10 Best Cvs Hydrocortisone Cream of 2025

Tested and Reviewed: Top 10 Cvs Hydrocortisone Cream deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Cortizone 10

Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

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Editor's bottom line:

“This cvs hydrocortisone cream is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

INCLUDES: One (1) 2 oz. tube of Cortizone-10 Maximum Strength* Intensive Healing Itch Relief Cream (*Among topical anti-itch OTCs)
RELIEVES ITCH: Cortizone-10 helps relieve itch associated with minor skin irritations, inflammation, and rashes due to eczema, psoriasis, insect bites, seborrheic dermatitis, poison ivy, oak, sumac, and more
MOISTURIZES & RESTORES: Includes 10 moisturizers, plus vitamins A, C, and E to nourish skin and help restore skin's moisture barrier
ACTIVE INGREDIENT: Formulated with 1% hydrocortisone for maximum-strength itch relief without a prescription
TRAVEL ESSENTIALS: The perfect addition to first aid kits, camping essentials and travel bags for anytime you need on-the-go relief
FAST ACTING: Relieves itch in five minutes with 24-hour moisture that's gentle on skin, fragrance free, and dye free
DOCTOR RECOMMENDED: Cortizone-10 is the No. 1 doctor-recommended OTC anti-itch brand* and is suitable for adults and children ages 2+ (*2024 IQVIA Study)

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Picked by 397 people today

9.5

Amazon Basic Care

Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, 1 ounce (Pack of 1)

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Main Highlights

ACTIVE INGREDIENT: The active ingredient in this anti-itch cream is hydrocortisone 1 percent; compare to the active ingredient in Cortizone 10 Intensive Healing Formula
MAXIMUM STRENGTH RELIEF: Hydrocortisone is the number one doctor recommended anti-Itch active Ingredient (of U.S. physicians surveyed by an independent market research firm)
POWERFUL MEDICINE, FAST RELIEF: Great for relieving itching associated with skin irritation, rashes, inflammation, redness, insect bites, eczema, psoriasis and poison ivy, oak and sumac
LASTS UP TO 10 HOURS when used as directed; ultra creamy, maximum strength hydrocortisone formula helps heal problem skin; safe for sensitive skin; for adults and children age 2 years of age and older
INTENSIVE HEALING FORMULA calms, nourishes and hydrates; clinically proven to moisturize for up to 24 hours; features antioxidants, chamomile and Vitamins A, C and E

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9.5

MED PRIDE

MED Pride Hydro Cortisone (Hydrocortisone) Cream 1% OTC Bulk Pack of 4 X 1 Oz Anti-Itch Ointment for Rash, Eczema, Bug Bites

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Main Highlights

SOOTHING POWER: Experience the soothing power of hydrocortisone 1% cream, a versatile topical ointment designed to alleviate a variety of common skin conditions. With hydrocortisone cream 1%, you can provide immediate relief from itchiness, redness, and swelling caused by conditions such as rashes, eczema, bug bites, and even external hemorrhoids.
POTENT ANTI-ITCH: Unleash the power of 1% hydrocortisone cream, a potent anti-itch compound that forms the core of our cream's formula. No prescription needed with our hydrocortisone ointment, you have the most powerful over-the-counter anti-itch ointment at your disposal.
DISCOMFORT RELIEF: Say goodbye to discomfort with our mosquito bite itch relief, simply apply the cream directly to the affected skin area and let it absorb. Whether it's a chigger bite or an irritating rash, our treatment provides fast, soothing relief, making it a reliable solution for all your skin-related concerns.
VERSATILE APPLICATIONS: Trust in the versatility of our dermatitis cream, suitable for a wide range of applications. From rashes to mosquito bites, our cream provides immediate itch relief, making it a versatile addition to your first aid kit.
POISON IVY TREATMENT: Rely on MED PRIDE Hydrocortisone Cream for your poison ivy treatment, a product designed with your health and comfort in mind. Wondering what stops itching fast? With its potent formula and versatile applications, our cream is a reliable solution for all your skin-related concerns.

