - Commercial Strength Eliminator Odor Neutralizer, Room Deodorizer Odor Eliminator Musty Smell - Strongest Odor Eliminator Trigger Spray, (32-ounce)

Main Highlights

Safe and Gentle Formula: Made in the USA, non-toxic, non-allergenic, and biodegradable, making it suitable for use around children and pets, ensuring a clean and safe home.
Eliminate Tough Commercial Odors - Zero Odor PRO Effectively Removes the Most Challenging Odors in Commercial Environments
Temporary Tracer Scent : Zero Pet Odor Eliminator effectively eliminates strong odors, including urine.This pet odor eliminator for home features a "tracer scent" to identify treated areas, which quickly dissipates, leaving no trace.
Industrial Strength : Commercial Air Freshener and Smoke Eliminator Spray, Smoke Deodorizer Odor Eliminator for Home, Cigarette Smell Eliminator for House and Gasoline Odor Remover Perfect for Eliminating Smoke Smell and Damage Cleaning Products
Spray in the air and on surfaces in any room to permanently eliminate odor and prevent Odor Build up

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8.3

Zeiff

Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce - Fragrance Free

Main Highlights

Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most effective cleaning products to get the job done. Whether youre a pro or just expect pro-grade results, Zeiff delivers Pro Grade Clean
Powerful Cleaning Performance - Our proprietary formulation breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease and grime without leaving any visible residue. Don't just expect clean, expect Zeiff Clean! You'll know it when you see it, clean you didn't even know exists
Multi-Purpose Enzyme Cleaner - The special blend of bacterial enzymes, detergent and deodorant, prevents clogging in drains, grease traps, septic tanks, drain lines and downpipes, and cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and much more. Ideal for Professional and Home use
Deodorizer & Odor Eliminator - Highly concentrated bacterial digestant for grease, stains, oils, & organic waste. Effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage and grease, leaves long-lasting freshness
Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral, paraben-free, pet safe, cruelty-free. Proudly made in the USA

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8.1

Odorcide

Odorcide K.O.E. Apricot Odor Eliminator 16 oz for Strong Odor for Cages, Runs & More – Home & Kennel w/Safe, Non-Enzymatic Formula

Main Highlights

Use What The Pros Use: Thornell is a top provider of pet smell odor eliminator products to the veterinary industry in North America. This powerful K.O.E. pet odor exterminator is designed to remove offensive odors from cages, runs, kennels, floors, tables, walls, and other large areas.
Tough on Odors: Use this pet odor remover to permanently and immediately remove odors in the first application, saving you time and money. This odor remover for house, clinics, groomers, and kennels penetrates to the source of the odor where other odor neutralizer sprays and concentrates only treat surface problems.
Not an Enzyme, Not a Mask: Our dog and cat odor eliminator features a unique non-enzymatic formula that works regardless of what application you have used before. K.O.E. cat and dog odor remover concentrate works where other odor enzyme cleaner products havent and wont.
Easy to Use: Dilute KOE kennel odor eliminator concentrate with the recommended amount of water or cleaning solution. To reach the odor source, saturate the soiled area. The same dilution may be applied with a pump-up sprayer. Reapply if the odor persists after the concentrated deodorizer odor eliminator has dried.
Safe for Small Pets & Children: No need to fear, pets and children can safely be around areas treated with K.O.E. dog and cat pee odor eliminator immediately after use. Our kennel and home odor eliminator products are non-toxic, non-allergenic, biodegradable, and safe for use on any surface.

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8.1

Black Diamond Stoneworks

Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon)

Main Highlights

Powerful Enzymatic Action Breaks down stains and odors at the source - from pet accidents to everyday messes. Keep your home fresh, clean, and worry-free.
Eliminates Odors in Seconds Neutralizes dog, cat, and human urine smells from carpets, floors, drains, and more. Because lifes too short for lingering odors.
Multi-Surface Safe & Family-Friendly Gentle on carpets, hardwood, tile, upholstery, and more tough on messes, safe for pets and kids. Clean with confidence.
Perfect for Pet Accidents & Beyond Tackles stains, urine, vomit, and more from litter boxes to kennels to everyday spills. Freshness where you need it most.
Commercial Strength. Home Safe. Trusted by homeowners, vets, and cleaners alike biodegradable, non-toxic, and ready for the toughest jobs, big or small.

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Our Best Overall Choice

Best Choice

9.7

Rocco & Roxie Supply Co.

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Certified Gentle & Safe Pet Carpet Cleaner Solution: Chlorine free, color safe, no hazardous propellants or residue; safe to use around pets and children; certified safe for all carpets with a Seal of Approval by the Carpet and Rug Institute (CRI)
Pet Enzyme Carpet Cleaner for Stains, Odors, Residue: If it's gross, it's gone; the stain and the stink; from stinky yellow pet urine, feces to vomit or other organic spills, Rocco & Roxie professional strength stain & odor eliminator tackles it all
Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areasanywhere stains happen enzyme cleaner for dog urine
Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areasanywhere stains happen enzyme cleaner for dog urine
Buy With Confidence: You want the best for your best friend; we do, too; if you are not satisfied with the performance of this Rocco & Roxie stain & odor eliminator, contact us; we are determined to make it rightx

Show Price

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