10 Best Cockroach Killer Powder of 2025

Tested and Reviewed: Top 10 Cockroach Killer Powder deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Ortho

Ortho Orthene Fire Ant Killer1 – Fire Ant Mound Treatment, Kills Queens, No Watering Needed, Treats up to 162 Mounds, 12 oz (2-Pack)

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Editor's bottom line:

“This cockroach killer powder is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Kills Fire Ants & the Queen: Ortho Orthene Fire Ant Killer1 targets the entire colony to get rid of ants at the source
Fast-Acting Fire Ant Treatment: Fire ant granules begin killing in just 60 minutes so you can get back to enjoying your yard fast
Outdoor Lawn and Yard Use: Kill fire ants on your lawn and around ornamental plants, including flowers, trees, and shrubs
Treats Up to 162 Fire Ant Mounds: Simply sprinkle the product over each mound using amount specified on the product label, no watering-in needed
Ortho 2-Step System: This pack includes two 12 oz. bottles of Ortho Orthene Fire Ant Killer1; For best results, use with Ortho Fire Ant Killer Broadcast Granules, sold separately

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Picked by 397 people today

9.5

Ortho

Ortho Orthene Fire Ant Killer1, Kills The Queen, Destroys up to 189 Mounds, Begins Working in 60 Minutes, 14 oz.

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Main Highlights

Ortho Orthene Fire Ant Killer1 kills the queen, destroys the mound, and treats up to 189 mounds
This fire ant killer begins killing in just 60 minutes so you can get back to enjoying your yard fast
Kill fire ants outdoors on your lawn and around ornamental plants, including flowers, trees and shrubs
To treat fire ant mounds, simply sprinkle the product over each mound using amount specified on the product label
Use as part of the Ortho 2-Step System with Ortho Fire Ant Killer Broadcast Granules (sold separately), which prevents new fire ant mounds from forming for up to 6 months

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9.5

HARRIS

HARRIS Boric Acid Roach and Silverfish Killer Powder w/Lure for Insects (16oz)

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Main Highlights

Long Lasting - Continues to kill roaches, palmetto bugs, water bugs and silverfish for weeks after application as long as it's kept dry
Fast Acting - Insects coming into contact with the powder will die within 72 hours after initial contact
Easy Application - The puffer bottle makes application quick and simple for difficult to reach areas
Contains Irresistible Lure - Harris food grade lure attracts roaches from their hiding places
EPA Registered - Made in the USA & Registered with the Environmental Protection Agency (No. 3-10) for use in homes with people and pets

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9.2

Ortho

Ortho Orthene Ant and Roach Killer, Provides Long-Lasting Insect Control, for Indoor and Outdoor Use, 1 lb.

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Main Highlights

Ortho Orthene Ant & Roach Killer is a ready-to-use insect killer dust that works to kill listed insects for up to 8 months
This odorless insect killer controls ants, roaches, fleas, ticks, spiders, scorpions, stink bugs and other listed pests
Use this pest control product indoors to treat cracks, crevices and other hiding and runway areas; apply outdoors as a perimeter treatment or to ornamentals, flowers and listed vegetable plants
Our roach and ant killer is for residential use in and around homes, ornamentals, shrubs, and vegetable gardens
Application rates for Ortho Orthene Ant & Roach Killer vary; please review all label directions before use

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9.0

HARRIS

Harris Boric Acid Roach and Silverfish Killer Powder w/Lure, Powder Duster Included in The Bag (32oz)

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Main Highlights

Long Lasting - Continues to kill roaches, palmetto bugs, water bugs and silverfish for weeks after application as long as it's kept dry
Fast Acting - Insects coming into contact with the powder will die within 72 hours after initial contact
Easy Application - The powder duster with extended straw makes application quick and simple for difficult to reach areas
Contains Irresistible Lure - Harris food grade lure attracts roaches from their hiding places
EPA Registered - Made in the USA & Registered with the Environmental Protection Agency (No. 3-10) for use in homes with people and pets

