10 Best Ant And Roach Killer Powder of 2025

Tested and Reviewed: Top 10 Ant And Roach Killer Powder deals with expert ratings from 8.1 to a perfect 10

April 2026 Edition

Editor's Choice

9.7

Save 28%

HARRIS

HARRIS Boric Acid Roach and Silverfish Killer Powder w/Lure for Insects (16oz)

28% Off

Editor's bottom line:

“This ant and roach killer powder is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Long Lasting - Continues to kill roaches, palmetto bugs, water bugs and silverfish for weeks after application as long as it's kept dry
Fast Acting - Insects coming into contact with the powder will die within 72 hours after initial contact
Easy Application - The puffer bottle makes application quick and simple for difficult to reach areas
Contains Irresistible Lure - Harris food grade lure attracts roaches from their hiding places
EPA Registered - Made in the USA & Registered with the Environmental Protection Agency (No. 3-10) for use in homes with people and pets

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Picked by 397 people today

9.5

Ortho

Ortho Orthene Ant and Roach Killer, Provides Long-Lasting Insect Control, for Indoor and Outdoor Use, 1 lb.

Main Highlights

Ortho Orthene Ant & Roach Killer is a ready-to-use insect killer dust that works to kill listed insects for up to 8 months
This odorless insect killer controls ants, roaches, fleas, ticks, spiders, scorpions, stink bugs and other listed pests
Use this pest control product indoors to treat cracks, crevices and other hiding and runway areas; apply outdoors as a perimeter treatment or to ornamentals, flowers and listed vegetable plants
Our roach and ant killer is for residential use in and around homes, ornamentals, shrubs, and vegetable gardens
Application rates for Ortho Orthene Ant & Roach Killer vary; please review all label directions before use

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9.5

Save 22%

Terro

TERRO Ant Dust Powder Killer for Indoors and Outdoors - Kills Ants, Fire Ants, Roaches, Spiders, and Other Insects - T600 - Up to 8 Months Protection - Easy to Use

22% Off

Main Highlights

KILL ANTS & OTHER INSECTS: TERRO Ant Dust kills ants (including fire & carpenter ants), cockroaches, spiders and other insects
WATERPROOF FORMULA: The waterproof dust won't wash in the rain, ensuring lasting protection from insects in your yard
KILLS ON CONTACT: This ready-to-use ant dust kills insects on contact
UP TO 8 MONTHS OF PROTECTION: Provides long-lasting residual control, continuing to kill ants and other insects for up to 8 months
EASY TO APPLY: The convenient shaker canister allows for both scatter and widespread application
INDOOR & OUTDOOR USE: Apply in cracks and crevices, around perimeters and foundations, in crawls spaces and wall voids, in flower beds, and directly on ant hills
Waterproof
Lasts up to 8 Months
Kills Carpenter Ants
Deltamethrin

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9.2

JT Eaton

Crawling Insect Killer, Powder

Main Highlights

PROVEN PEST CONTROL: Eliminates roaches, ants, and other labeled insects with a simple and effective boric acid formula
LOW HAZARD FORMULA: Contains low-risk boric acid powder, making it a safer option for use around the home
USER-FRIENDLY APPLICATION: Comes in an easy-to-use puffer bottle for precise and mess-free application
VERSATILE PROTECTION: Ideal for targeting indoor infestations, ensuring your space remains pest-free
LEGACY OF TRUST: Since 1932, JT Eaton has been a trusted partner for PMPs worldwide, pioneering solutions like the first paraffin bait block and modern glue board. Today, we continue to lead with innovative products for both the pest control and retail industries.

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9.0

Ortho

Ortho Orthene Fire Ant Killer1, Kills The Queen, Destroys up to 189 Mounds, Begins Working in 60 Minutes, 14 oz.

Main Highlights

Ortho Orthene Fire Ant Killer1 kills the queen, destroys the mound, and treats up to 189 mounds
This fire ant killer begins killing in just 60 minutes so you can get back to enjoying your yard fast
Kill fire ants outdoors on your lawn and around ornamental plants, including flowers, trees and shrubs
To treat fire ant mounds, simply sprinkle the product over each mound using amount specified on the product label
Use as part of the Ortho 2-Step System with Ortho Fire Ant Killer Broadcast Granules (sold separately), which prevents new fire ant mounds from forming for up to 6 months

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8.8

HARRIS

Harris 8 oz Diatomaceous Earth Crawling Insect Killer — 100% Natural Dust for Ants, Roaches, Bed Bugs, Fleas — Indoor & Outdoor Use

