10 Best Anti Itch Lotion Extra Strength of 2025

Tested and Reviewed: Top 10 Anti Itch Lotion Extra Strength deals with expert ratings from 8.1 to a perfect 10

June 2025 Edition

Editor's Choice

9.7

Save 16%

CeraVe

CeraVe Moisturizing Cream for Dry Skin Relief, 12 Ounce, Fragrance Free Cream with Pramoxine for Itch Relief

16% OffFree Shipping

Editor's bottom line:

“This anti itch lotion extra strength is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

[ CERAVE ANTI ITCH CREAM ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Rich, velvety texture that is absorbed quickly for softened skin with non-greasy feel.
[ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe itch; clinical study done on 34 subjects. Individual results may vary.
[ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm skin, and Hyaluronic Acid to help retain skins natural moisture.
[ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skins natural barrier
[ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face, body, and hands to temporarily relieve itching. Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free, steroid-free, and non-comedogenic. FSA Eligible & HSA Eligible

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Picked by 294 people today

9.5

CeraVe

CeraVe Anti Itch Moisturizing Lotion with Pramoxine Hydrochloride, Relieves Itch with Minor Skin Irritations, Sunburn Relief, Bug Bites, 8 Ounce

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Main Highlights

[ CERAVE ANTI ITCH LOTION ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Lightweight texture that is absorbed quickly for softened skin with non-greasy feel.
[ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe itch; clinical study done on 34 subjects. Individual results may vary.
[ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm skin, and Hyaluronic Acid to help retain skins natural moisture.
[ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skins natural barrier
[ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face; body; and hands to temporarily relieve itching. Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free; steroid-free; and non-comedogenic. FSA Eligible & HSA Eligible

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9.5

Gold Bond

Gold Bond Medicated Extra Strength Body Lotion, 14 oz., Moisturizes, Relieves & Soothes, Skin Moisturizer

Free Shipping

Main Highlights

Includes one (1) 14-oz. bottle of Gold Bond Medicated Extra Strength Body Lotion
Gold Bond Extra Strength Lotion's triple action formula moisturizes, soothes, and cools dry, itchy skin
This anti-itch lotion is formulated with aloe and vitamin E to soothe irritated skin
Gold Bond Medicated Lotion delivers lasting hydration while it protects skin with seven moisturizers
Use body lotion to relieve pain and itch associated with sunburn, insect bites, and minor cuts, burns, and scrapes
Create a TerraCycle account and start recycling your empty Gold Bond packaging

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9.2

Eucerin

Eucerin Itch Relief Intensive Calming Body Lotion for Dry Itchy Skin, Unscented Lotion with Cooling Menthol and Ceramides, 8.4 Fl Oz Bottle

Free Shipping

Main Highlights

12-Hour Relief: This Eucerin sensitive skin lotion immediately relieves and calms itchiness caused by dry skin for up to 12 hours
Formulated with Menthol: Eucerin lotion for itchy skin formulated with menthol to provide instant relief from the itch caused by dry skin
Soft and Smooth Skin: This body moisturizer is enriched with Ceramides to help strengthen the skin and leave it feeling soft and smooth
Free Of: This non-greasy unscented lotion is dye free, paraben free and absorbs quickly into skin
Includes one (1) 8.4 fluid ounce bottle of Eucerin Itch Relief Intensive Calming Body Lotion, Fragrance Free Lotion for Dry Itchy Skin

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9.0

Save 6%

Curel

Curel Itch Defense Calming Body Lotion, Moisturizer for Dry, Itchy Skin, Body and Hand Lotion, with Advanced Ceramide Complex, Pro-Vitamin B5, Shea Butter, 20 Oz

6% OffFree Shipping

Main Highlights

RELIEF FROM ITCHY SKIN - Curél Itch Defense is clinically proven to relieve dry, itchy skin, and help to control flare-ups.
SKIN MOISTURIZER - Restores the skin's' moisture barrier to prevent irritation from returning
SAFE FOR MOST SKIN TYPES - Suitable for use on babies 6 months and up
ECZEMA RELIEF TREATMENT - Soothes eczema-prone skin; Granted the National Eczema Association Seal of Acceptance
SKIN REPAIR - With Advanced Ceramide Complex, the lotion rebalances ceramide levels, pH levels, moisture levels and cellular turnover

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8.8

Save 9%

Sarna

Sarna Sensitive Steroid-Free Anti-Itch Lotion for Dry Irritated Skin, Fragrance free - 7.5 Fl Oz

9% OffFree Shipping

Main Highlights

Intensive relief - Soothes itching from eczema and dry skin conditions
Targeted relief - Can be applied directly to the site of the itching for targeted relief
Designed for sensitive skin - Contains no steroids, no parabens and no fragrances
Daily moisturizer - Helps restore moisture to skin and is gentle enough for daily use

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8.6

Gold Bond

Gold Bond Medicated Extra Strength Body Lotion, 14 oz., Moisturizes, Relieves & Soothes

Free Shipping

Main Highlights

Includes one (1) 14-oz. bottle of Gold Bond Medicated Extra Strength Body Lotion
Gold Bond Extra Strength Lotion's triple action formula moisturizes, soothes, and cools dry, itchy skin
This anti-itch lotion is formulated with aloe and vitamin E to soothe irritated skin
Gold Bond Medicated Lotion delivers lasting hydration while it protects skin with five moisturizers
Use body lotion to relieve pain and itch associated with sunburn, insect bites, and minor cuts, burns, and scrapes
Create a TerraCycle account and start recycling your empty Gold Bond packaging