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8.8

JT Eaton

Crawling Insect Killer, Powder

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Main Highlights

PROVEN PEST CONTROL: Eliminates roaches, ants, and other labeled insects with a simple and effective boric acid formula
LOW HAZARD FORMULA: Contains low-risk boric acid powder, making it a safer option for use around the home
USER-FRIENDLY APPLICATION: Comes in an easy-to-use puffer bottle for precise and mess-free application
VERSATILE PROTECTION: Ideal for targeting indoor infestations, ensuring your space remains pest-free
LEGACY OF TRUST: Since 1932, JT Eaton has been a trusted partner for PMPs worldwide, pioneering solutions like the first paraffin bait block and modern glue board. Today, we continue to lead with innovative products for both the pest control and retail industries.

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8.6

HARRIS

Harris Roach Tablets, Boric Acid Roach and Insects Killer with Lure, Alternative to Bait Traps (6oz, 145 Tablets), Yellow

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Main Highlights

Great Value - Minimum of 145 tablets included to treat a minimum of 12 rooms, long lasting when kept dry & extremely cost effective
EPA Registered - Registered with the Environmental Protection Agency (No. 3-1) for use in homes with people & pets
Irresistible to Roaches - Active ingredient 40% boric acid w/ our formulated lure to attract roaches. Does not have an expiration date.
Kills the Entire Colony - Roaches carry boric acid back to their nests to kill the entire infestation
Easy to Conceal - Use in hidden areas - under drawers, appliances and cabinets

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8.3

Atticus

Atticus Tirade 1% Cyfluthrin Dust Insecticide (1.25 lb) - Ready-to-Use Insect Killer - Indoor and Outdoor Control of Ants, Bees, Wasps, Hornets, Cockroaches and Many Other pests

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Main Highlights

POWERFUL BROAD-SPECTRUM CONTROL: Tirade 1% Dust contains cyfluthrin, the same active ingredient as the leading brand, to control flying, crawling, and wood-infesting insect pests.
READY TO USE + EASY TO APPLY: Control insects without the hassle of measuring and mixing. Our convenient dust formulation comes ready to use and is easy to apply in hard-to-reach areas. See product label for complete application directions.
KILL 50+ HOUSEHOLD INSECTS: Wipe out common household insects including bed bugs, ants, wasps, roaches, spiders, and more. Plus, Tirade 1% Dust delivers lasting residual to keep pests in check after application. See product label for complete control list.
ONE PRODUCT FOR INDOOR + OUTDOOR USE: Tirade 1% Dust may be used in residential and commercial settings including kitchens, living areas, and pet kennels. Apply as a barrier treatment outside and crack and crevice treatment inside for lasting insect takedown. Plus, Tirade 1% Dust Insecticide powder may be applied to upholstery for bed bug control and ant mounds for fire ant control. See product label for complete control list and use instructions.
NO STAINS, NO STRONG SCENTS: Tirade 1% Dust is low-odor and non-staining so all youll notice after application is lasting insect control.
NOT AVAILABLE FOR SALE IN ALASKA, CALIFORNIA, HAWAII, PUERTO RICO, OR VERMONT. Always read and follow label instructions. Not all products are registered for use in every state.

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8.1

Ortho

Ortho Orthene Fire Ant Killer

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Main Highlights

Starts to kill in hours
No watering-in required
Reduced odor formula
Built-in seal opener - no tools needed
50% Acephate

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8.1

HARRIS

Harris 8 oz Diatomaceous Earth Crawling Insect Killer — 100% Natural Dust for Ants, Roaches, Bed Bugs, Fleas — Indoor & Outdoor Use