Main Highlights

POWERFUL CRAWLING INSECT KILLER : Effectively kills a wide range of crawling insects including ants, bed bugs, cockroaches, fleas, earwigs, silverfish, and spiders. A natural solution for indoor and outdoor pest control without harsh chemicals.
100% DIATOMACEOUS EARTH WITH NO ADDITIVES : Made from pure freshwater diatomaceous earth, this powder is non-toxic, pet-friendly (when used as directed), and safe for use around kids and animals. A trusted choice for eco-conscious households.
KILLS INSECTS MECHANICALLY, NOT CHEMICALLY : Works by dehydrating insects on contact through physical abrasion. Insects walk through the powder and the fine particles damage their exoskeleton, leading to rapid dehydration and death.
LONG-LASTING INDOOR & OUTDOOR PROTECTION : Remains effective as long as the powder stays dry. Use in basements, attics, gardens, garages, and entry points to create a barrier against future infestations.
EPA REGISTERED - Registered with the Environmental Protection Agency (No. 3-18)
BUILT-IN PUFFER TIP FOR PRECISE CONTROL The included powder duster features a narrow, easy-to-use puffer tip that allows for targeted application in tight spaces and cracks. Apply just the right amount of diatomaceous earth exactly where insects hideno waste, no mess.
TRUSTED BRAND SINCE 1928: Harris has been providing effective pest control and insect management solutions for nearly a century, trusted by professionals and homeowners alike.

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8.6

Save 19%

Ortho

Ortho Orthene Fire Ant Killer1, Kills the Queen and Destroys Mounds, Begins Working in 60 minutes, 12 oz., 2-Pack

19% Off

Main Highlights

Ortho Orthene Fire Ant Killer1 kills the queen, destroys the mound and treats up to 162 mounds
This fire ant killer begins killing in just 60 minutes so you can get back to enjoying your yard fast
Kill fire ants outdoors on your lawn and around ornamental plants, including flowers, trees and shrubs
To treat fire ant mounds, simply sprinkle the product over each mound using amount specified on the product label, no watering-in needed
This pack includes two 12 oz. bottles of Ortho Orthene Fire Ant Killer1; for best results, use as part of the Ortho 2-Step System with Ortho Fire Ant Killer Broadcast Granules (sold separately)

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Best Value

8.3

Save 30%

Terro

TERRO Ant Killer Plus Multi-Purpose Insect Control for Outdoors - Kills Fire Ants, Fleas, Cockroaches, and Other Crawling Insects - 3lb Shaker Bag - T901-6

30% Off

Main Highlights

SAY GOODBYE TO BUGS: TERRO Ant Killer Plus kills ants, fire ants, roaches, fleas, crickets, earwigs, millipedes, mites, palmetto bugs, silverfish, sow bugs, and more
QUICK RESULTS: The powerful insect killing granules kill listed insect pests within 24 hours of contact while also providing residual repellency
OUTDOOR USE ONLY: These insect killing granules are for outdoor use only. Apply the granules as band treatment around house foundations and on lawns, or as a spot treatment on ant hills
EASY TO APPLY: The resealable shaker bag design allows for convenient application. There's no chemical spreader or broadcaster required
GREAT VALUE: The shaker bag holds 3 pounds of insecticide granules

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8.1

Enoz

Enoz Roach Away Boric Acid Powder - (2 Pack) 16 oz Bag - Kills Cockroaches, Silverfish, and Ants - Boric Acid Roach Killer and Ant Killer Powder

Main Highlights

ROACH KILLER POWDER: Roach killer made with boric acid that is odorless and non-staining; Easily sprinkle around the house to kill roaches and prevent a future roach infestation; Designed for indoor use; Includes two 1-pound bags
MADE WITH BORIC ACID: Cockroach and ant control made with 99% Boric Acid; Boric acid pest control kills roaches that ingest it; The powder clings to the bodies of roaches that walk through treated areas and is ingested when the roaches groom themselves
PROTECT YOUR HOME: Boric acid powder is easy-to-use and can be used throughout your home; Sprinkle behind the refrigerator and stove, under the sink, around drain openings, along baseboards, in corners of cabinets, and inside closets
KILLS COMMON HOUSEHOLD PESTS: Kills cockroaches (palmetto bugs, waterbugs), silverfish, and ants
SAFETY FIRST: Any powder visible after application must be brushed into cracks or removed; Apply only in areas inaccessible to children and pets; Do not treat pets with this product; Avoid contamination of food and ornamental plants