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8.3

Aveeno

Anti-Itch Concentrated Lotion with Triple Oat Complex 4 fl Ounce (118 ml) Lotion

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Main Highlights

FAST-ACTING RELIEF: In just one application, it soothes intense itching, discomfort, and irritation
LONG-LASTING MOISTURE: This dermatologist-recommended formula provides deep hydration that lasts for hours, helping to prevent dry, itchy skin flare-ups
SOOTHING POWER: Harnesses the calming properties of colloidal oatmeal to soothe irritated skin and reduce inflammation gently
GENTLE LOTION: Gentle enough for sensitive skin, this fragrance-free lotion hydrates daily for adults and children over 2
CONVENIENT SIZE: The bottle is perfect for at-home use or to take with you on the go for itch relief whenever you need it

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8.1

Gold Bond

Gold Bond Medicated Maximum Strength Pain & Itch Relief Cream, 1.75 oz., with Lidocaine

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Main Highlights

Includes one (1) 1.75-oz. tube of Gold Bond Medicated Maximum Strength Pain & Itch Relief Cream With Lidocaine
Gold Bond Pain & Itch Cream with Lidocaine numbs away itching and pain due to minor skin irritations
This pain and itch formula contains 4% lidocaine, the maximum strength available without a prescription*
Gold Bond Lidocaine Cream starts working fast to relieve itching and pain associated with minor skin irritations
This numbing cream is great for relieving pain and itch associated with sunburn, insect bites, and minor cuts, burns, and scrapes
Create a TerraCycle account and start recycling your empty Gold Bond packaging

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Best Value

8.1

Save 26%

Benadryl

Benadryl Anti Itch Gel, Relief of Outdoor Itches Associated with Poison Ivy, Topical Analgesic, Cooling Relief, Diphenhydramine, 3.5 oz

26% OffFree Shipping

Main Highlights

ANTI ITCH GEL: Benadryl anti itch gel temporarily provides pain and itch relief associated with insect bites, minor burns, sunburn, minor skin irritation, minor cuts and scrapes, and rashes due to poison ivy and poison sumac.
TOPICAL ANALGESIC: Topical cooling gel contains 2% of the topical analgesic pain reliver diphenhydramine hydrochloride that helps to relieve itches and minor pains on the skin; Provides relief from most outside itches.
SOOTHING & COOLING GEL: Carry this topical anti itch analgesic gel to relieve uncomfortable skin irritation at home or on the go; Works when you need it most and provides cooling relief from minor pain to intolerable itchy skin.
POISON IVY REIEF: Topical Analgesic to provide itch relief for most outdoor itches associated with poison ivy, insect bites; Dries the oozing and weeping of poison ivy, poison oak and poison sumac.
INCLUDES: Pack of 1, 3.5 fl. oz. anti itch gel; Suitable for adults and children ages 2+; Provides itch relief for kids and adults alike and great to keep on hand during outdoor activities such as camping, hiking, or walking with the family.

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Our Best Overall Choice

Best Choice

9.7

CeraVe

CeraVe Moisturizing Cream for Dry Skin Relief, 12 Ounce, Fragrance Free Cream with Pramoxine for Itch Relief

16% OffFree Shipping

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

[ CERAVE ANTI ITCH CREAM ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Rich, velvety texture that is absorbed quickly for softened skin with non-greasy feel.
[ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe itch; clinical study done on 34 subjects. Individual results may vary.
[ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm skin, and Hyaluronic Acid to help retain skins natural moisture.
[ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skins natural barrier
[ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face, body, and hands to temporarily relieve itching. Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free, steroid-free, and non-comedogenic. FSA Eligible & HSA Eligible

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Eucerin Skin Calming Lotion - Full Body Lotion for Dry, Itchy Skin, Natural Oatmeal Enriched - 16.9 fl. oz Pump Bottle

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Anti-Itch Concentrated Lotion with Triple Oat Complex 4 fl Ounce (118 ml) Lotion

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Lubriderm Advanced Therapy Fragrance Free Moisturizing Hand & Body Lotion + Pro-Ceramide with Vitamins E & Pro-Vitamin B5, Intense Hydration for Itchy, Extra Dry Skin, Non-Greasy, 16 fl. oz

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Aveeno, Anti-Itch Concentrated Lotion, 4 fl oz

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Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.

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Lotion for Dry Skin by Caladryl, Topical Analgesic for Itch Relief, 6 Fl Oz

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Amazon Basic Care Maximum Strength 1% Hydrocortisone Anti-Itch Lotion for Eczema, 3.5 ounce (Pack of 1)

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A+Health Extra Strength Itch Relief Gel, Diphenhydramine HCl 2% Topical Analgesic, Relives Itching and Pain for Bug Bites, Rashes, Poison Ivy, Oak and Sumac, Made in USA, 4 Ounces

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Benadryl Extra Strength Anti-Itch Topical Cream with 2% Diphenhydramine HCI for Itch Relief of Outdoor Itches Associated with Poison Ivy, Insect Bites & More, 1 fl oz

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