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Main Highlights

POWERFUL CRAWLING INSECT KILLER : Effectively kills a wide range of crawling insects including ants, bed bugs, cockroaches, fleas, earwigs, silverfish, and spiders. A natural solution for indoor and outdoor pest control without harsh chemicals.
100% DIATOMACEOUS EARTH WITH NO ADDITIVES : Made from pure freshwater diatomaceous earth, this powder is non-toxic, pet-friendly (when used as directed), and safe for use around kids and animals. A trusted choice for eco-conscious households.
KILLS INSECTS MECHANICALLY, NOT CHEMICALLY : Works by dehydrating insects on contact through physical abrasion. Insects walk through the powder and the fine particles damage their exoskeleton, leading to rapid dehydration and death.
LONG-LASTING INDOOR & OUTDOOR PROTECTION : Remains effective as long as the powder stays dry. Use in basements, attics, gardens, garages, and entry points to create a barrier against future infestations.
EPA REGISTERED - Registered with the Environmental Protection Agency (No. 3-18)
BUILT-IN PUFFER TIP FOR PRECISE CONTROL The included powder duster features a narrow, easy-to-use puffer tip that allows for targeted application in tight spaces and cracks. Apply just the right amount of diatomaceous earth exactly where insects hideno waste, no mess.
TRUSTED BRAND SINCE 1928: Harris has been providing effective pest control and insect management solutions for nearly a century, trusted by professionals and homeowners alike.

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Our Best Overall Choice

Best Choice

9.7

Ortho

Ortho Orthene Fire Ant Killer1 – Fire Ant Mound Treatment, Kills Queens, No Watering Needed, Treats up to 162 Mounds, 12 oz (2-Pack)

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Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Kills Fire Ants & the Queen: Ortho Orthene Fire Ant Killer1 targets the entire colony to get rid of ants at the source
Fast-Acting Fire Ant Treatment: Fire ant granules begin killing in just 60 minutes so you can get back to enjoying your yard fast
Outdoor Lawn and Yard Use: Kill fire ants on your lawn and around ornamental plants, including flowers, trees, and shrubs
Treats Up to 162 Fire Ant Mounds: Simply sprinkle the product over each mound using amount specified on the product label, no watering-in needed
Ortho 2-Step System: This pack includes two 12 oz. bottles of Ortho Orthene Fire Ant Killer1; For best results, use with Ortho Fire Ant Killer Broadcast Granules, sold separately

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10 Best Cockroach Killer Powder of 2025

Tested and Reviewed: Top 10 Cockroach Killer Powder deals with expert ratings from 8.1 to a perfect 10

Ortho

Ortho Orthene Fire Ant Killer1 – Fire Ant Mound Treatment, Kills Queens, No Watering Needed, Treats up to 162 Mounds, 12 oz (2-Pack)

Editor's bottom line:

Main Highlights

Ortho

Ortho Orthene Fire Ant Killer1, Kills The Queen, Destroys up to 189 Mounds, Begins Working in 60 Minutes, 14 oz.

Main Highlights

HARRIS

HARRIS Boric Acid Roach and Silverfish Killer Powder w/Lure for Insects (16oz)

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Ortho

Ortho Orthene Ant and Roach Killer, Provides Long-Lasting Insect Control, for Indoor and Outdoor Use, 1 lb.

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HARRIS

Harris Boric Acid Roach and Silverfish Killer Powder w/Lure, Powder Duster Included in The Bag (32oz)

Main Highlights

JT Eaton

Crawling Insect Killer, Powder

Main Highlights

HARRIS

Harris Roach Tablets, Boric Acid Roach and Insects Killer with Lure, Alternative to Bait Traps (6oz, 145 Tablets), Yellow

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Atticus

Atticus Tirade 1% Cyfluthrin Dust Insecticide (1.25 lb) - Ready-to-Use Insect Killer - Indoor and Outdoor Control of Ants, Bees, Wasps, Hornets, Cockroaches and Many Other pests

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Ortho

Ortho Orthene Fire Ant Killer

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HARRIS

Harris 8 oz Diatomaceous Earth Crawling Insect Killer — 100% Natural Dust for Ants, Roaches, Bed Bugs, Fleas — Indoor & Outdoor Use

Main Highlights

Our Best Overall Choice

Ortho

Ortho Orthene Fire Ant Killer1 – Fire Ant Mound Treatment, Kills Queens, No Watering Needed, Treats up to 162 Mounds, 12 oz (2-Pack)

Editor's bottom line:

Main Highlights

Deals are Live

Harris 8 oz Diatomaceous Earth Crawling Insect Killer — 100% Natural Dust for Ants, Roaches, Bed Bugs, Fleas — Indoor & Outdoor Use