10 Best Best Hypoallergenic Laundry Detergent of 2025

Tested and Reviewed: Top 10 Best Hypoallergenic Laundry Detergent deals with expert ratings from 8.1 to a perfect 10

March 2026 Edition

Editor's Choice

9.7

Arm & Hammer

ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, 105 fl oz, 105 Loads

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Editor's bottom line:

“This best hypoallergenic laundry detergent is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

One 105 fl oz bottle of ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, Free and Clear Detergent that cleans 105 medium loads when used as directed
Dermatologist-tested, hypoallergenic laundry detergent that's gentle on skin but tough on stains and odors, making it an ideal soap for sensitive skin
Dye-free, worry-free detergent with no perfumes or preservatives is certified 100% by SkinSAFE (1), (1) Certified by SkinSAFE to exclude 100% of their topmost considered skin allergens. In partnership with SkinSAFEproducts.com
With trusted ARM & HAMMER Baking Soda, this HE detergent is formulated to deeply clean clothes while being gentle on skin
HE laundry detergent is concentrated with 2X powerful stain fighters in every load versus leading value detergent, making it an effective and efficient laundry detergent
ARM & HAMMER Baking Soda has been the standard of purity and a trusted household staple in millions of cabinets and pantries for generations of families

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Picked by 397 people today

9.5

Arm & Hammer

ARM & HAMMER Sensitive Skin Free & Clear, 140 Loads Liquid Laundry Detergent, 140 Fl oz

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Main Highlights

One 140 fl oz bottle of ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, Free and Clear Detergent that cleans 140 medium loads when used as directed
Dermatologist-tested, hypoallergenic laundry detergent that's gentle on skin but tough on stains and odors, making it an ideal soap for sensitive skin
Dye-free, worry-free detergent with no perfumes or preservatives is certified 100% by SkinSAFE (1), (1) Certified by SkinSAFE to exclude 100% of their topmost considered skin allergens. In partnership with SkinSAFEproducts.com
With trusted ARM & HAMMER Baking Soda, this HE detergent is formulated to deeply clean clothes while being gentle on skin
HE laundry detergent is concentrated with 2X powerful stain fighters in every load versus leading value detergent, making it an effective and efficient laundry detergent
Clean Deep, Dont Spend Deep
ARM & HAMMER Baking Soda has been the standard of purity and a trusted household staple in millions of cabinets and pantries for generations of families

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9.5

all

all free clear, Original, Liquid Laundry Detergent for Sensitive Skin, Unscented and Hypoallergenic, Concentrated, 82.5oz, 110 Loads

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Main Highlights

all free clear is the #1 laundry detergent brand recommended by dermatologists, allergists and pediatricians for sensitive skin.100% free of perfumes and dyes, all free clear liquid laundry detergent provides an effective clean that's gentle on skin
Now more concentrated. More cleaning power per drop* *vs previous 1.5oz dose formula. Removes impurities without leaving irritating residues** **Like dirt, body oil and allergens
Use with all free clear fabric softener and dryer sheets for clean and soft clothes with static cling reduction in the dryer
all free clear Original is Safer Choice certified which means its been recognized by the United States Environmental Protections Agency (EPA) to be better for you, your family and the planet
all free clear Original includes biodegradable surfactants. Safe for septic systems. Works effectively, even in cold water. As always, contains no phosphates. Safe for all HE washing machines. - Includes one 82.5oz bottle, enough for 110 loads

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9.2

Tide

Tide Free & Gentle Liquid Laundry Detergent, 100 Loads, 132 fl oz, Tide Laundry Detergent, Clean Laundry Detergent

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Main Highlights

DEEP CLEAN FOR SENSITIVE SKIN: Removes more stains than the leading Free detergent while remaining gentle on skin
FREE OF DYES AND PERFUMES: Formulated without dyes and perfumes to help reduce the risk of irritation
CERTIFIED BY EXPERTS: Recognized by the NEA, EPA Safer Choice, and NPF for its sensitive skin formula
WORKS IN ANY MACHINE: Effective in both high efficiency and standard washing machines
CLEANS IN COLD WATER: Designed to deliver cleaning performance even in cold wash cycles
FAMILY FRIENDLY DETERGENT: A suitable choice for fragrance free laundry, free and gentle detergent, and unscented laundry routines
Includes one 132 fl oz, 100 count package of Tide Free & Gentle Liquid Laundry Detergent

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9.0

all

all Laundry Detergent Liquid, Free Clear for Sensitive Skin, Odor Relief, Unscented and Hypoallergenic, 2X Concentrated, 90 Loads

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Main Highlights

all free clear is the #1 laundry detergent brand recommended by dermatologists, allergists and pediatricians for sensitive skin. Unscented and 100% free of perfumes and dyes
Now more concentrated. More cleaning power per drop* *vs previous 1.78oz dose formula. Removes impurities without leaving irritating residues** **Like dirt, body oil and allergens
Use with all free clear fabric softener and dryer sheets for clean and soft clothes with static cling reduction in the dryer
all free clear Odor Relief is Safer Choice certified which means its been recognized by the United States Environmental Protections Agency (EPA) to be better for you, your family and the planet
all free clear Odor Relief includes biodegradable surfactants. Safe for septic systems. Works effectively, even in cold water. As always, contains no phosphates. Safe for all HE washing machines. Includes one 80.1oz bottle, enough for 90 loads

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8.8

all

all Liquid Laundry Detergent, Free Clear for Sensitive Skin with OXI, Unscented and Hypoallergenic, 2X Concentrated, 90 Loads

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Main Highlights

Full of concentrated cleaning power with OXI power for whitening & brightening.
all free clear OXI is Tough on Stains, Gentle on Skin.
100% dye-free and fragrance-free, this hypoallergenic laundry detergent is gentle for sensitive skin.
Safe to use in any washing machine and at any water temperature.
This package includes one 80.1-ounce bottle of all free clear OXI 2X concentrated liquid laundry detergent, enough for 90 loads.

