10 Best Best Mouthwash For Periodontal Disease of 2025

Tested and Reviewed: Top 10 Best Mouthwash For Periodontal Disease deals with expert ratings from 8.1 to a perfect 10

June 2025 Edition

Editor's Choice

9.7

Save 11%

Listerine

Listerine Clinical Solutions Gum Health Antiseptic Mouthwash, Antigingivitis & Antiplaque Oral Rinse Helps Prevent Buildup & Immediately Kills Germs for Healthier Gums, ICY Mint, 1 L

11% OffFree Shipping

Editor's bottom line:

“This best mouthwash for periodontal disease is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

1-liter of Listerine Clinical Solutions Gum Health Antiseptic Mouthwash, an antigingivitis & antiplaque oral rinse in a refreshing icy mint flavor helps prevent buildup & immediately kill germs for healthier gums
The antigingivitis mouthwash treatment immediately kills the germs that cause bleeding gums & inflammation for 3x healthier gums in one week* & helps maintain healthy gums for 12 weeks with continual use* *vs. brushing alone
Proven to maintain oral pH & powered with zinc, this antiplaque oral rinse helps prevent hard to remove buildup on teeth, reduces plaque bacteria below the gumline* & helps to reduce dental plaque while also helping to prevent gingivitis
To use this antiseptic mint mouthwash, adults & children 12 years & older, rinse full strength for 30 seconds with 20 mL in the morning & at night as a part of your twice daily oral care routine
Tested by dentists & hygienists, this ADA-Accepted mouth rinse from Listerine is formulated with eucalyptol, menthol & thymol aids in the prevention of gingivitis & helps control plaque while leaving a refreshing mouth feel
Listerine Clinical Solutions Gum Health Antiseptic Mouthwash, Antigingivitis and Antiplaque Oral Rinse contains alcohol as an inactive ingredient

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Picked by 195 people today

9.5

Save 25%

Listerine

Listerine Gum Therapy Antiplaque & Anti-Gingivitis Mouthwash, Oral Rinse to Help Reverse Signs of Early Gingivitis Like Bleeding Gums, ADA Accepted, Glacier Mint, 1 L

25% OffFree Shipping

Main Highlights

1-liter bottle of Listerine Gum Therapy Antiplaque & Antigingivitis Gum Care Mouthwash cleans below the gum line for a clean mouth and fresh breath with a refreshing glacier mint flavor
This ADA Accepted mouthwash is specially designed to promote gum health by helping reverse the signs of early gum disease such as bleeding, redness, and inflammation for 4-times healthier gums in 3 weeks versus brushing alone when used twice a day
From the #1 dentist recommended brand of over the counter mouthwashes, it also helps remove plaque, one of the leading causes of gum disease. Swish twice a day for 24-hour germ* protection.*Germs that cause plaque, gingivitis, and bad breath
Listerine is 5X more effective than flossing for plaque reduction* (*Sustained plaque reduction above the gum line after a dental cleaning) and is made with the essential oils eucalyptol, menthol, methyl salicylate and thymol as active ingredients
To protect your gums from gingivitis causing germs and promote a whole mouth clean, rinse full strength with 20mL of the anti-gingivitis mouthwash morning and night. Do not swallow

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9.5

Save 14%

Colgate

Colgate Peroxyl Antiseptic Mouthwash and Mouth Sore Rinse, 1.5% Hydrogen Peroxide, Mild Mint - 500ml, 16.9 Fluid Ounces

14% OffFree Shipping

Main Highlights

Mouth rinses cleanses and promotes healing of minor oral wounds
Helps promote healing of: oral sores, irritations, mouth burns
Oxygenating action removes oral debris to facilitate healing
Soothes minor gum inflammation from dental procedures, dentures and orthodontic appliances
Antiseptic mouthwash, alcohol free formula

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9.2

CloSYS

Closys Healthy Gums Mouthwash, Antiplaque and Anti-gingivitis for Gum Health, Non-Burning, Non-Irritating – 32 Fl Oz

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Main Highlights

Kills Germs: Kills germs that cause gingivitis, plaque, and bad breath and leads to healthier gums. Fights plaque build-up.
Helps Reverse Early Signs of Gum Disease: Reverses early signs of gum disease including redness, bleeding, and & inflammation
Freshens Breath: CloSYS Healthy Gums eliminates bad breath and freshens breath with gentle mint flavor
Non-Burning and Alcohol Free: Alcohol Free formula is non-burning and non-irritating. Gentle pH balanced.
Ideal for Sensitive Mouths: CloSYS mouthwash products are dye-free, sulfate free, triclosan-free, alcohol-free, and gluten-free. No harsh chemicals that will irritate or damage the mouth.

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9.0

Save 15%

TheraBreath

TheraBreath Fresh Breath Mouthwash, Icy Mint Flavor, Alcohol-Free, 16 Fl Oz (Pack of 2)

15% OffFree Shipping

Main Highlights

FIGHTS BAD BREATH: TheraBreath Fresh Breath Mouthwash fights bad breath for 24 hours when used every 12 hours after brushing and flossing
DENTIST FORMULATED: Dr. Katz created the TheraBreath formulas in 1993 to help his own daughter with her bad breath
ADA ACCEPTED: Our alcohol-free, non-burning formula is powered by oxygen, and is ADA accepted to help reduce bad breath
RESTORE CONFIDENCE: TheraBreath believes you should define success any way you please. We exist to motivate you to go get it.
IT'S A BETTER MOUTHWASH: Try the fastest growing mouthwash brand in the USA (data on file)

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Best Value

8.8

Save 37%

TheraBreath

TheraBreath Healthy Gums Mouthwash Clean Mint, Antigingivitis, Dentist Formulated, 16 Fl Oz (2-Pack)