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9.2

MED PRIDE

MED Pride Hydrocortisone Cream 1%, 1 oz – Maximum Strength Anti-Itch & Anti-Inflammatory Treatment for Eczema, Dermatitis, Rashes, Poison Ivy, Redness & Minor Skin Irritation

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Main Highlights

MAXIMUM-STRENGTH 1% HYDROCORTISONE RELIEF Helps reduce itching, redness, swelling and irritation caused by eczema, dermatitis, allergic reactions, poison ivy/oak, rashes, dry skin patches, and minor skin irritations.
TARGETED RELIEF FOR MULTIPLE SKIN CONDITIONS Suitable for treating eczema hot spots, heat rash, contact dermatitis, allergic rashes, psoriasis symptoms, and irritated skin due to sweat or friction.

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9.0

Amazon Basic Care

Amazon Basic Care Hydrocortisone 1% Anti-Itch Cream, White, 2 Ounce (Pack of 1)

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Main Highlights

ACTIVE INGREDIENT: Amazon Basic Care Maximum Strength Hydrocortisone 1 Percent Anti-Itch Cream contains vitamins A, D and E plus aloe, with the active ingredient hydrocortisone 1 percent; compare to Cortizone 10 Plus Maximum Strength active ingredient
HYDROCORTISONE CREAM: Amazon Basic Care Maximum Strength Hydrocortisone 1 Percent Anti-Itch Cream contains the number one doctor recommended anti-itch active ingredient (of U.S. physicians surveyed by an independent market research firm)
PLUS 10 SOOTHING MOISTURIZERS: Our hydrocortisone cream is enriched with vitamins A, D and E plus aloe to soothe and moisturize while relieving itch fast
FOR FAST, POWERFUL RELIEF of itches and rashes due to: eczema; psoriasis; seborrheic dermatitis; poison ivy, oak, and sumac; insect bites; external genital and anal itching; soaps; detergents; cosmetics; jewelry
KEEP ANTI-ITCH CREAM in your first aid kit and medicine cabinet to make sure you are able to fight itch fast with ultra-moisturizing relief for skin redness, irritation, rashes, inflammation, eczema and psoriasis

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8.8

CeraVe

CeraVe 1% Hydrocortisone Anti-Itch Cream, Fragrance-Free Relief for Eczema-Prone & Dry Skin, 1 Ounce

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Main Highlights

[ MAXIMUM STRENGTH ] 1% Hydrocortisone, the maximum strength Hydrocortisone Cream without a prescription, to provide temporary itch relief from extra dry skin, eczema-prone skin, as well as relief for minor skin irritations and rashes.
[ HYDRATING ITCH RELIEF CREAM ] With Hyaluronic Acid to help retain skins natural moisture and Niacinamide to help calm skin.
[ GENTLE ON SKIN ] Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free, non-irritating, and non-comedogenic.
[ 3 ESSENTIAL CERAMIDES ] Ceramides make up 50% of the lipids in the skin barrier. CeraVe products are formulated with three essential ceramides (1; 3; 6-II) to help restore & maintain the skins natural barrier.
[ DEVELOPED WITH DERMATOLOGISTS ] CeraVe Skincare is developed with dermatologists and has products suitable for dry skin, sensitive skin, oily skin, acne-prone, and more. This product is non-sealed. FSA Eligible & HSA Eligible

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8.6

KIRKLAND

Kirkland Signature Maximum Strength Hydrocortisone Cream 1% with Aloe, 2-ounce (pack of 4)

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Main Highlights

Anti-itch cream with aloe
Soothes itching and rashes
Eases eczema irritation
Eases Psoriasis irritation

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8.3

Dr. Dan's

Dr. Dan's Hydrocortisone Hand and Body Lotion - Anti Itch Lotion for Men and Women - 1 Pack

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Main Highlights

ITCH RELIEF LOTION: This premium lotion for itchy skin is formulated by a leading Dermatologist. It helps by restoring the skin moisture and is perfect for dry chapped hands and skin. An ideal and quick solution to your itching skin problem!
REPAIR & NOURISH SKIN: This treatment contains 1% hydrocortisone which interrupts the inflammatory cycle, stops the pain and allows the natural healing process to begin.
VARIOUS SKIN PROBLEM TREATMENT: Using our medicated hand and body lotions will not just give itchy skin relief but also great defense for many skin issues like eczema, psoriasis, and dermatitis as well.
EXTRA STRENGTH ANTI ITCH LOTION: Applying a thin amount of Dr. Dan's Hydrocortisone Hand and Body Lotion to the affected area of your skin will give itch skin relief fast.
FOR SENSITIVE SKIN: Our itchy skin lotion is safe for most skin types. Men and women with sensitive skin can use this product without any worry. It is proven and tested!