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8.6

ECOS

ECOS Laundry Detergent Liquid, 200 Loads - Dermatologist Tested Laundry Soap - Hypoallergenic, EPA Safer Choice Certified, Plant-Powered - Lavender, 100 Fl Oz (Pack of 2)

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Main Highlights

CLIMATE POSITIVE AND SUSTAINABLE - Not only is this laundry detergent formula effective and kind to sensitive skin, but it's also pH-balanced.
100% VEGAN Containing enough detergent for 200 loads of laundry, plant-powered ECOS Laundry Detergent is both cruelty-free and vegan, making it an ideal choice for planet-conscious households.
PARABEN AND PHOSPHATE FREE - Unlike most conventional laundry detergents, ECOS does not contain any harsh chemicals or ingredients that can pollute water when it enters the ecosystem.
DERMATOLOGIST-TESTED AND HYPOALLERGENIC - ECOS Laundry Detergent is an effective yet gentle cleaning solution for clothes that is suitable for families with skin allergies and sensitivities.
MADE IN USA - Proudly made in the USA with globally sourced ingredients
CLEAN FORMULAS WITH VISIBLE RESULTS - Since 1967, ECOS has created safer, powerful products by using enzymes found in nature. Our liquid laundry detergents are made in a carbon neutral, water neutral, TRUE Platinum Zero Waste factory using 100% renewable energy.
CERTIFIED SAFER CHOICE - Safer Choice certification means that the product perfoms well and contains ingredients that are safer for human health and the environment.
BLACK OWNED AND WOMAN LED - ECOS is a Black-owned and woman-led company

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8.3

Seventh Generation

Seventh Generation Concentrated Laundry Detergent Liquid Free & Clear Fragrance Free 40 oz

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Main Highlights

Seventh Generation Free & Clear Concentrated Laundry Detergent Fragrance-Free has a powerful triple-enzyme formula fights tough stains
Free & Clear hypoallergenic laundry detergent made for sensitive skin
A laundry detergent that is EPA Safer Choice Certified and designed with safety in mind
Concentrated detergent washes 53 medium loads in high-efficiency (HE detergent) or standard machine
USDA Certified 96 percent Biobased laundry detergent liquid made with plant-based ingredients
Caring today for the next seven generations with Seventh Generation liquid detergent; try our dryer sheets and stain remover

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8.1

all

all Liquid Laundry Detergent Free Clear, 118 Ounce, 94 Loads

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Main Highlights

all free clear is the #1 Brand Recommended by Dermatologists, allergists and Pediatricians for Sensitive Skin.
100% free of perfumes and dyes, all free clear effective clean, gentle on skin.
Now more concentrated. More cleaning power per drop* *vs previous 1.50oz dose formula
Use with all free clear fabric softener and dryer sheets for clean and soft clothes with static cling reduction in the dryer.
Removes impurities without leaving irritating residues** **Like dirt, body oil and allergens

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8.1

ECOS

ECOS Laundry Detergent Liquid, 200 Loads - Dermatologist Tested Laundry Soap - Hypoallergenic, EPA Safer Choice Certified, Plant-Powered, Free & Clear, 100 Fl Oz (Pack of 2)

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Main Highlights

CLIMATE POSITIVE AND SUSTAINABLE - Not only is this laundry detergent formula effective and kind to sensitive skin, but it's also pH-balanced.
100% VEGAN Containing enough detergent for 200 loads of laundry, plant-powered ECOS Laundry Detergent is both cruelty-free and vegan, making it an ideal choice for planet-conscious households.
PARABEN AND PHOSPHATE FREE - Unlike most conventional laundry detergents, ECOS does not contain any harsh chemicals or ingredients that can pollute water when it enters the ecosystem.
DERMATOLOGIST-TESTED AND HYPOALLERGENIC - ECOS Laundry Detergent is an effective yet gentle cleaning solution for clothes that is suitable for families with skin allergies and sensitivities.
MADE IN USA - Proudly made in the USA with globally sourced ingredients
CLEAN FORMULAS WITH VISIBLE RESULTS - Since 1967, ECOS has created safer, powerful products by using enzymes found in nature. Our liquid laundry detergents are made in a carbon neutral, water neutral, TRUE Platinum Zero Waste factory using 100% renewable energy.
CERTIFIED SAFER CHOICE - Safer Choice certification means that the product perfoms well and contains ingredients that are safer for human health and the environment.
BLACK OWNED AND WOMAN LED - ECOS is a Black-owned and woman-led company

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Our Best Overall Choice

Best Choice

9.7

Arm & Hammer

ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, 105 fl oz, 105 Loads

Free Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

One 105 fl oz bottle of ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, Free and Clear Detergent that cleans 105 medium loads when used as directed
Dermatologist-tested, hypoallergenic laundry detergent that's gentle on skin but tough on stains and odors, making it an ideal soap for sensitive skin
Dye-free, worry-free detergent with no perfumes or preservatives is certified 100% by SkinSAFE (1), (1) Certified by SkinSAFE to exclude 100% of their topmost considered skin allergens. In partnership with SkinSAFEproducts.com
With trusted ARM & HAMMER Baking Soda, this HE detergent is formulated to deeply clean clothes while being gentle on skin
HE laundry detergent is concentrated with 2X powerful stain fighters in every load versus leading value detergent, making it an effective and efficient laundry detergent
ARM & HAMMER Baking Soda has been the standard of purity and a trusted household staple in millions of cabinets and pantries for generations of families

Show Price

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