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8.1

Save 17%

Lilly's Naturals

Diatomaceous Earth Food Grade with Peppermint Oil Crawling Insect Killer | Indoor Pest Control Powder for Bed Bug, Roach, Ant, Fleas | Lilly's naturals, 12 fl oz

17% Off

Main Highlights

Bed Bug Killer - Our food grade diatomaceous earth with peppermint & clove oil works to kill and deter crawling insects & pests from your home.
Flea Powder for Carpets - Natural & Effective Formula Made with food-grade diatomaceous earth enhanced with peppermint and clove oils for added repellency and freshness. The perfect insect killer powder.
Family & Pet Friendly Safe to use around children and pets when applied as directedno harsh residues, just peace of mind.
Indoor & Outdoor Insect Repellent Dust Works in bedrooms, kitchens, and living areas, as well as basements, garages, patios, and entryways.
Easy-to-Apply Spout Bottle Convenient packaging makes it simple to spread DE powder directly onto problem areas for lasting protection.

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Our Best Overall Choice

Best Choice

9.7

HARRIS

HARRIS Boric Acid Roach and Silverfish Killer Powder w/Lure for Insects (16oz)

28% Off

Editor's bottom line:

“This is the best one we tested. In terms of quality, brand and price, we couldn't ask for more.”

Main Highlights

Long Lasting - Continues to kill roaches, palmetto bugs, water bugs and silverfish for weeks after application as long as it's kept dry
Fast Acting - Insects coming into contact with the powder will die within 72 hours after initial contact
Easy Application - The puffer bottle makes application quick and simple for difficult to reach areas
Contains Irresistible Lure - Harris food grade lure attracts roaches from their hiding places
EPA Registered - Made in the USA & Registered with the Environmental Protection Agency (No. 3-10) for use in homes with people and pets

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Deals are Live

Special Amazon deal ends in:

10 Best Ant And Roach Killer Powder of 2025

Tested and Reviewed: Top 10 Ant And Roach Killer Powder deals with expert ratings from 8.1 to a perfect 10

HARRIS

HARRIS Boric Acid Roach and Silverfish Killer Powder w/Lure for Insects (16oz)

Editor's bottom line:

Main Highlights

Ortho

Ortho Orthene Ant and Roach Killer, Provides Long-Lasting Insect Control, for Indoor and Outdoor Use, 1 lb.

Main Highlights

Terro

TERRO Ant Dust Powder Killer for Indoors and Outdoors - Kills Ants, Fire Ants, Roaches, Spiders, and Other Insects - T600 - Up to 8 Months Protection - Easy to Use

Main Highlights

JT Eaton

Crawling Insect Killer, Powder

Main Highlights

Ortho

Ortho Orthene Fire Ant Killer1, Kills The Queen, Destroys up to 189 Mounds, Begins Working in 60 Minutes, 14 oz.

Main Highlights

HARRIS

Harris 8 oz Diatomaceous Earth Crawling Insect Killer — 100% Natural Dust for Ants, Roaches, Bed Bugs, Fleas — Indoor & Outdoor Use

Main Highlights

Ortho

Ortho Orthene Fire Ant Killer1, Kills the Queen and Destroys Mounds, Begins Working in 60 minutes, 12 oz., 2-Pack

Main Highlights

Terro

TERRO Ant Killer Plus Multi-Purpose Insect Control for Outdoors - Kills Fire Ants, Fleas, Cockroaches, and Other Crawling Insects - 3lb Shaker Bag - T901-6

Main Highlights

Enoz

Enoz Roach Away Boric Acid Powder - (2 Pack) 16 oz Bag - Kills Cockroaches, Silverfish, and Ants - Boric Acid Roach Killer and Ant Killer Powder

Main Highlights

Lilly's Naturals

Diatomaceous Earth Food Grade with Peppermint Oil Crawling Insect Killer | Indoor Pest Control Powder for Bed Bug, Roach, Ant, Fleas | Lilly's naturals, 12 fl oz

Main Highlights

Our Best Overall Choice

HARRIS

HARRIS Boric Acid Roach and Silverfish Killer Powder w/Lure for Insects (16oz)

Editor's bottom line:

Main Highlights

Deals are Live

Harris 8 oz Diatomaceous Earth Crawling Insect Killer — 100% Natural Dust for Ants, Roaches, Bed Bugs, Fleas — Indoor & Outdoor Use