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8.1

Thera Care

Thera|Care Hydrocortisone Cream | Maximum Strength OTC | Itch Irritation and Rash Relief | 1 oz

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Main Highlights

LONG-LASTING RELIEF Temporarily helps relieve itch associated with minor skin irritation and rashes due to insect bites; psoriasis; eczema and poison ivy, oak, and sumac.
FAST ACTING HYDROCORTISONE CREAM Works by calming down your body's immune response to reduce pain, itching and swelling (inflammation).
SUPPORT AND INSTRUCTION Follow the detailed use instructions, as well as the warnings and cautions, before use. Use only as directed, instructions are easy to follow and use
Compare to Cortizone 10 Maximum Strength Anti-Itch Cream active ingredients 1 oz. (28.3 g) tube
Safety warning: For external use only Do not use: in genital area if you have a vaginal discharge, for the treatment of diaper rash, with any other hydrocortisone product unless you have asked a doctor
Always read detailed instructions before use

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8.1

AVEDANA

AVEDANA Hydrocortisone Cream – 1 Ounce Eczema Cream with Aloe Vera – Premium Anti Itch Cream Extra Strength – Ideal for Rashes, Itchiness, Insect Bites, Dermatitis, Detergents, Jewelry

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Main Highlights

A Must In Your Home: Whether youre constantly dealing with itchiness and rashes or other skin conditions, or you simply want to make sure your medical supply kit is always up to date with essential items, the Avedana eczema lotion is the perfect choice!
Maximum Strength Formula: This cortisone cream is made with premium quality, powerful active ingredients, with maximum strength 1% USP hydrocortisone and aloe, being gentle and safe for your delicate skin.
Soothing Aloe Vera: Unlike similar products on the market, this anti itch cream contains an innovative formula with aloe vera which has superior calming and soothing effects on the derma, keeping it hydrated and protected for longer.
Wide Applications: This hydrocortisone cream 1 percent can be used for a wide variety of conditions, including insect bites, eczema, poison ivy or oak, seborrheic dermatitis, psoriasis, rashes and irritations caused by soap, jewelry, detergents or cosmetics.
Easy to Apply: The Avedana rash cream has a lightweight, rapidly absorbed formula which penetrates instantly into the skin and leaves no greasy residue, making application a breeze.

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Our Best Overall Choice

Best Choice

9.7

Cortizone 10

Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

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Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

INCLUDES: One (1) 2 oz. tube of Cortizone-10 Maximum Strength* Intensive Healing Itch Relief Cream (*Among topical anti-itch OTCs)
RELIEVES ITCH: Cortizone-10 helps relieve itch associated with minor skin irritations, inflammation, and rashes due to eczema, psoriasis, insect bites, seborrheic dermatitis, poison ivy, oak, sumac, and more
MOISTURIZES & RESTORES: Includes 10 moisturizers, plus vitamins A, C, and E to nourish skin and help restore skin's moisture barrier
ACTIVE INGREDIENT: Formulated with 1% hydrocortisone for maximum-strength itch relief without a prescription
TRAVEL ESSENTIALS: The perfect addition to first aid kits, camping essentials and travel bags for anytime you need on-the-go relief
FAST ACTING: Relieves itch in five minutes with 24-hour moisture that's gentle on skin, fragrance free, and dye free
DOCTOR RECOMMENDED: Cortizone-10 is the No. 1 doctor-recommended OTC anti-itch brand* and is suitable for adults and children ages 2+ (*2024 IQVIA Study)

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