37% OffFree Shipping

Main Highlights

PERIODONTAL MOUTHWASH: Helps fight gingivitis, an early form of gum disease and bleeding gums, for 24 hours when used as directed
DENTIST FORMULATED: Dr. Katz created the TheraBreath formulas in 1993 to help his own daughter with her bad breath
ALCOHOL FREE: Non-burning formula made without alcohol that starts working instantly
RESTORE CONFIDENCE: TheraBreath believes you should define success any way you please. We exist to motivate you to go get it!
IT'S A BETTER MOUTHWASH: Try the #1 fastest growing mouthwash brand in the USA (data on file)

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8.6

TheraBreath

TheraBreath Deep Clean Mouthwash, Antigingivitis, Antiseptic, Fresh Mint Flavor, Dentist Formulated, Alcohol Free, 16 fl oz (Pack of 2)

Free Shipping

Main Highlights

16 fl oz TheraBreath Deep Clean Mouthwash; Dentist Formulated; Fresh Mint Flavor; Alcohol Free
Kills Germs Without the Burn; Swishing this mouthwash kills 99.9% of germs that cause bad breath, plaque and gingivitis in laboratory tests.
Deep Clean, Ditch the Alcohol; Take the sting out of killing bad breath germs; this oral care rinse is antiseptic, antigingivitis, antiplaque, antibacterial and free from alcohol, dyes/colors, SLS/sulfates, and parabens
Dentist Formulated; Not tested on animals; certified gluten-free, vegan, Kosher, and Halal
TheraBreath is the #1 Fastest Growing Mouthwash Brand in the USA (1); Try today and swish with confidence

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8.3

TheraBreath

TheraBreath Healthy Gums Periodontist Formulated 24-Hour Oral Rinse, Clean Mint, 3 Ounce (Pack of 6)

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Main Highlights

Periodontal Mouthwash: Regular use of TheraBreath Healthy Gums Orals Rinse may help address bleeding gums, gingivitis, plaque and tartar buildup, and bad breath. Dentist-formulated support for healthy gums
Fresh Mouth, Healthy Gums: Attack bad breath at the source while providing extra support for gum health. Great for gum problems associated with pregnancy, menopause, and other medical conditions
Premium Oral Care: Our solution-oriented line of toothpastes, mouthwashes, breath sprays, tonsil stone kits, and more can help your whole family get the oral hygiene support you need
Professional-Grade Products: TheraBreath's line of dentist-formulated toothpastes, mouthwashes, and other products are designed to help address halitosis, cavity prevention, gum disease, and more
Trusted Quality: Started in 1994 by dentist Dr. Harold Katz, TheraBreath has continued to innovate, delivering an extensive line of the highest-quality oral care products for you and your family. (With added CPC)

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8.1

Parodontax

Parodontax Active Gum Health Mouthwash, Antiplaque and Antigingivitis Mouthwash, Mint, 3x16.9 Fl Oz

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Main Highlights

Three 16.9 fl oz bottle of Parodontax Active Gum Health Mouthwash, Antiplaque and Antigingivitis Mouthwash, Mint
Alcohol-free mouthwash formulated with Cetylpyridinium Chloride (CPC) is designed to target plaque bacteria (1)
Antibacterial mouthwash that kills 99.9 percent of plaque bacteria (1)
Oral rinse forms an antibacterial shield that helps prevent plaque bacteria build-up to help prevent bleeding gums (1)
Features a mint flavor for clean, fresh breath
For best results, use this Parodontax mouthwash daily

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8.1

Parodontax

Parodontax Active Gum Health Breath Freshener Mouthwash, 3 x 16.9 fl oz

Free Shipping

Main Highlights

Three 16.9 fl oz Bottles Parodontax Active Gum Health Breath Freshener Mouthwash for healthy gums and fresh breath
Specially formulated to kill 99.9% of plaque bacteria that could lead to gum problems and bad breath
Forms an antibacterial shield to help prevent bad breath bacteria
Reaches vulnerable hard to reach areas
For best results, use daily as directed
Alcohol-free mouthwash formulated with Cetylpyridinium Chloride (CPC)
Recyclable bottle, recyclable cap

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Our Best Overall Choice

Best Choice

9.7

Listerine

Listerine Clinical Solutions Gum Health Antiseptic Mouthwash, Antigingivitis & Antiplaque Oral Rinse Helps Prevent Buildup & Immediately Kills Germs for Healthier Gums, ICY Mint, 1 L

11% OffFree Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

1-liter of Listerine Clinical Solutions Gum Health Antiseptic Mouthwash, an antigingivitis & antiplaque oral rinse in a refreshing icy mint flavor helps prevent buildup & immediately kill germs for healthier gums
The antigingivitis mouthwash treatment immediately kills the germs that cause bleeding gums & inflammation for 3x healthier gums in one week* & helps maintain healthy gums for 12 weeks with continual use* *vs. brushing alone
Proven to maintain oral pH & powered with zinc, this antiplaque oral rinse helps prevent hard to remove buildup on teeth, reduces plaque bacteria below the gumline* & helps to reduce dental plaque while also helping to prevent gingivitis
To use this antiseptic mint mouthwash, adults & children 12 years & older, rinse full strength for 30 seconds with 20 mL in the morning & at night as a part of your twice daily oral care routine
Tested by dentists & hygienists, this ADA-Accepted mouth rinse from Listerine is formulated with eucalyptol, menthol & thymol aids in the prevention of gingivitis & helps control plaque while leaving a refreshing mouth feel
Listerine Clinical Solutions Gum Health Antiseptic Mouthwash, Antigingivitis and Antiplaque Oral Rinse contains alcohol as an inactive ingredient

Show Price

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